Results 1 to 10 of about 322,191 (274)
Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Neobavaisoflavone (NBIF) is an isoflavone isolated from Psoralea corylifolia L. It can effectively regulate the redox state as a natural anti-oxidant and show some anti-inflammatory activity.
Qing Yuan +8 more
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Nimodipine promotes neurite outgrowth and protects against neurotoxicity in PC12 cells [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Nimodipine is an L-type voltage-dependent calcium channel (VDCC) antagonist. However, the actions of nimodipine except calcium blocking are poorly understood. This study aimed to investigate the effect of nimodipine on neurite outgrowth and
Miduki Kusakabe, Yasushi Hasegawa
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Acta Cirúrgica Brasileira, 2022 Purpose: The active melanocytes in the skin were affected by hormones and ultraviolet (UV) irradiation. Licorice zinc has a whitening effect, which may have a prominent potential in the treatment of pigmented skin disease.
Jing-yan Wang +6 more
doaj +1 more source
Journal of Fungi, 2022 Morphogenesis is a strictly regulated efficient system in eukaryotes for adapting to environmental changes. However, the morphogenesis regulatory mechanism in smut fungi is not clear.
Enping Cai +7 more
doaj +1 more source
Systems biology analysis of G protein and MAP kinase signaling in yeast [PDF]
Oncogene, 2007 Approximately a third of all drugs act by binding directly to cell surface receptors coupled to G proteins. Other drugs act indirectly on these same pathways, for example, by inhibiting neurotransmitter reuptake or by blocking the inactivation of intracellular second messengers. These drugs have revolutionized the treatment of human disease.
N, Hao +3 more
openaire +2 more sources
Scientific Reports, 2022 Coordinating the balance between development and stress responses is critical for organismal survival. However, the cellular signaling controlling this mechanism is not well understood.
Rose Aria Malinow +3 more
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Heregulin β-1 induces loss of cell-cell contact and enhances expression of MUC1 at the cell surface in HCC2998 and MKN45-1 cells. [PDF]
PLoS ONE, 2011 Signal transduction and cell responses after stimulation with heregulin β-1 (HRG) are examined in HCC2998 and MKN45-1 cells, which have been used for a model system to study the formation of signet ring carcinomas, one of poorly differentiated ...
Rintaro Okoshi +3 more
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Drug and Chemical Toxicology, 2021 Effects of Caffeic acid phenethyl ester (CAPE) and/or PD98059 (PD) on the gene expression of Caveolin-1 (CAV1) and reduced glutathione (GSH), malondialdehyde (MDA), copper-zinc superoxide dismutase (CuZn-SOD), and catalase (CAT) enzyme activities were investigated in an experimental chronic renal failure model in rats.
Ciğremiş, Yilmaz +4 more
openaire +4 more sources
Time courses of changes in phospho- and total- MAP kinases in the cochlea after intense noise exposure. [PDF]
PLoS ONE, 2013 Mitogen-activated protein kinases (MAP kinases) are intracellular signaling kinases activated by phosphorylation in response to a variety of extracellular stimuli.
Yukihide Maeda +4 more
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Mathematical modelling of the MAP kinase pathway using proteomic datasets. [PDF]
PLoS ONE, 2012 The advances in proteomics technologies offer an unprecedented opportunity and valuable resources to understand how living organisms execute necessary functions at systems levels.
Tianhai Tian, Jiangning Song
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