Results 151 to 160 of about 89,044 (334)

The Landscape of SPP1+ Macrophages Across Tissues and Diseases: A Comprehensive Review

Immunology, EarlyView.
SPP1+ macrophages represent a conserved, disease‐associated population present across cancerous and non‐cancerous conditions, involved in immunosuppression, fibrosis, lipid metabolism, phagocytosis, and other cellular processes. This review highlights their shared molecular programmes across tissues, their interactions with stromal and immune cells ...
Alessandro Palma
wiley   +1 more source

Mannose binding lectin polymorphisms in systemic lupus erythematosus in Spain

European Journal of Inflammation, 2016
Low mannose binding lectin (MBL) producer genotypes have been considered as a systemic lupus erythematosus (SLE) risk factor. The aim of this study was to explore whether polymorphisms in the MBL gene are associated with susceptibility to SLE and disease-
Inés Losada López, Mercedes García Gasalla, Juan González Moreno, Araceli Serrano, Francisco Javier Domínguez Valdés, Joan Milà, Antoni Payeras   +6 more
doaj   +1 more source

Neutrophils in the Bone Marrow Express DEC205, Guiding Their Migration to Inflamed Tissues

Immunology, EarlyView.
In bone marrow, immature neutrophils express high levels of DEC205, necessary to mediate migration through endothelial cell layers in vitro and in vivo. During maturation and migration to peripheral tissues, expression of DEC205 is downregulated. Thus, expression of DEC205 inversely correlates with the maturation of neutrophils and is involved in ...
Shiying Jin, Xuan Lei, Sonali Singh, Alexander Enk, Karsten Mahnke   +4 more
wiley   +1 more source

Mannose-binding lectin levels and MBL2 gene polymorphisms are associated with dengue infection in Brazilian children at the early ages

International Journal of Infectious Diseases, 2022
Background: The mannose-binding lectin (MBL) plays an important role in innate immunity. Genetically determined variations in serum levels of MBL may influence the susceptibility and clinical outcome of dengue infection in early life.
Marília A. Sena, Priscila Mayrelle da Silva Castanha, Ana Beatriz Giles Guimarães, Paula Alexandra dos Santos Oliveira, Maria Almerice Lopes da Silva, Marli Tenório Cordeiro, Patricia Moura, Cynthia Braga, Luydson Richardson Silva Vasconcelos   +8 more
doaj  

The Pepper Mannose-Binding Lectin Gene CaMBL1 Is Required to Regulate Cell Death and Defense Responses to Microbial Pathogens1[C][W][OA]

Plant Physiology, 2011
Plant mannose-binding lectins (MBLs) are crucial for plant defense signaling during pathogen attack by recognizing specific carbohydrates on pathogen surfaces. In this study, we isolated and functionally characterized a novel pepper (Capsicum annuum) MBL
I. Hwang, B. Hwang
semanticscholar   +1 more source

Mechanisms governing bacterial capsular polysaccharide attachment and chain length

Annals of the New York Academy of Sciences, EarlyView.
Abstract Capsular polysaccharides (CPSs) are high‐molecular weight glycopolymers that form a capsule layer on the surface of many bacterial species. This layer serves as a crucial barrier between bacteria and their environment, protecting them from host immune responses and environmental stressors while facilitating adaptation to host niches.
Saroj Khadka, Emily L. Kinney, Brooke E. Ryan, Laura A. Mike   +3 more
wiley   +1 more source

Fast and Autonomous Mannosylated Nanomotors for Dynamic Cancer Cell Targeting

Angewandte Chemie, Volume 137, Issue 23, June 2, 2025.
An enzyme‐loaded nanomotor decorated with mannose polymers shows a synergistic effect with respect to cell targeting. The mannose units interact with mannose receptors (MRs) on the cell surface, whereas the presence of the glycopolymer on the motor surface also leads to a more effective motile behavior in cell medium. Abstract An attractive strategy in
Yuechi Liu, Roberto Terracciano, Jari Scheerstra, Gokhan Yilmaz, Hanglong Wu, Pascal Welzen, Shoupeng Cao, Tania Patino Padial, Loai Abdelmohsen, Jingxin Shao, Bingbing Sun, C. Remzi Becer, Jan C. M. van Hest   +12 more
wiley   +2 more sources

Griffithsin Retains Anti-HIV-1 Potency with Changes in gp120 Glycosylation and Complements Broadly Neutralizing Antibodies PGT121 and PGT126. [PDF]

, 2019
Griffithsin (Grft) is an antiviral lectin that has been shown to potently inhibit HIV-1 by binding high-mannose N-linked glycosylation sites on HIV-1 gp120.
Fischer, Kathryn, LiWang, Patricia J, Nguyen, Kimberly   +2 more
core  

Mannose‐Binding Lectin Plasma Levels and Gene Polymorphisms inPlasmodium falciparumMalaria [PDF]

, 1998
Adrian J. F. Luty, Jürgen F. J. Kun, Peter G. Kremsner   +2 more
openalex   +1 more source

A novel approach to enhance resistance to vascular disease by expressing cell‐death‐inducing fungal elicitors in the xylem tissue

Plant Biotechnology Journal, EarlyView.
Summary Constitutive expression of hypersensitive cell‐death‐inducing effectors secreted by pathogens has proved to be difficult in plants. Herein, xylem‐specific promoters (PVND7 or PVND2) were utilized to express three cell‐death‐inducing proteins (FocSIX1A, FocSIX6 or TvSm1) of fungal origin in banana plants.
Sanjana Negi, Himanshu Tak, Subham Bhakta, Mahesh Tiwari, Thumballi Ramabhatta Ganapathi, Sudhir Singh, Anand Ballal   +6 more
wiley   +1 more source