Results 141 to 150 of about 71,841 (307)

Association of Selective Antibody Deficiency in Patients with Mannose-Binding Lectin Deficiency [PDF]

, 2010
Douglas R. Lotz, Alan P. Knutsen
openalex   +1 more source

Patterns of Mannose-Binding Lectin (MBL) responses to <i>Plasmodium falciparum</i> infections in hyperendemic settings

, 2023
Dia Aldeen Alfaki, M. M. Hussein, Amanda Elgoraish, Mohamed Mubarak Elbasheir   +3 more
openalex   +2 more sources

Simultaneous Grafting of 3,4,5‐Trihydroxypiperidine Iminosugars Onto Multivalent Scaffolds via Double Reductive Amination Provides New GCase Inhibitors

Chemistry – A European Journal, Volume 32, Issue 2, 9 January 2026.
A small set of low‐valency multivalent 3,4,5‐trihydroxypiperidines was prepared through double reductive amination (DRA) of a sugar‐derived dialdehyde. Among them, trivalent derivative 37 emerged as a potent β‐glucocerebrosidase (GCase) inhibitor displaying an unexpected mixed‐type kinetic profile. The integration of kinetic analysis, NMR, docking, and
Maria Giulia Davighi, Francesca Clemente, Alessio Morano, Francesca Mangiavacchi, Francesca Cardona, Andrea Goti, Paolo Paoli, Amelia Morrone, Ferran Nieto‐Fabregat, Roberta Marchetti, Camilla Matassini   +10 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Mannose-binding lectin gene polymorphism in psoriasis and vitiligo: an observational study and computational analysis. [PDF]

Front Med (Lausanne), 2023
Behairy MY, Tawfik NZ, Eid RA, Nasser Binjawhar D, Alshaya DS, Fayad E, Elkhatib WF, Abdallah HY.   +7 more
europepmc   +1 more source

Erratum: Association of polymorphisms in the mannose-binding lectin gene and pulmonary morbidity in preterm infants [PDF]

, 2008
Anne Hilgendorff, K Heidinger, A Pfeiffer, A Bohnert, Inke R. König, Andreas Ziegler, C Merz, G Frey, T Chakraborty, L Gortner, G Bein   +10 more
openalex   +1 more source

Glycan‐Mediated Grafting of Extracellular Matrix Proteins for Stable Biofunctionalization of Polystyrene Surfaces

Advanced Materials Interfaces, Volume 13, Issue 1, 7 January 2026.
We present a glycan‐mediated strategy for covalent grafting of extracellular matrix proteins onto polystyrene surfaces. This approach preserves protein bioactivity and enhances cell adhesion and viability. Using fibronectin and vitronectin, we demonstrate stable immobilization via glycosylation sites, offering a promising route for advanced ...
Mathilde Hindié, Damien Seyer, Ousmane Ba, Anthony C. Duncan, Arnaud Ponche, Olivier Gallet, Karine Anselme   +6 more
wiley   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source

Mannose-Binding Lectin 2 as a Potential Therapeutic Target for Hepatocellular Carcinoma: Multi-Omics Analysis and Experimental Validation. [PDF]

Cancers (Basel), 2023
Liao H, Yang J, Xu Y, Xie J, Li K, Chen K, Pei J, Luo Q, Pan M.   +8 more
europepmc   +1 more source

Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9.

, 2008
The role of Toll-like receptors (TLR) and MyD88 for immune responses to Mycobacterium tuberculosis (Mtb) infection remains controversial. To address the impact of TLR-mediated pathogen recognition and MyD88-dependent signaling events on anti ...
Abel, Bafica, Blander, Branger, Brightbill, Carroll, Cooper, Drennan, Feng, Flynn, Flynn, Fremond, Fremond, Gilleron, Gutierrez, Han, Holscher, Holscher, Hsieh, Jones, Kamath, Kaufmann, Kaufmann, Kawai, Krieg, MacMicking, MacMicking, Maher, Martinon, Means, Means, Means, Medzhitov, North, Quesniaux, Rausch, Reiling, Ryffel, Scanga, Scanga, Schaible, Seki, Shi, Shi, Shim, Sugawara, Sugawara, Sun, Takeuchi, Thoma-Uszynski, Trinchieri, Underhill, van der Wel, Yates   +53 more
core   +1 more source