Results 101 to 110 of about 1,701,603 (284)
Forty-Five Years of Marburg Virus Research
Viruses, 2012 In 1967, the first reported filovirus hemorrhagic fever outbreak took place in Germany and the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg virus, is one of the most deadly human pathogens.
Kristina Brauburger +3 more
doaj +1 more source
Organoid Models to Study Human Infectious Diseases
Cell Proliferation, EarlyView.Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu +4 more
wiley +1 more source
Ebola et Marburg : les hommes contre-attaquent [PDF]
, 2006 La fréquence des épidémies de fièvres hémorragiques à virus Ebola ou Marburg constatée en Afrique Centrale est en augmentation depuis une dizaine d’années.
Alazard-Dany, Nathalie +2 more
core
Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis [PDF]
, 2017 Ebola virus (EBOV) is an enveloped negative-sense RNA virus that causes sporadic outbreaks with high case fatality rates. Ebola viral protein 30 (eVP30) plays a critical role in EBOV transcription initiation at the nucleoprotein (eNP) gene, with ...
Amarasinghe, Gaya K +6 more
core +2 more sources
Mining of Marburg Virus Proteome for Designing an Epitope-Based Vaccine
Frontiers in Immunology, 2022 Marburg virus (MARV) is one of the most harmful zoonotic viruses with deadly effects on both humans and nonhuman primates. Because of its severe outbreaks with a high rate of fatality, the world health organization put it as a risk group 4 pathogen and ...
M. Soltan +12 more
semanticscholar +1 more source
Diagnostic electron microscopy in human infectious diseases – Methods and applications
Journal of Microscopy, EarlyView.Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley +1 more source
VP24-Karyopherin alpha binding affinities differ between Ebolavirus species, nfluencing interferon inhibition and VP24 stability [PDF]
, 2017 Zaire ebolavirus (EBOV), Bundibugyo ebolavirus (BDBV), and Reston ebolavirus (RESTV) belong to the same genus but exhibit different virulence properties.
Alinger, Joshua B +6 more
core +2 more sources
Carbohydrate structure of Marburg virus glycoprotein [PDF]
Glycobiology, 1992 Marburg virus was propagated in E6 cells, a cloned cell line of Vero cells, in the presence of [6-3H]glucosamine. Radiolabelled viral glycoprotein was digested with trypsin, and oligosaccharides were liberated by sequential treatment with endo-beta-N-acetylglucosaminidase H, peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase F and O-glycosidase,
Heinz Feldmann +4 more
openaire +2 more sources
Medical and Veterinary Entomology, EarlyView.The principal arboviral vector Aedes aegypti can develop in coastal brackish water field habitats (0.5–15 g/L salt) with larvae possessing thicker cuticles and greater resistance to the larvicide Temephos. Females emerging from brackish water‐developing preimaginal stages are now shown to have thicker and remodelled leg and abdominal cuticles and ...
Kokila Sivabalakrishnan +6 more
wiley +1 more source
Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization. [PDF]
, 2017 BACKGROUND: The recent West African Ebola epidemic led to accelerated efforts to test Ebola vaccine candidates. As part of the World Health Organisation-led VSV Ebola Consortium (VEBCON), we performed a phase I clinical trial investigating rVSV-ZEBOV (a ...
Addo, MM +22 more
core +1 more source