Results 51 to 60 of about 6,162 (208)

Sterile Inflammation of Brain, due to Activation of Innate Immunity, as a Culprit in Psychiatric Disorders

Frontiers in Psychiatry, 2018
Evidence has accumulated that the occurrence of psychiatric disorders is related to chronic inflammation. In support of this linkage, changes in the levels of circulating pro-inflammatory cytokines and chemokines in the peripheral blood (PB) of ...
Mariusz Z. Ratajczak, Mariusz Z. Ratajczak, Daniel Pedziwiatr, Monika Cymer, Magda Kucia, Magda Kucia, Jolanta Kucharska-Mazur, Jerzy Samochowiec   +7 more
doaj   +1 more source

Dissection of the anti-Candida albicans mannan immune response using synthetic oligomannosides reveals unique properties of β-1,2 mannotriose protective epitopes

Scientific Reports, 2021
Candida albicans mannan consists of a large repertoire of oligomannosides with different types of mannose linkages and chain lengths, which act as individual epitopes with more or less overlapping antibody specificities. Although anti-C.
Boualem Sendid, Karine Lecointe, Mayeul Collot, Pierre-Marie Danzé, Sébastien Damiens, Anne-Sophie Drucbert, Chantal Fradin, Jean-Pierre Vilcot, Frédéric Grenouillet, Faustine Dubar, Jérôme de Ruyck, Samir Jawhara, Jean-Maurice Mallet, Daniel Poulain   +13 more
doaj   +1 more source

A Novel Pathosystem With the Model Plant Arabidopsis thaliana for Defining the Molecular Basis of Taphrina Infections

Environmental Microbiology Reports, Volume 17, Issue 3, June 2025.
A Taphrina strain, identified as Taphrina tormentillae, was shown to cause disease symptoms on the genetic model plant Arabidopsis thaliana, from which it was isolated. A genetic approach was used to implicate the known co‐receptor BAK1 in the activation of immune responses by likely PAMPs found in T. tormentillae cell walls.
Agate Auzane, Margaretta Christita, Kai Wang, Timo Sipilä, Sitaram Rajaraman, Gugan Eswaran, Jasmin Kemppinen, Alejandro De La Fuente, Klaas Bouwmeester, Petri Auvinen, Lars Paulin, Jarkko Salojärvi, Maija Sierla, Mikael Broché, Kirk Overmyer   +14 more
wiley   +1 more source

Differential activity of a lectin from Solieria filiformis against human pathogenic bacteria

Brazilian Journal of Medical and Biological Research, 2005
A lectin isolated from the red alga Solieria filiformis was evaluated for its effect on the growth of 8 gram-negative and 3 gram-positive bacteria cultivated in liquid medium (three independent experiments/bacterium).
M.L. Holanda, V.M.M. Melo, L.M.C.M. Silva, R.C.N. Amorim, M.G. Pereira, N.M.B. Benevides   +5 more
doaj   +1 more source

Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model

Frontiers in Immunology, 2022
BackgroundComplement lectin pathway components, in particular mannan-binding lectin (MBL) and MBL-associated serine proteases (MASPs) have been shown to interact with coagulation factors and contribute to clot formation.
Murielle Golomingi, Jessie Kohler, Lorenz Jenny, Elaissa T. Hardy, József Dobó, Péter Gál, Gábor Pál, Bence Kiss, Wilbur A. Lam, Verena Schroeder   +9 more
doaj   +1 more source

Exploring the Role of Pattern Recognition Receptors as Immunostimulatory Molecules

Immunity, Inflammation and Disease, Volume 13, Issue 5, May 2025.
This mini‐review summarizes different classes of pattern recognition receptors (PRRs) and the role of their agonizts that have been identified and also outlines the role of PRR ligands as immunostimulatory molecules. Overall, the mini‐review has elaborated on the role of PRRs in the development of therapeutic vaccine adjuvants.
Meenal Sharma, Priyanka Wagh, Tanvi Shinde, Diptee Trimbake, Anuradha S. Tripathy   +4 more
wiley   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide

BMC Immunology, 2011
Background Mannan-binding lectin (MBL) is a pattern-recognition molecule present in serum, which is involved in the innate immune defense by activating complement and promoting opsonophagocytosis. Dendritic cells (DCs) are professional antigen presenting
Zhang Liyun, Chen Yue, Zhang Yani, Wang Mingyong, Lu Xiao, Chen Zhengliang   +5 more
doaj   +1 more source

MASP-1 induces a unique cytokine pattern in endothelial cells: a novel link between complement system and neutrophil granulocytes. [PDF]

PLoS ONE, 2014
Microbial infection urges prompt intervention by the immune system. The complement cascade and neutrophil granulocytes are the predominant contributors to this immediate anti-microbial action.
Péter K Jani, Erika Kajdácsi, Márton Megyeri, József Dobó, Zoltán Doleschall, Krisztina Futosi, Csaba I Tímár, Attila Mócsai, Veronika Makó, Péter Gál, László Cervenak   +10 more
doaj   +1 more source

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden, Raquel Alonso‐Román, Johannes Stallhofer, Mark S. Gresnigt, Bernhard Hube, Alexander S. Mosig   +5 more
wiley   +1 more source