Results 51 to 60 of about 13,265 (210)

Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection [PDF]

, 2005
Little is known about the innate immune response to severe acute respiratory syndrome (SARS) coronavirus (CoV) infection. Mannose-binding lectin (MBL), a key molecule in innate immunity, functions as an ante-antibody before the specific antibody response.
Chan, EYT, Chow, EY, Ip, WKE, Jensenius, JC, Ka, LA, Kong, EKP, Kwok, HC, Law, HKW, Lim, W, Peiris, JSM, Tso, GHW, Turner, MW, Wong, WHS, Yu, LL, Yuk, FT, Yung, RWH   +15 more
core   +1 more source

Targeting antigens to dendritic cell receptors for vaccine development [PDF]

, 2013
Dendritic cells (DCs) are highly specialized antigen presenting cells of the immune system which play a key role in regulating immune responses. Depending on the method of antigen delivery, DCs stimulate immune responses or induce tolerance.
Apostolopoulos, Vasso, Stojanovska, Lily, Thalhammer, T, Tzakos, AG   +3 more
core   +2 more sources

Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection [PDF]

, 2010
BACKGROUND: Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, inhibits influenza A virus infection in vitro. MBL deficiency due to gene polymorphism in humans has been associated with infection susceptibility.
Kazue Takahashi, Kevan L Hartshorn, Mitchell R White, Patience Moyo, Sheree McClear, Steffen Thiel, Wei-Chuan Chang   +6 more
core   +5 more sources

Clinical manifestations of mannan-binding lectin deficiency

Molecular Immunology, 2006
Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy of the immune system.
Thiel, Steffen, Frederiksen, Pernille Dorthea, Jensenius, Jens Christian   +2 more
openaire   +3 more sources

Mannan-Binding Lectin Enhances Susceptibility to Visceral Leishmaniasis [PDF]

Infection and Immunity, 2001
ABSTRACTLevels of the serum opsonin mannan-binding lectin (MBL) were directly correlated with the probability of developing visceral leishmaniasis. Monocytes infected with MBL-opsonizedLeishmania chagasipromastigotes secreted higher levels of tumor necrosis factor alpha and interleukin-6 than cells infected with nonopsonized parasites.
I K, Santos, C H, Costa, H, Krieger, M F, Feitosa, D, Zurakowski, B, Fardin, R B, Gomes, D L, Weiner, D A, Harn, R A, Ezekowitz, J E, Epstein   +10 more
openaire   +2 more sources

Carbohydrate specificity of sea urchin sperm bindin: a cell surface lectin mediating sperm-egg adhesion. [PDF]

, 1982
We have examined the carbohydrate specificity of bindin, a sperm protein responsible for the adhesion of sea urchin sperm to eggs, by investigating the interaction of a number of polysaccharides and glycoconjugates with isolated bindin.
Glabe, CG, Grabel, LB, Rosen, SD, Vacquier, VD   +3 more
core  

Infusion of plasma-derived mannan-binding lectin (MBL) into MBL-deficient humans. [PDF]

, 2003
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldOur first experience of mannan-binding lectin (MBL)-replacement therapy was with a patient experiencing recurrent erythema multiforme associated
Valdimarsson, H
core   +1 more source

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID

Immunology, EarlyView.
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat, Priyanka Khatri, Youssif M. Ali, Chanuka H. Arachchilage, Gregory Demopulos, Kirsten Baillie, Kelly L. Miners, Kristin Ladell, Samantha A. Jones, Helen E. Davies, David A. Price, Wioleta M. Zelek, B. Paul Morgan, Wilhelm J. Schwaeble, Nicholas J. Lynch   +14 more
wiley   +1 more source

Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining [PDF]

, 2017
This work was supported by the European Commission within the FP7 Framework Programme [Fungitect-Grant No 602125]. We also thank Thomas Sauer, Vienna Biocenter Campus (VBC), Austria, for technical support at the FACS facility of the MFPL, Karl Kuchler ...
Gow, N, Istel, F, Jenull, S, Lion, T, Nogueira, MF, Walker, L A   +5 more
core   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source