Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes. [PDF]
Front Immunol, 2018 Keizer MP +4 more
europepmc +2 more sources
Recognition of <i>Staphylococcus aureus</i> by the pattern recognition molecules langerin, mannan-binding lectin, and surfactant protein D: the influence of capsular polysaccharides and wall teichoic acid. [PDF]
Front ImmunolHymøller KM +5 more
europepmc +3 more sources
Cooperative Stimulation of Dendritic Cells by Cryptococcus neoformans Mannoproteins and CpG Oligodeoxynucleotides [PDF]
, 2008 While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC response to mannosylated antigens ...
Dan, Jennifer M. +3 more
core +14 more sources
3D Structural View of Pathogen Recognition by Mammalian Lectin Receptors
Frontiers in Molecular Biosciences, 2021 Humans and other mammals resist exogenous pathogens by recognizing them as non-self. How do they do this? The answer lies in the recognition by mammalian lectin receptors of glycans usually found on the surface of pathogens and whose chemical structure ...
Noriyoshi Manabe, Yoshiki Yamaguchi
doaj +1 more source
A novel bifunctional hybrid with marine bacterium alkaline phosphatase and Far Eastern holothurian mannan-binding lectin activities. [PDF]
PLoS ONE, 2014 A fusion between the genes encoding the marine bacterium Cobetia marina alkaline phosphatase (CmAP) and Far Eastern holothurian Apostichopus japonicus mannan-binding C-type lectin (MBL-AJ) was performed. Expression of the fusion gene in E.
Larissa Balabanova +6 more
doaj +1 more source
Thyroid hormone increases mannan-binding lectin levels [PDF]
European Journal of Endocrinology, 2005 Background: Recent studies have indicated the existence of causal links between the endocrine and immune systems and cardiovascular disease. Mannan-binding lectin (MBL), a protein of the innate immune system, may constitute a connection between these fields.
Riis, Anne Lene Dalkjaer +8 more
openaire +3 more sources
PLoS Neglected Tropical Diseases, 2020 BackgroundDeposition of complement factors on Mycobacterium leprae may enhance phagocytosis. Such deposition may occur through the lectin pathway of complement.
Hellen Weinschutz Mendes +5 more
doaj +1 more source
Dengue and the Lectin Pathway of the Complement System
Viruses, 2021 Dengue is a mosquito-borne viral disease causing significant health and economic burdens globally. The dengue virus (DENV) comprises four serotypes (DENV1-4).
Romchat Kraivong +4 more
doaj +1 more source
Letter to the Editor: LO2, a misidentified cell line: Some data should be interpreted with caution
, 2022 Hepatology, EarlyView.
Ralf Weiskirchen
wiley +1 more source
Frontiers in Immunology, 2023 IntroductionOveractivation of the lectin pathway of complement plays a pathogenic role in a broad range of immune-mediated and inflammatory disorders; mannan-binding lectin-associated serine protease-2 (MASP-2) is the key effector enzyme of the lectin ...
Thomas Dudler +2 more
doaj +1 more source