Results 271 to 280 of about 2,479,436 (371)

Taxonomic and functional shifts in the microbiome of severely obese, prediabetic patients: Ketogenic diet versus energy‐matched standard diet

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Obesity and type 2 diabetes mellitus (T2DM) are among the leading global health challenges of the 21st century. While caloric restriction remains the cornerstone of weight loss interventions, ketogenic diets (KD), characterised by low carbohydrate and high fat intake, have been shown to improve metabolic health partly by modulating the ...
June Stone, Afroditi Tripyla, Melanie C. Scalise, Maria L. Balmer, Lia Bally, Dominik M. Meinel   +5 more
wiley   +1 more source

A Role of Rab29 in the Integrity of the Trans-Golgi Network and Retrograde Trafficking of Mannose-6-Phosphate Receptor

, 2014
Shicong Wang, Zexu Ma, Xiaohui Xu, Zhen Wang, Lixiang Sun, Yunhe Zhou, Xiaosi Lin, Wanjin Hong, Tuanlao Wang   +8 more
openalex   +1 more source

Beyond diabetes and obesity: GLP‐1 receptor agonists in disrupting the vicious cycle of metabolic dysfunction and neuroinflammation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Neurodegenerative diseases, including debilitating conditions like Alzheimer's and Parkinson's, are characterized by progressive neuronal loss, a process fundamentally driven by persistent chronic neuroinflammation and central metabolic dysfunction.
Renata Spezani, Carlos A. Mandarim‐de‐Lacerda   +1 more
wiley   +1 more source

Macrophages exploit the mannose receptor and JAK-STAT1-MHC-II pathway to drive antigen presentation and the antimycobacterial immune response after BCG vaccination. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Zhang Y, Xu D, Nie Q, Wang J, Fang D, Xie Y, Xiong H, Pan Q, Zhang XL.   +8 more
europepmc   +1 more source

Use of the oral microbiota as screening test to identify children at risk for caries development. A systematic review of longitudinal studies

European Journal of Oral Sciences, EarlyView.
Abstract This study investigated trends in oral microbiota composition (index test) that could indicate potential candidates to identify children at risk for dental caries development compared with visual/tactile examination (reference test). MEDLINE/PubMed, Web of Science, Embase, Scopus, Lilacs, SciELO, and Google Scholar databases were searched up ...
Heitor Sales de Barros Santos, Maria Eduarda Lisboa Pagnussatti, Marisa Maltz, Rodrigo Alex Arthur   +3 more
wiley   +1 more source

Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes [PDF]

, 2000
Shigeru Kawakami, Atsuo Sato, Makiya Nishikawa, Fumiyoshi Yamashita, Mitsuru Hashida   +4 more
openalex   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

C-Type Mannose Receptor 2 [PDF]

, 2020
openaire   +1 more source

Protein nanoparticles assemble in plants, display antigenic viral peptides, and produce an epitope‐specific immune response

The FEBS Journal, EarlyView.
Current methods to control porcine reproductive and respiratory syndrome, a disease affecting pigs, are insufficient and a safer, more effective vaccine is needed. This study describes the design and plant production of a self‐assembling protein nanoparticle vaccine candidate against this disease.
Jordan T. VanderBurgt, Richard Strasser, Hong Zhu, Angelo Kaldis, Christopher P. Garnham, Rima Menassa   +5 more
wiley   +1 more source

Mannose receptor targeted bioadhesive chitosan nanoparticles of clofazimine for effective therapy of tuberculosis. [PDF]

Saudi Pharm J, 2020
Pawde DM, Viswanadh MK, Mehata AK, Sonkar R, Narendra, Poddar S, Burande AS, Jha A, Jha A, Vajanthri KY, Mahto SK, Azger Dustakeer VN, Muthu MS.   +12 more
europepmc   +1 more source