Results 151 to 160 of about 381,210 (291)

<i>Akkermansia muciniphila</i> alleviates antibiotic- and LPS-induced oxidative stress via the p38α MAPK-Nrf2 signaling axis. [PDF]

Front Microbiol
Ye WY, Feng CX, Su SQ, Wei SM, Mao Y, Chen ZY, Su Y, Shan QW.   +7 more
europepmc   +1 more source

Backbone 1H, 13C, and 15N Chemical Shift Assignments for p38 gamma MAPK

, 2016
Florence Cordier, Pierre Maisonneuve, Célia Caillet‐Saguy, Muriel Delepierre, Nicolas Wolff   +4 more
openalex   +1 more source

The Roles of PI3K/AKT/mTOR and MAPK/ERK Signaling Pathways in Human Pheochromocytomas [PDF]

, 2016
Juan Du, Anli Tong, Fen Wang, Yunying Cui, Chunyan Li, Yushi Zhang, Zhaoli Yan   +6 more
openalex   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

miR-214-3p Mediates Samarium Oxide-Induced Pulmonary Fibrosis by Targeting MAP2K3 via the MAPK Signaling Pathway. [PDF]

Toxics
Sun Y, Ding R, Yin H, Ma T, Bi Y, Li S, Wang L, Wang X.   +7 more
europepmc   +1 more source

HMG-XY REGULATES DRUG-RESISTANCE OF ACUTE MYELOID LEUKEMIA CELLS THROUGH MAPK PATHWAY

, 2019
Hui Zeng, Jue Li, Cheng Zhou
openalex   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

RETRACTED: Hwang et al. <i>Rosa davurica</i> Pall. Improves <i>Propionibacterium acnes</i>-Induced Inflammatory Responses in Mouse Ear Edema Model and Suppresses Pro-Inflammatory Chemokine Production via MAPK and NF-κB Pathways in HaCaT Cells. <i>Int. J. Mol. Sci.</i> 2020, <i>21</i>, 1717. [PDF]

Int J Mol Sci
Hwang DH, Lee DY, Koh PO, Yang HR, Kang C, Kim E.   +5 more
europepmc   +1 more source

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li, Li Chen, Tao Wang, Haiyang Jiang, Huijuan Wang, Mengyu Li, Guanpeng Xie, Chunhua Xi, Han Yan, Chunhui Lu, Chenchen Li, Hanyu Zhu, Feihu Sun, Lingdi Yin, Jun Yu, Yi Miao   +15 more
wiley   +1 more source

Folinic Acid Improves Healing of Diabetic Foot Ulcers. [PDF]

Wound Repair Regen
Hoke GD, Stone A, Bauer MA, Carter WC, Newsom MR, Boykin JV.   +5 more
europepmc   +1 more source