Results 101 to 110 of about 22,079 (225)
2023 06 05 Hippocapus total MAPT 11 43
, 2023 Detection of total MAPT species by digital droplet PCR in hippocampal samples of non-demented individuals and Alzheimer's disease ...Laura Vallés-Saiz (17122640), Daniel Ruiz-Gabarre (17122663), Jesus Avila (14484041), Vega García-Escudero (17021742) +3 morecore +1 more sourcePositive Carrier for MAPT
Alzheimer's & DementiaAbstractDementia was a condition I was aware of from a very young age as I witnessed my grandmother decline, and my mother step into the role as a caregiver, health care director and power of attorney. I was taught the foundation for this process by direct observation of my mother’s actions.openaire +1 more sourceA comprehensive analysis of MAPT-related genetic risk in Alzheimer’s disease
IBRO Neuroscience ReportsDespite some research into the correlation between microtubule associated protein tau (MAPT) rs2471738 and the risk of AD, the findings remain inconclusive.Shitao Wang, Guoshuai Luo, Xiangqian Ding, Guangxin Sun, Mengen Zhang, Jingjing Dong, Hui Xu, Jinghong Lu, Zongyou Li, Bin Ning, Hongbo Liu +10 moredoaj +1 more sourceGenetic Architecture of MAPT Gene Region in Parkinson Disease Subtypes.
Frontiers in Cellular Neuroscience, 2016 The microtubule-associated protein tau (MAPT) region has been conceptualized as a model of the interaction between genetics and functional disease outcomes in neurodegenerative disorders, such as Parkinson disease. Indeed, haplotype-specific differences Esterina ePascale, Maria Elena eDi Battista, Maria Elena eDi Battista, Alfonso eRubino, Alfonso eRubino, Carlo ePurcaro, Carlo ePurcaro, Marcella eValente, Marcella eValente, Francesco eFattapposta, Giampiero eFerraguti, Giuseppe eMeco, Giuseppe eMeco +12 moredoaj +1 more sourceThe Target48 Neurodegeneration panel: A novel tool for profiling protein signatures in neurodegenerative disorders
Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.Abstract INTRODUCTION
Novel tools for absolute quantification of established and emerging fluid neuro‐biomarkers are required to advance diagnostic studies and improve biological insights. METHODS
We conducted an extensive analytical and clinical validation of the Olink™ Target 48 Neurodegeneration panel (T48 Neuropanel) in 352 paired cerebrospinal ...Yanaika S. Hok‐A‐Hin, Lisa Vermunt, Natascha de Jong, Marta del Campo Milan, Everard Vijverberg, Afina W. Lemstra, Yolande Pijnenburg, Argonde C. van Harten, Charlotte E. Teunissen +8 morewiley +1 more sourceSpatiotemporal heterogeneity and dynamic evolution of microglial glucose metabolic reprogramming in Alzheimer's disease
Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.Abstract
Alzheimer's disease (AD) is accompanied by persistent disturbances in brain energy metabolism, and microglial glucose metabolic reprogramming constitutes an important link among pathological protein deposition, neuroinflammation, and impaired clearance.Yuan Chen, Fuyao Li, Junlei Zhang, Mingqing Wei, Jingnian Ni, Ting Li, Lulu Yao, Jinzhou Tian, Jing Shi +8 morewiley +1 more sourceFull sequencing and haplotype analysis of MAPT in Parkinson's disease and rapid eye movement sleep behavior disorder
, 2018 Background: MAPT haplotypes are associated with PD, but their association with rapid eye movement sleep behavior disorder is unclear. Objective: To study the role of MAPT variants in rapid eye movement sleep behavior disorder.Gagnon, J-F, Dauvilliers, Yves, Ross, Jay, Dan Spiegelman, Ruskey, Jennifer A., Bourassa, Cynthia V, Ambalavanan, A, Laurent, Sandra B., Nicolas Dupré, Jean-François Gagnon, Dupré, N, Laurent, Sandra B, Ferman, Tanis, Ruskey, Jennifer A, Antelmi, E, Postuma, Ronald B., Ross, Owen, Ferman, Tanis J., Charley Monaca, C, Ross, JP, Christelle Charley Monaca, Ferini-Strambi, Luigi, Yves Dauvilliers, Plazzi, G, Labbe, C, Desautels, A, Högl, B, Luigi Ferini-Strambi, Högl, Birgit, Young, Peter, Peter Young, Michele T.M. Hu, Ambra Stefani, Antelmi, Elena, Spiegelman, D, Ferman, Tanis J, Ross, Owen A, Alex Desautels, Gagnon, Jean-François, Boeve, Bradley F., Postuma, Ronald B, Dion, Patrick A., Tanis J. Ferman, Boivin, Michel, Fan, Dongsheng, Li, Jiao, Rouleau, Guy A., Young, Peter, J.W., Stefani, Ambra, Ruskey, JA, Ferini-Strambi, L, Dion, PA, Boeve, BF, Young, P, Bourassa, Cynthia V., Giuseppe Plazzi, Postuma, Ronald,, Fon, Edward, Ronald B. Postuma, Cynthia V. Bourassa, Dion, Patrick, Fon, Edward A., Rouleau, Guy A, Dupré, Nicolas, Stefani, A, Ferman, TJ, Fon, Edward A, Hu, Michele, Elena Antelmi, Fan, D, Edward A. Fon, Rouleau, Guy, Ross, Owen A., Spiegelman, Dan, Zhou, S, Claire S. Leblond, Jiao Li, Amirthagowri Ambalavanan, Heidbreder, Anna, Postuma, RB, Postuma, Ronald, B., Boeve, Bradley, Arnulf, I, Gan-Or, Ziv, Leblond, Claire, Charley Monaca, Christelle, Laurent, Sandra, Valérie Cochen De Cock, Jacques Y. Montplaisir, Ambalavanan, Amirthagowri, Labbe, Catherine, Bourassa, Cynthia, Leblond, Claire S, Jay P. Ross, Ruskey, Jennifer, Dion, Patrick A, Ross, Jay P., Desautels, Alex, Fon, EA, Isabelle Arnulf, Gan-Or, Z, Bradley F. Boeve, Leblond, Claire S., Laurent, SB, Dongsheng Fan, Montplaisir, Jacques Y., Owen A. Ross, Li, J, Cochen De Cock, V, Montplaisir, Jacques, Montplaisir, Jacques Y, Rouleau, GA, Ross, Jay P, Montplaisir, JY, Hu, Michele T. M., Ziv Gan-Or, Bourassa, CV, Michel Boivin, Young, Peter,, Ross, OA, Patrick A. Dion, Heidbreder, A, Hu, Michele T M, Boeve, Bradley F, Birgit Högl, Sandra B Laurent, Cochen De Cock, Valérie, Hu, Michele T.M., Leblond, CS, Plazzi, Giuseppe, Zhou, Sirui, Anna Heidbreder, Boivin, M, Guy A. Rouleau, Dauvilliers, Y, Arnulf, Isabelle, Jennifer A. Ruskey, Sirui Zhou, Catherine Labbe, Young P., Fon E. A., Montplaisir J. Y., Stefani A., Desautels A., Labbe C., Dauvilliers Y., Ambalavanan A., Leblond C. S., Boivin M., Ferini-Strambi L., Postuma R. B., Fan D., Charley Monaca C., Ferman T. J., Ross O. A., Ruskey J. A., Gan-Or Z., Cochen De Cock V., Ross J. P., Spiegelman D., Hogl B., Dion P. A., Plazzi G., Zhou S., Dupre N., Boeve B. F., Arnulf I., Laurent S. B., Li J., Hu M. T. M., Bourassa C. V., Rouleau G. A., Gagnon J. -F., Antelmi E., Heidbreder A. +174 morecore +1 more sourceH3K9me3 inhibition reverses Alzheimer's progression by restoring synaptic and immune proteostasis across the brain–retina axis
Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.Abstract INTRODUCTION
Epigenetic dysregulation is increasingly linked to aging and neurodegeneration, yet its contribution to retinal and brain pathology in Alzheimer's disease (AD) remains unclear. METHODS
We quantified the repressive epigenetic mark histone H3 lysine 9 trimethylation (H3K9me3) in post mortem retinas and brains from donors spanning ...Dieu‐Trang Fuchs, Jean‐Philippe Vit, Altan Rentsendorj, Yosef Koronyo, Julia Sheyn, Bhakta Prasad Gaire, Saba Shahin, Haoshen Shi, Oksana Chepurna, Miyah R. Davis, Jered W. Wilson, Stuart L. Graham, Vivek K. Gupta, Lon S. Schneider, Michael T. Kleinman, Tao Sun, Margaret Fahnestock, David A. Horne, Mehdi Mirzaei, Keith L. Black, Maya Koronyo‐Hamaoui +20 morewiley +1 more source
