Results 61 to 70 of about 82,856 (307)

Guides for Developing Hundreds of Novel Chiral MXenes and MBenes Nanosheets/Quantum Dots for Next‐Generation Chiral Engineered Biomaterials Applications

Advanced Healthcare Materials, EarlyView.
The emerging field of MXene/MBene materials has progressed rapidly, advancing diverse research fields, including biomedical engineering, biomedicine, agriculture, and the environment. This nanobiotechnology can tackle longstanding challenges in these areas.
Alireza Rafieerad, Ahmad Amiri
wiley   +1 more source

D-mannose suppresses the angiogenesis and progression of colorectal cancer

Acta Biochimica et Biophysica Sinica
Angiogenesis is an important factor influencing the development of solid tumors, and vascular endothelial growth factor receptor-2 (VEGFR2) is a central regulator of angiogenesis.
Du Yu, Zhang Xinchao, Xu Yixin, Zhou Yuefan, Xu Yanping   +4 more
doaj   +1 more source

Interactions between the mannose receptor and thyroid autoantigens

Clinical and Experimental Immunology, 2004
SummaryThyroid autoantigens require internalization and processing by antigen-presenting cells to induce immune responses. Besides pinocytosis, antigen uptake can be receptor-mediated. The mannose receptor (ManR) has a cysteine rich domain (CR) and eight carbohydrate recognition domains (CRD) that bind glycosylated proteins.
Jin Guo, Gregorio D. Chazenbalk, Pavel N. Pichurin, Sandra M. McLachlan, Basil Rapoport   +4 more
openaire   +4 more sources

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source

Gradients of Aliveness and Engineering: A Taxonomy of Fungal Engineered Living Materials

Advanced Materials, EarlyView.
This paper explores the potential of fungal engineered living materials (ELMs), examining fungal biology and growth mechanisms, which underpin their development. It presents a classification framework based on aliveness, scaffold composition, and engineering degree. Unique properties such as self‐healing, biosensing, and bioremediation are highlighted,
Elise Elsacker, Jara Saluena Martin, Annah‐Ololade Sangosanya, Anouk Verstuyft, Aurélie Van Wylick, Eveline Peeters   +5 more
wiley   +1 more source

Effect of differential N-linked and O-linked mannosylation on recognition of fungal antigens by dendritic cells.

PLoS ONE, 2007
BackgroundAn experimental approach for improving vaccine efficacy involves targeting antigens to mannose receptors (MRs) on dendritic cells (DCs) and other professional antigen presenting cells.
Jennifer S Lam, Haibin Huang, Stuart M Levitz   +2 more
doaj   +1 more source

Expression of mannose 6-phosphate receptors in chicken [PDF]

Developmental Dynamics, 1996
In mammals, the sorting of newly synthesized lysosomal enzymes is accomplished by two mannose 6-phosphate receptors (MPR) designated MPR46 and MPR300. MPR300 has an additional function in clearing the nonglycosylated insulin-like growth factor II (IGFII).
U. Matzner, Regina Pohlmann, Kurt von Figura, Annette Hille-Rehfeld   +3 more
openaire   +3 more sources

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

Advanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma, Chengke Xie, Chengyu Liao, Binting Huang, Siqi Liu, Junhua Kong, Xiaotong Fan, Zibiao Li, Shi Chen, Chaobin He   +9 more
wiley   +1 more source

Monosaccharide coating modulate the intracellular trafficking of gold nanoparticles in dendritic cellsKey findings

Materials Today Bio
Dendritic cells (DCs) have emerged as a promising target for drug delivery and immune modulation due to their pivotal role in initiating the adaptive immune response.
Meshal A. Alobaid, Sarah-Jane Richards, Morgan R. Alexander, Matthew I. Gibson, Amir M. Ghaemmaghami   +4 more
doaj   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source