Results 241 to 250 of about 82,856 (307)

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

The FEBS Journal, EarlyView.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher, Pavel Dobeš, Jan Komárek, Lukáš Faltinek, Marek Korsák, Petra Sýkorová, Josef Houser, Michaela Wimmerová   +7 more
wiley   +1 more source

Anti‐melanogenic effects of Medicago sativa seed extracts on melanocytes

International Journal of Cosmetic Science, EarlyView.
Our study demonstrated that two types of alfalfa seed extract: alfalfa ethanol precipitate (AEP) and alfalfa ethanol supernatant (AES) inhibited melanogenesis through the downregulation of tyrosinase expression, following the inactivation of CREB, b‐catenin and ERK signalling pathway in α‐melanocyte‐stimulating hormone (α‐MSH)‐stimulated B16F10 mouse ...
Chae Rin Kim, Jung Woo, Kyu Lim Kim, Minah Choi, Hee Jung Shin, Junoh Kim, Kyung Min Lim, Chang‐Seok Lee   +7 more
wiley   +1 more source

Use of Dermocosmetics in Acne Management: A Middle East‐North Africa Consensus

International Journal of Dermatology, EarlyView.
ABSTRACT Background Acne in the Middle East and Northern Africa (MENA) is associated with high rates of post‐inflammatory hyperpigmentation and scarring, resulting from relatively high frequencies of darker or oily skin types, environmental factors, perceptions, and knowledge of acne and its treatment.
Sameer Zimmo, Hesham Zaher, Amal Said, Eman El Morsy, Noureddine Litaiem, Anwar Al Hammadi, Amal El Sayed, Martin Steinhoff   +7 more
wiley   +1 more source

Multiomics Comparison of Proline‐Rich Peptide‐Enhanced Hyaluronic Acid Gels Versus Conventional Regenerative Materials: An Early Wound‐Healing Model

Journal of Periodontal Research, EarlyView.
A proline‐rich peptide (P6) embedded in crosslinked hyaluronic acid replicates EMD's early anti‐inflammatory and proremodelling signature in a porcine gingival model, highlighting a fully synthetic, ethically sound candidate for periodontal regeneration.
Øystein Øvrebø, Ståle Petter Lyngstadaas, Thaqif El Khassawna, Reem Jamous, Qianli Ma, Fernando Muñoz, Maria Permuy, Antonio Gonzalez Cantalapiedra, Antonio José Serrano‐Muñoz, Joana Maria Ramis, Marta Monjo, Filippo Rossi, Håvard J. Haugen   +12 more
wiley   +1 more source

Enterococcus proliferates via the phosphotransferase system in the disrupted gut microbiota after allogeneic haematopoietic stem cell transplantation

British Journal of Haematology, EarlyView.
Akihisa Hino, Shinsuke Kusakabe, Kentaro Oka, Hayami Kudo, Tadashi Ariyoshi, Atsushi Hayashi, Motomichi Takahashi, Makoto Onizuka, Kiyoshi Takeda, Masaki Mori, Naoki Hosen, Kentaro Fukushima   +11 more
wiley   +1 more source

The Gfr Uptake System Provides a Context‐Dependent Fitness Advantage to Salmonella Typhimurium SL1344 During the Initial Gut Colonization Phase

Molecular Microbiology, EarlyView.
Diet–microbiota interactions shape colonization resistance. While the microbiota restricts pathogens like Salmonella through nutrient competition, Salmonella can exploit private nutrients such as fructoselysine (FL), abundant in processed foods but inaccessible to most microbes.
Lea Fuchs, Cora Lisbeth Dieterich, Elena Melgarejo Ros, Philipp Keller, Anna Sintsova, Leanid Laganenka, Thomas A. Scott, Christopher Schubert, Shinichi Sunagawa, Julia A. Vorholt, Jörn Piel, Wolf‐Dietrich Hardt, Bidong D. Nguyen   +12 more
wiley   +1 more source

Memory in the wall: expanding our understanding of the roles of plant cell walls

New Phytologist, EarlyView.
Summary The plant cell wall, while providing mechanical support to cells, also dynamically adjusts its composition and structure in response to cellular and environmental cues. Recent findings indicate that plants exposed to cold stress alter the composition of cell wall polysaccharides and that this altered status primes the plants to overcome future,
Hiromasa Shikata, Akira Yoshinari, Mariko Asaoka, Daisuke Takahashi   +3 more
wiley   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

Highly efficient transgene‐free ErCas12a RNP‐protoplast genome editing and single‐cell regeneration in Nicotiana benthamiana for glyco‐engineering

Plant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana serves as a unique platform for biopharmaceutical production, offering advantages such as efficient and scalable protein synthesis. In addition, custom N‐glycans can be engineered on biopharmaceutical glycoproteins. Yet, plant‐native glycosyltransferases and glycoside hydrolases need to be removed to prevent undesired ...
Lukas C. Blumberg, Geartsje M. Bakker, Alex van der Kaaij, Élyse Gariépy, Henri van de Geest, Erik J. Slootweg, Ferdinand C. O. Los, Lotte B. Westerhof, Ruud H. P. Wilbers   +8 more
wiley   +1 more source