Results 61 to 70 of about 7,681 (165)
Maraviroc/raltegravir simplification strategy following 6 months of quadruple therapy with tenofovir/emtricitabine/maraviroc/raltegravir in treatment-naive HIV patients
, 2016 International audienceOBJECTIVE: We assessed the virological efficacy of a 6 month maraviroc/raltegravir simplification strategy following 6 months of quadruple therapy combining tenofovir disoproxil fumarate/emtricitabine with maraviroc/raltegravir ...Lucht, Frédéric, Trabaud, Mary-Anne, Brochier, Corinne, Gagnieu, Marie-Claude, Jacomet, Christine, Cottalorda-Dufayard, Jacqueline, Vassallo, Matteo, Cotte, Laurent, Gatey, Caroline, Izopet, Jacques, Raffi, François, Durant, Jacques, Dellamonica, Pierre, Pradat, Pierre +13 morecore +1 more sourceChiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality, Volume 38, Issue 7, July 2026.Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu +1 morewiley +1 more sourceMaraviroc for previously treated patients with R5 HIV-1 infection
, 2008 Background CC chemokine receptor 5 antagonists are a new class of antiretroviral agents.Methods We conducted two double- blind, placebo- controlled, phase 3 studies - Maraviroc versus Optimized Therapy in Viremic Antiretroviral Treatment- Experienced ...Rafael E Campo, Jason Andrew Flamm, Anthony M Allworth, Shawn K Hassler, Robert Ray Redfield, Barbara H Wade, Bernard Hirschel, Robert H Keller, Steven Santiago, Paul Edward Sax, Anita R Rachlis, Brian Conway, David Wright, Gary Blick, Silver Sisneros, Amy Seinfeld, George Ghazaros Burnazian, Donna Elaine Sweet, Nicholas Doong, Bruce Stephen Rashbaum, Sullivan, John, Norman J Roth, Jacob Paul Lalezari, Leon Liang-Yu Lai, Stuart J Rosser, Roberto Claudio Arduino, Chiu-Bin Hsiao, Robert Charles Kalayjian, Francois Laplante, Giampiero Carosi, Michael Saag, Lalezari, Jacob, Goran Miljkovic, Enos Bernasconi, Barbara Romanowski, John Chuah, Fernando Aiuti, Jack Thomas Stapleton, van der Ryst, Elna, Cecile Tremblay, Allan Rowan Kelly, Richard Craig Reichman, Cristina Sarria, Julio S G Montaner, Schlomo Staszewski, Magnus Gisslen, David Holden Henry, Stefan Esser, Jan van Lunzen, Anne B Morris, Catherine Maria Creticos, Dieter Schuster, Gerald Pierone, Daniel S Berger, Roger P Leblanc, Jacques Reynes, Patrick G Clay, Robert Flisiak, Francois Raffi, Roy Steigbigel, Rodger David Macarthur, Gulick, Roy M, Andreas Trein, Margaret A Johnson, Mark Leslie Tanner, Jean-Francois Delfraissy, Peter Kadlecik, William James Towner, Paolo Emilio Manconi, Susan Swindells, Bisher Akil, Barbara Marie Gripshover, Corklin R Steinhart, Andrzej Horban, Steven M Fine, Jean Christophe Goffard, Clumeck, Nathan, Mark Oette, Horban, Andrzej, Lutwinus Weitner, William David Hardy, Kunthavi Sathasivam, Lawrence Edward Feldman, Jerome A Ernst, Sorana Segal-Maurer, Anna Boron-Kaczmarska, Santiago Moreno, Joseph P McGowan, Richard Harold Haubrich, Stockton Edward Roberts, Juan Julian Gonzalez Garcia, Jeffrey Eliot Galpin, Roy Gulick, Christophe Piketty, Harold Luther Martin, Leslie E Diaz, Laurent Cotte, Jose Norberto Hernandez, Gregory John Malanoski, Federico Pulido Ortega, Andreas Plettenberg, Alfred F Burnside, Cassy Workman, Karam Chucri Mounzer, Renaud Verdon, Norman Peter Markowitz, Jeffrey P Nadler, Emanuel Gallant, Jennifer Frances Hoy, Paula Rosa Greiger-Zanlungo, Edwin DeJesus, Edmund Wilkins, Javier Osvaldo Morales-Ramirez, Gregg Oscar Coodley, Stephen Eliot Follansbee, Tomasz Smiatacz, Jorge E Rodriguez, Jose Iribarren Loyarte, Robert P Smith, John Buscemi Montana, Zaher Shebib, Mayer, George L Drusano, Gary Green, Howard MOTIVATE Study Teams: Jonathan Angel, Antonius Mutz, Hans-Juergen Stellbrink, Felix Gutierrez, Thomas Harrer, Angela Xavier, Francesco Mazzotta, Marek Beniowski, Harry William Lampiris, Anthony LaMarca, Gilles Pialoux, Sky Robert Blue, Jesse Pullen Penico, Peter Jerome Ruane, Ralph Liporace, Henning Drechsler, Eliot Warren Godofsky, Roberto Esposito, Robert S Jones, Lynette H Posorske, William Jay Robbins, Marchina Elisabeth Van der Ende, Juan Gonzalez Lahoz, Jayashree Ravishankar, Dean Wilcox, Matthias Cavassini, Bernard C Vandercam, Milos Opravil, David Cooper, Barry Stephen Zingman, Rafael Rubio Garcia, Bienvenido Gamulo Yangco, Francesco Montella, Adriano Lazzarin, L W Preston Church, Sujata Lalla-Reddy, Paul Richard Skolnik, Kevin A Gough, Roberto B Corales, Wohlfeiler, Michael, Steven Miles, John D Brand, Danielle Rouleau, Roland Landman, Joseph G Timpone, Laura Kogelman, Lothar Schneider, Frances Wallach, Barbara J Hanna, Thomas B Campbell, Dominic Dwyer, Gerd Fätkenheuer, Trevor N Hawkins, David James Prelutsky, Richard G Lalonde, Frank-Detlef Goebel, Jorg-Andres Rump, Jonathan N Weber, Robert Owen Brenna, Donna Mildvan, Antonio Rivero, Michael Alan Horberg, Juergen Rockstroh, McHale, Mary, Antonio Di Biagio, James Michael Sosman, Heribert Knechten, Thomas Mc Donald File, Tomasz Mach, Patricia Dellot, James Riddell, Louis Marshall Sloan, Leonel Perez-Limonte, Jeffrey Lloyd Lennox, Johannes Richard Bogner, Jeffrey Howard Burack, J M Prins, Philippa Jane Easterbrook, Enzo Raise, David Asmuth, Fiona Smaill, Martin Wiselka, Barbara A Atkinson, David J White, Robert Anderson Myers, Christos Tsoukas, Alain Lafeuillade, Barry Michael Rodwick, Clemens Richter, Ilja Mohandas Hoepelman, Pierre-Marie Girard, Goodrich, James, Kathleen King Casey, Gladys E Sepulveda-Arzola, Markus Mueller, Nadler, Jeffrey, Matthew Leibowitz, Michele Bentata, Diana Antoniskis, Patrick William Daly, Karlsson, Anders, Nicholaos C Bellos, Dorece G Norris, Victoria Lee Sharp, Getachew Feleke, Robert Key Bolan, Michel Moutschen, Rosalinde Maria Perenboom, Winkler Weinberg, Melanie Ann Thompson, Bonaventura Clotet, Stephen Lawrence Becker, Clifford L Leen, Frances Fae Haas, Norbert H Brockmeyer, Alen Voskanian, Felstead, Steve, Clotet, Bonaventura, Stephen Lloyd Green, Ronald Takeshi Mitsuyasu, Alexander A McMeeking, Dunne, Michael W, Ricky K Hsu, Jacques Durant, Charles Byron Hicks, Philip Hay, Edmund Ong, Lawrence E Schwartz, Benoit Trottier, Stephen P Hauptman, Michael Grant Sension, Clifford A Kinder, Martin Fisher, James Sampson, William Keith Henry, Richard J Moore, Anders Karlsson, Pere Domingo Pedrol, George William Beatty, Laurent Hocqueloux, Isabelle Poizot Martin, Reinhold E Schmidt, Ana Maria Alvarez-Jacinto, Daniel Benjamin Klein, Sylvie Trottier, Dante Bassetti, Claudia Martorell, Peter Gordon, Jean-Michel Molina, Paul Peniston Cook, Shubha Kerkar, Sally Williams, Fernando Lozano de Leon, Stephen David Shafran, Mark R Nelson, Daniel Edward Nixon, Pablo Tebas, Joseph G Jemsek, Judith E Feinberg, Carmen D Zorrilla, DeJesus, Edwin, Richard K Groger, Lucia M Martinez-Bejar, Nathan Clumeck, Michael Bruce Wohlfeiler, Pietro Vernazza, Peter Kern, Ridgway, Caroline, Julian Gold, Patrick L McLeroth, Paul Joseph Cimoch, Daniel Pearce, Keikawus Arasteh, Neil J Bodsworth, David Allen Wheeler, Montana, John B, Steven Williams, Christine Zurawski, Jason Mark Leider, Janak Koirala, Ethan Rubinstein, Waldemar Halota, Todd Stephen Wills, Mark T Bloch, Sharon Lynn Walmsley, Manuel Battegay, Francesco Leoncini, Todd Allen Fralich, Pietro Caramello, Pompeyo Viciana Fernandez, Calvin J Cohen, Dirk Vogelaers, Vicenzo Vullo, Jose Josep Gatell Artigas, Leo Flamholc +318 morecore +2 more sourcesPreclinical systematic review of CCR5 antagonists as cerebroprotective and stroke recovery enhancing agents
eLifeC-C chemokine receptor type 5 (CCR5) antagonists may improve both acute stroke outcome and long-term recovery. Despite their evaluation in ongoing clinical trials, gaps remain in the evidence supporting their use.Ayni Sharif, Matthew S Jeffers, Dean A Fergusson, Raj Bapuji, Stuart G Nicholls, John Humphrey, Warren Johnston, Ed Mitchell, Mary-Ann Speirs, Laura Stronghill, Michele Vuckovic, Susan Wulf, Risa Shorr, Dar Dowlatshahi, Dale Corbett, Manoj M Lalu +15 moredoaj +1 more sourceT‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection
American Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.ABSTRACT
Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...Barbara L. Shacklett, Ramatoulaye H. Ouattara, April L. Ferre +2 morewiley +1 more sourceMarked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxis
Malaria Journal, 2011 The case of a 32-year-old Caucasian female with multi-drug resistant HIV-1 subtype B infection treated with a salvage regimen including maraviroc, raltegravir, etravirine and unboosted saquinavir who started atovaquone/proguanil prophylaxis, is reported. Ivanovic Jelena, Gallo Anna L, D'Avolio Antonio, Tempestilli Massimo, Bellagamba Rita, Tommasi Chiara, Nicastri Emanuele, Pucillo Leopoldo P, Narciso Pasquale +8 moredoaj +1 more source
