Results 41 to 50 of about 14,274 (254)

Association of Chlamydia pneumoniae with coronary artery disease and its progression is dependent on the modifying effect of mannose-binding lectin [PDF]

, 2002
Background— The possible association between coronary artery disease (CAD) and Chlamydia pneumoniae (C pneumoniae) infection is controversial. On the basis of the recent suggestion that mannose-binding lectin (MBL) variant alleles are related to an ...
Burián, Katalin, Duba, Jenő, Endrész, Valéria, Füst, György, Garred, Peter, Gönczöl, Éva, Karádi, István, Madsen, Hans O., Prohászka, Zoltán, Romics, László, Rugonfalvi-Kiss, Szabolcs   +10 more
core   +1 more source

Phosphomannosyl receptors may participate in the adhesive interaction between lymphocytes and high endothelial venules. [PDF]

, 1984
Normal and malignant lymphocytes can migrate from the bloodstream into lymph nodes and Peyer's patches. This process helps distribute normal lymphocytes throughout the lymphoid system and may provide a portal of entry for circulating malignant cells.
Rosen, SD, Stoolman, LM, Tenforde, TS
core   +1 more source

Signalling C-Type Lectins in Antimicrobial Immunity [PDF]

, 2013
Funding: This work was funded by the Wellcome Trust, Medical Research Council and the University of Aberdeen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Brown, Gordon D., Drummond, Rebecca A.
core   +7 more sources

The Macrophage Mannose Receptor Regulate Mannan-Induced Psoriasis, Psoriatic Arthritis, and Rheumatoid Arthritis-Like Disease Models

Frontiers in Immunology, 2018
The injection of mannan into mice can result in the development of psoriasis (Ps) and psoriatic arthritis (PsA), whereas co-injection with antibodies toward collagen type II leads to a chronic rheumatoid-like arthritis.
Cecilia Hagert, Cecilia Hagert, Outi Sareila, Outi Sareila, Tiina Kelkka, Tiina Kelkka, Sirpa Jalkanen, Rikard Holmdahl, Rikard Holmdahl   +8 more
doaj   +1 more source

Mannan detecting C-type lectin receptor probes recognise immune epitopes with diverse chemical, spatial and phylogenetic heterogeneity in fungal cell walls.

PLoS Pathogens, 2020
During the course of fungal infection, pathogen recognition by the innate immune system is critical to initiate efficient protective immune responses. The primary event that triggers immune responses is the binding of Pattern Recognition Receptors (PRRs),
Ingrida Vendele, Janet A Willment, Lisete M Silva, Angelina S Palma, Wengang Chai, Yan Liu, Ten Feizi, Maria Spyrou, Mark H T Stappers, Gordon D Brown, Neil A R Gow   +10 more
doaj   +1 more source

A truncated lipoglycan from mycobacteria with altered immunological properties [PDF]

, 2010
Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol targets arabinogalactan and lipoarabinomannan (LAM) biosynthesis through the inhibition of several ...
Alderwick, Luke J., Appelmelk, B. J., Besra, Gurdyal S, Bhatt, Apoorva, Birch, Helen, Eggeling, Lothar, Geurtsen, J, Maaskant, J, Nigou, Jerome, Singh, Albel   +9 more
core   +2 more sources

Mannan‐Binding Lectin Inhibits Humoural Responses [PDF]

Scandinavian Journal of Immunology, 2004
Chronic hepatitis B virus (HBV) infection affects about 200–400 million people worldwide and represents one of the leading causes for liver cirrhosis and hepatocellular carcinoma. Control over the HBV infection is achieved mainly by vaccination with Hepatitis B surface antigen (HBsAg).
M. Ruseva, M. Gajdeva, K. Takahashi, A. Ezekowitz, S. Thiel, J. C. Jensenius   +5 more
openaire   +1 more source

A detailed study on understanding glycopolymer library and Con A interactions [PDF]

, 2013
Synthetic glycopolymers are important natural oligosaccharides mimics for many biological applications. To develop glycopolymeric drugs and therapeutic agents, factors that control the receptor-ligand interaction need to be investigated.
Becer, C. Remzi, Burns, James A., Geng, Jin, Gou, Yanzi, Haddleton, David M., Richards, Sarah-Jane   +5 more
core   +1 more source

The neck region of the C-type lectin DC-SIGN regulates its surface spatiotemporal organization and virus-binding capacity on antigen presenting cells [PDF]

, 2012
The C-type lectin DC-SIGN expressed on dendritic cells (DCs) facilitates capture and internalization of a plethora of different pathogens. Although it is known that DC-SIGN organizes in nanoclusters at the surface of DCs, the molecular mechanisms ...
Alvarez, Ashby, Bakker, Banchereau, Bonifaz, Cambi, Cambi, Cambi, Cambi, Cambi, Chung, de Bakker, de Witte, Feinberg, Feinberg, Gaborski, Geijtenbeek, Geijtenbeek, Geijtenbeek, Geijtenbeek, Gringhuis, Itano, Itano, Khoo, Koopman, Liu, Liu, Lozach, Lozach, Ludwig, Menon, Mitchell, Neumann, Pohlmann, Puig-Kröger, Rappocciolo, Regan, Serrano-Gómez, Sierra-Filardi, Simmons, Smith, Soilleux, Steinman, Tacken, Tacken, Théry, Trombetta, van Kooyk, Yu, Zhu   +49 more
core   +5 more sources

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, EarlyView.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +2 more sources