Results 51 to 60 of about 6,257 (206)

Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli

ChemBioChem, EarlyView.
This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa, Shane M. Coyle, Fiona Walsh, Trinidad Velasco‐Torrijos   +3 more
wiley   +1 more source

Sterile Inflammation of Brain, due to Activation of Innate Immunity, as a Culprit in Psychiatric Disorders

Frontiers in Psychiatry, 2018
Evidence has accumulated that the occurrence of psychiatric disorders is related to chronic inflammation. In support of this linkage, changes in the levels of circulating pro-inflammatory cytokines and chemokines in the peripheral blood (PB) of ...
Mariusz Z. Ratajczak, Mariusz Z. Ratajczak, Daniel Pedziwiatr, Monika Cymer, Magda Kucia, Magda Kucia, Jolanta Kucharska-Mazur, Jerzy Samochowiec   +7 more
doaj   +1 more source

Dissection of the anti-Candida albicans mannan immune response using synthetic oligomannosides reveals unique properties of β-1,2 mannotriose protective epitopes

Scientific Reports, 2021
Candida albicans mannan consists of a large repertoire of oligomannosides with different types of mannose linkages and chain lengths, which act as individual epitopes with more or less overlapping antibody specificities. Although anti-C.
Boualem Sendid, Karine Lecointe, Mayeul Collot, Pierre-Marie Danzé, Sébastien Damiens, Anne-Sophie Drucbert, Chantal Fradin, Jean-Pierre Vilcot, Frédéric Grenouillet, Faustine Dubar, Jérôme de Ruyck, Samir Jawhara, Jean-Maurice Mallet, Daniel Poulain   +13 more
doaj   +1 more source

Interaction of C1q and Mannan-Binding Lectin with Viruses

Immunobiology, 2002
As soluble recognition molecules of innate immunity, C1q and MBL are able to bind directly to various viruses, including retroviruses and influenza viruses. Interaction of C1q with retroviruses and certain infected cells was shown to involve the globular region of C1q and viral envelope glycoproteins, such as p15E of MuLV, gp41 and gp120 of HIV-1, gp21
Pascale Tacnet-Delorme, Gérard J. Arlaud, Nicole M. Thielens   +2 more
openaire   +3 more sources

Differential activity of a lectin from Solieria filiformis against human pathogenic bacteria

Brazilian Journal of Medical and Biological Research, 2005
A lectin isolated from the red alga Solieria filiformis was evaluated for its effect on the growth of 8 gram-negative and 3 gram-positive bacteria cultivated in liquid medium (three independent experiments/bacterium).
M.L. Holanda, V.M.M. Melo, L.M.C.M. Silva, R.C.N. Amorim, M.G. Pereira, N.M.B. Benevides   +5 more
doaj   +1 more source

Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model

Frontiers in Immunology, 2022
BackgroundComplement lectin pathway components, in particular mannan-binding lectin (MBL) and MBL-associated serine proteases (MASPs) have been shown to interact with coagulation factors and contribute to clot formation.
Murielle Golomingi, Jessie Kohler, Lorenz Jenny, Elaissa T. Hardy, József Dobó, Péter Gál, Gábor Pál, Bence Kiss, Wilbur A. Lam, Verena Schroeder   +9 more
doaj   +1 more source

The Life of a Kidney Podocyte

Acta Physiologica, Volume 241, Issue 8, August 2025.
ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth, Wiebke Sachs, Catherine Meyer‐Schwesinger   +2 more
wiley   +1 more source

A Modular Solid Phase Synthesis Approach for Glycocalix[4]Arene Derivatives and Their Multivalent Presentation on Ultrasmall Gold Nanoparticles.

Chemistry – A European Journal, Volume 31, Issue 40, July 17, 2025.
In this study, we present a calix[4]arene building block suitable for modular solid‐phase polymer synthesis and the preparation of functional glycocalix[4]arene. This allows us to incorporate carbohydrate ligands and further functionalities, such as alkynes at a specific position at the upper or lower rim of the calix[4]arene as demonstrated for the ...
Alisa Kayser, Kai Klein, Daria Babushkina, Anne Sakse, Gisele Mouafo Kenne, Ulla I.M. Gerling‐Driessen, Monir Tabatabai, Matthias Epple, Laura Hartmann   +8 more
wiley   +1 more source

Activation of complement system by mannan pathway and Mbl2 genotypes in patients with type 2 diabetes and nephropathy

Zdravniški Vestnik, 2014
To add new evidence that complement activation by the mannan (lectin) pathway is involved in the pathogenesis of nephropathy in patients with type 2 diabetes, we collected blood and urine samples from 20 patients with type 2 diabetes and nephropathy and ...
Tjaša Cerar, Draženka Pongrac Barlovič, Anže Zorin, Nadan Gregorič, Vladimir Kotnik   +4 more
doaj  

Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide

BMC Immunology, 2011
Background Mannan-binding lectin (MBL) is a pattern-recognition molecule present in serum, which is involved in the innate immune defense by activating complement and promoting opsonophagocytosis. Dendritic cells (DCs) are professional antigen presenting
Zhang Liyun, Chen Yue, Zhang Yani, Wang Mingyong, Lu Xiao, Chen Zhengliang   +5 more
doaj   +1 more source