Results 11 to 20 of about 71,841 (307)

Mannose-binding lectin may affect pregnancy outcome

The Turkish Journal of Pediatrics, 2015
Mannose-binding lectin (MBL) is a component of the innate immune system and acts as a complement activator through the lectin pathway. Genetic variations of MBL and low MBL levels cause several infection problems, which may also be related to ...
Şebnem Çalkavur, Fuat Akercan, Ferda Özkınay, Güzide Aksu, Osman Zekioğlu, Mehmet Yalaz, Özge Altun Köroğlu, Hüseyin Onay, Gülin Erdemir, Nilgün Kültürsay   +9 more
doaj   +3 more sources

COVID-19 Recurrence Without Seroconversion in a Patient With Mannose-Binding Lectin Deficiency

Allergy & Rhinology, 2021
Introduction The SARS-CoV-2 virus has infected more than 63,000,000 people worldwide after emerging from Wuhan, China in December 2019. This outbreak was declared a Public Health Emergency in January 2020, and a pandemic in March. While rare, reinfection
Breanne Hayes DO, Jonathan Stanley DO, Brian P. Peppers DO, PhD   +2 more
doaj   +1 more source

Isolation and partial characterisation of a novel lectin from Aegle marmelos fruit and its effect on adherence and invasion of Shigellae to HT29 cells. [PDF]

PLoS ONE, 2011
Lectins are a class of ubiquitous proteins/glycoproteins that are abundantly found in nature. Lectins have unique carbohydrate binding property and hence have been exploited as drugs against various infectious diseases.
Subramaniya Bharathi Raja, Malliga Raman Murali, Nirmal Kasinathan Kumar, Sivasitambaram Niranjali Devaraj   +3 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300 [PDF]

, 2016
To characterize the interaction potential of the human vaginal isolate Lactobacillus plantarum CMPG5300, its genome was mined for genes encoding lectin-like proteins.
Balzarini, Jan, Imholz, Nicole CE, Lebeer, Sarah, Liekens, Sandra, Malik, Shweta, Noppen, Sam, Petrova, Mariya I, Schols, Dominique, Van Damme, Els, Vanderleyden, Jos, Verhoeven, Tine LA   +10 more
core   +1 more source

Mannose‐binding lectin and gastric cancer [PDF]

International Journal of Cancer, 2007
Daniel L. Worthley*, Peter G. Bardy, David L. Gordon and Charles G. Mullighan Department of Gastroenterology and Hepatology, Flinders Medical Centre, South Australia, Australia Division of Hematology, Royal Adelaide Hospital and Institute of Medical and Veterinary Science, South Australia, Australia Department of Hematology–Oncology, The Queen ...
Worthley, D., Bardy, P., Gordon, D., Mullighan, C.   +3 more
openaire   +3 more sources

Mannose-binding lectin levels and major infections in a cohort of very long-term survivors after allogeneic stem cell transplantation

Haematologica, 2010
Background Life-threatening infections are a major cause of death after allogeneic stem cell transplantation. Complement Mannose-binding lectin is a key component of innate immunity.
Michael Osthoff, Alicia Rovó, Martin Stern, Doris Danner, Alois Gratwohl, André Tichelli, Marten Trendelenburg   +6 more
doaj   +1 more source

High glucose disrupts oligosaccharide recognition function via competitive inhibition : a potential mechanism for immune dysregulation in diabetes mellitus [PDF]

, 2011
Diabetic complications include infection and cardiovascular disease. Within the immune system, host-pathogen and regulatory host-host interactions operate through binding of oligosaccharides by C-type lectin.
Ahmed, Bee K. Tan, Botto, Bouyain, Caparros, Carlow, Ceriello, Chaipan, Daniel A. Mitchell, Daniel Zehnder, Devaraj, Elizabeth J. Soilleux, Feinberg, Fernandez-Real, Geijtenbeek, Geijtenbeek, Geijtenbeek, Ghanim, Gringhuis, Guo, Harpal S. Randeva, Held, Hendrik Lehnert, Holman, Ip, Krutzik, Lee, Lillegard, Mitchell, Moller-Kristensen, Nauta, Paidassi, Paul Townsend, Permana, Pohlmann, Reading, Rebecca Ilyas, Robert B. Sim, Russell Wallis, Savill, Schilder, Seelen, Soilleux, Strong, Stuart, Turner, Turner, UKPDS, Wallis, Walport, Walport, Weis, Weis, Worthley, Zeyda   +54 more
core   +1 more source

Evaluation of the cytokine mannose-binding lectin as a mediator of periportal fibrosis progression in patients with schistosomiasis

Revista da Sociedade Brasileira de Medicina Tropical, 2015
INTRODUCTION : We hypothesized higher mannose-binding lectin level and classic factors (i.e., age, sex, alcohol consumption, exposure, and specific treatment) are associated with the severity of periportal fibrosis in schistosomiasis.
Paula Carolina Valença Silva, Adriana Vieira Gomes, Georgea Gertrudes de Oliveira Mendes Cahu, Maria Rosângela Cunha Duarte Coêlho, Maria Tereza Cartaxo Muniz, Ana Lúcia Coutinho Domingues   +5 more
doaj   +1 more source

Optimisation of the enzyme-linked lectin assay for enhanced glycoprotein and glycoconjugate analysis [PDF]

, 2011
Lectin’s are proteins capable of recognising and binding to specific oligosaccharide tructures found on glycoproteins and other biomoloecules. As such they have found tility for glycoanalytical applications.
Afrough, Aileen Creavin, Ambrosi, Andrews, Brendan O’Connor, Campbell, Charlwood, Chen, Debray, Drickamer, Duk, Dwek, Eisen, Geyer, Guile, Harvey, Hsu, Huber, Iskratsch, Jiménez-Barbero, Karamanska, Karlsson, Kim, Kirkeby, Kristiansen, Laemmli, Lis, Loris, Michael O’Connell, North, Olausson, Paul Clarke, Pilobello, Pilobello, Raman, Roisin Thompson, Rosenfeld, Royle, Rudd, Rudd, Rudd, Sparbier, Studentsov, Trimble, Varki, Wu, Wu, Wu, Wu   +48 more
core   +2 more sources