Role of Mannose-binding Lectin and Association with Microbial Sensitization in a Cohort of Patients with Atopic Dermatitis [PDF]
Acta Dermato-Venereologica, 2023 Atopic dermatitis is a relapsing inflammatory skin condition, in which bacteria, fungi and viruses may colonize the skin and aggravate the condition. Mannose-binding lectin is part of the innate immune system.
Emma Belfrage +6 more
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Lectin-like bacteriocins from Pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor. [PDF]
PLoS Pathogens, 2014 Lectin-like bacteriocins consist of tandem monocot mannose-binding domains and display a genus-specific killing activity. Here we show that pyocin L1, a novel member of this family from Pseudomonas aeruginosa, targets susceptible strains of this species ...
Laura C McCaughey +12 more
doaj +9 more sources
What contributes to an effective mannose recognition domain? [PDF]
Beilstein Journal of Organic Chemistry, 2017 In general, carbohydrate–lectin interactions are characterized by high specificity but also low affinity. The main reason for the low affinities are desolvation costs, due to the numerous hydroxy groups present on the ligand, together with the typically ...
Christoph P. Sager +4 more
doaj +4 more sources
Influence of the presence of mannose-binding lectin polymorphisms on the occurrence of leishmaniasis: a systematic review and meta-analysis [PDF]
Anais Brasileiros de Dermatologia, 2022 Background Leishmaniasis is caused by an intracellular protozoan of the Leishmania genus. Mannose-binding lectin (MBL) is a serum complement protein and recognizes lipoprotein antigens in protozoa and the bacterial plasma membrane. Nucleotide variants in
Wonei de Seixas Vital +5 more
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Activity of Mannose-Binding Lectin on Bacterial-Infected Chickens—A Review [PDF]
Animals, 2021 In recent years, diseases caused by pathogenic bacteria have profoundly impacted chicken production by causing economic loss in chicken products and by-product revenues. MBL (mannose-binding lectin) is part of the innate immune system (IIS), which is the
Peter A. Idowu +6 more
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Mannose binding lectin is required for alphavirus-induced arthritis/myositis. [PDF]
PLoS Pathogens, 2012 Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Bronwyn M Gunn +10 more
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Echinococcus multilocularis Calreticulin Inhibits Lectin Pathway of Complement Activation by Directly Binding to Mannose-Binding Lectin [PDF]
PathogensAlveolar Echinococcosis (AE) is a serious zoonotic disease caused by infection of Echinococcus multilocularis larvae. To survive within the host, E. multilocularis has developed a complex immune evasion mechanism including the inhibition of complement ...
Yuxiao Shao +8 more
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Cells, 2021 Betacoronaviruses, responsible for the “Severe Acute Respiratory Syndrome” (SARS) and the “Middle East Respiratory Syndrome” (MERS), use the spikes protruding from the virion envelope to attach and subsequently infect the host cells.
Annick Barre +7 more
doaj +1 more source
Structural determinants for activity and specificity of the bacterial toxin LlpA. [PDF]
PLoS Pathogens, 2013 Lectin-like bacteriotoxic proteins, identified in several plant-associated bacteria, are able to selectively kill closely related species, including several phytopathogens, such as Pseudomonas syringae and Xanthomonas species, but so far their mode of ...
Maarten G K Ghequire +5 more
doaj +1 more source
Cell-surface protein YwfG of Lactococcus lactis binds to α-1,2-linked mannose
PLoS ONE, 2023 Lactococcus lactis strains are used as starter cultures in the production of fermented dairy and vegetable foods, but the species also occurs in other niches such as plant material. Lactococcus lactis subsp. lactis G50 (G50) is a plant-derived strain and
Wataru Tsuchiya +7 more
doaj +2 more sources