Results 11 to 20 of about 89,044 (334)

Echinococcus multilocularis Calreticulin Inhibits Lectin Pathway of Complement Activation by Directly Binding to Mannose-Binding Lectin [PDF]

Pathogens
Alveolar Echinococcosis (AE) is a serious zoonotic disease caused by infection of Echinococcus multilocularis larvae. To survive within the host, E. multilocularis has developed a complex immune evasion mechanism including the inhibition of complement ...
Yuxiao Shao, Meng Xia, Yinghui Song, Yan Yan, Xiaofang Dong, Haoran Zong, Bin Zhan, Yanhai Wang, Limei Zhao   +8 more
doaj   +2 more sources

Undetectable mannose binding lectin is associated with HRCT proven bronchiectasis in rheumatoid arthritis (RA). [PDF]

PLoS ONE, 2019
AimThe aim of this study was to ascertain whether mannose binding lectin deficiency is implicated in coexistent rheumatoid arthritis and bronchiectasis and to determine whether undetectable mannose binding lectin confers poorer long-term survival in ...
Krista Makin, Tracie Easter, Monica Kemp, Peter Kendall, Max Bulsara, Sophie Coleman, Graeme J Carroll   +6 more
doaj   +4 more sources

What contributes to an effective mannose recognition domain? [PDF]

Beilstein Journal of Organic Chemistry, 2017
In general, carbohydrate–lectin interactions are characterized by high specificity but also low affinity. The main reason for the low affinities are desolvation costs, due to the numerous hydroxy groups present on the ligand, together with the typically ...
Christoph P. Sager, Deniz Eriş, Martin Smieško, Rachel Hevey, Beat Ernst   +4 more
doaj   +4 more sources

The role of mannose-binding lectin in pneumococcal infection [PDF]

European Respiratory Journal, 2012
The role of mannose-binding lectin (MBL) deficiency (MBL2;XA/OandO/Ogenotypes) in host defences remains controversial. The surfactant proteins (SP)-A1, -A2 and -D, other collectins whose genes are located nearMBL2, are part of the first-line lung defence against infection.
Miguel A. García-Bello, Judith Noda, Olga Rajas, Jordi Rello, Jordi Solé-Violán, Felipe Rodríguez de Castro, Estefanía Herrera-Ramos, Carlos Rodríguez-Gallego, J. Alberto Marcos-Ramos, Antoni Payeras, Javier Aspa, José Blanquer, Luis Borderías, M. Luisa Briones, M. Isabel García-Laorden, Jose M. Ferrer   +15 more
openaire   +5 more sources

Mannose-Binding Lectin Promoter Polymorphisms and Gene Variants in Pulmonary Tuberculosis Patients from Cantabria (Northern Spain)

Pulmonary Medicine, 2012
Mannose-binding lectin is a central molecule of the innate immune system. Mannose-binding lectin 2 promoter polymorphisms and structural variants have been associated with susceptibility to tuberculosis.
J.-Gonzalo Ocejo-Vinyals, Lucía Lavín-Alconero, Pablo Sánchez-Velasco, M.-Ángeles Guerrero-Alonso, Fernando Ausín, M.-Carmen Fariñas, Francisco Leyva-Cobián   +6 more
doaj   +2 more sources

Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease

International Journal of COPD, 2012
Richard K Albert,1 John Connett,2 Jeffrey L Curtis,3,4 Fernando J Martinez,3 MeiLan K Han,3 Stephen C Lazarus,5 Prescott G Woodruff51Medicine Service, Denver Health and Department of Medicine, University of Colorado Denver, Denver, CO, 2Division of ...
Woodruff PG, Lazarus SC, Han MK, Martinez FJ, Curtis JL, Connett J, Albert RK   +6 more
doaj   +2 more sources

A Novel High-Mannose Specific Lectin from the Green Alga Halimeda renschii Exhibits a Potent Anti-Influenza Virus Activity through High-Affinity Binding to the Viral Hemagglutinin

Marine Drugs, 2017
We have isolated a novel lectin, named HRL40 from the green alga Halimeda renschii. In hemagglutination-inhibition test and oligosaccharide-binding experiment with 29 pyridylaminated oligosaccharides, HRL40 exhibited a strict binding specificity for high-
Jinmin Mu, Makoto Hirayama, Yuichiro Sato, Kinjiro Morimoto, Kanji Hori   +4 more
doaj   +2 more sources

Mannose-binding lectin gene sequence data in Kelantan population [PDF]

Scientific Data
The human mannose-binding lectin (MBL) gene encodes a polymorphic protein that plays a crucial role in the innate immune response. Human MBL deficiency is associated with immunodeficiencies, and its variants have been linked to autoimmune and infectious ...
Muhamad Aidil Zahidin, Noor Haslina Mohd Noor, Muhammad Farid Johan, Abu Dzarr Abdullah, Zefarina Zulkafli, Hisham Atan Edinur   +5 more
doaj   +2 more sources

Mannose binding lectin

Archives of Disease in Childhood, 2001
ARCHIVIST
openalex   +3 more sources

Status of mannose-binding lectin (MBL) and complement system in COVID-19 patients and therapeutic applications of antiviral plant MBLs

Molecular and Cellular Biochemistry, 2021
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by a virus called “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).” In the majority of patients, infection with COVID-19 may be asymptomatic or may cause only mild symptoms.
Anita Gupta, G. Gupta
semanticscholar   +1 more source