Results 191 to 200 of about 1,043,830 (367)

In vivo regulation of MAP kinases in Ratus norvegicus renal papilla by water loading and restriction. [PDF]

, 1998
Paul A. Wojtaszek, Lynn E. Heasley, Tomás Berl   +2 more
openalex   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase.

, 1993
Takahito Itoh, Kozo Kaibuchi, Tomomi Masuda, Tadashi Yamamoto, Yoshiharu Matsuura, A. Maeda, Kazuo Shimizu, Yoshimi Takai   +7 more
openalex   +1 more source

Bombesin and zinc enhance the synergistic mitogenic effects of insulin and phosphocholine by a MAP kinase‐dependent mechanism in Swiss 3T3 cells [PDF]

, 1997
Zoltán Kiss, Karan S. Crilly, Masahiro Tomono   +2 more
openalex   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Activation of MEK‐1 and SEK‐1 by Tpl‐2 proto‐oncoprotein, a novel MAP kinase kinase kinase.

EMBO Journal, 1996
A. Salmeron, T. B. Ahmad, G. W. Carlile, Darryl J. Pappin, R. P. Narsimhan, Steven C. Ley   +5 more
semanticscholar   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation. [PDF]

, 1995
Xiaoyun Zhu, Richard K. Assoian
openalex   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Thyrotropin-releasing hormone stimulates MAP kinase activity in GH3 cells by divergent pathways. Evidence of a role for early tyrosine phosphorylation.

, 1994
M. Ohmichi, Takeshi Sawada, Yuki Kanda, Koji Koike, K. Hirota, Akira Miyake, Alan R. Saltiel   +6 more
openalex   +1 more source