Results 41 to 50 of about 36,270 (266)

VP24-Karyopherin alpha binding affinities differ between Ebolavirus species, nfluencing interferon inhibition and VP24 stability [PDF]

open access: yes, 2017
Zaire ebolavirus (EBOV), Bundibugyo ebolavirus (BDBV), and Reston ebolavirus (RESTV) belong to the same genus but exhibit different virulence properties.
Alinger, Joshua B   +6 more
core   +2 more sources

Structural insights into the mechanism of archaellar rotational switching

open access: yesNature Communications, 2022
Signal transduction via phosphorylated CheY is conserved in bacteria and archaea. In this study, the authors employ structural biochemistry combined with cell biology to delineate the mechanism of CheY recognition by the adaptor protein CheF.
Florian Altegoer   +10 more
doaj   +1 more source

Marburg virus disease: A summary for clinicians

open access: yesInternational Journal of Infectious Diseases, 2020
Objectives: This article summarizes the countermeasures for Marburg virus disease, focusing on pathogenesis, clinical features and diagnostics. There is an emphasis on therapies and vaccines that have demonstrated, through their evaluation in nonhuman ...
Mark G. Kortepeter   +3 more
doaj   +1 more source

A review of treating viral outbreaks with self-assembled nanomaterial-like peptides: From Ebola to the Marburg virus

open access: yesOpenNano, 2022
Cases of the Marburg virus have started to rise and there is an urgent need to find a cure or therapy before another world-wide quarantine is introduced.
Alaa F. Nahhas, Thomas J. Webster
doaj   +1 more source

Rapid bedside inactivation of Ebola virus for safe nucleic acid tests [PDF]

open access: yes, 2016
Rapid bedside inactivation of Ebola virus would be a solution for the safety of medical and technical staff, risk containment, sample transport and high-throughput or rapid diagnostic testing during an outbreak.
Bragstad, Karoline   +9 more
core   +2 more sources

Marburg virus: an emerging global threat

open access: yesJournal of Zoonotic Diseases
Marburg virus disease is a rare, but severe illness caused by highly pathogenic Marburg virus, a member of the Filoviridae family. The virus was first identified in 1967 in Marburg and Frankfurt, Germany, as well as Belgrade, Serbia.
Balamurugan Shanmugaraj
doaj   +1 more source

Ebola and Marburg virus vaccines [PDF]

open access: yesVirus Genes, 2017
The filoviruses, Ebola virus (EBOV), and Marburg virus (MARV), are among the most pathogenic viruses known to man and the causative agents of viral hemorrhagic fever outbreaks in Africa with case fatality rates of up to 90%. Nearly 30,000 infections were observed in the latest EBOV epidemic in West Africa; previous outbreaks were much smaller ...
Reynolds, Pierce, Marzi, Andrea
openaire   +2 more sources

Data from: A systematic review and meta-analysis of seroprevalence surveys of ebolavirus infection [PDF]

open access: yes, 2017
The dataset contains findings and information from 51 seroprevelance studies performed from on samples collected from 1961 to 2016. These investigated 84 exposure-defined subgroups of subjects reported to have had no symptoms of EVD during the outbreak ...
Bower, Hilary, Glynn, Judith
core   +2 more sources

Forty Years of Marburg Virus [PDF]

open access: yesThe Journal of Infectious Diseases, 2007
Forty years ago, in early August 1967, the first filovirus ever detected, Marburg virus, made its appearance in Europe, causing severe and often fatal hemorrhagic fever in laboratory workers in Marburg and Frankfurt and, about 4 weeks later, in Belgrade. The etiological agent was isolated and identified by the combined efforts of virologists in Marburg
Werner, Slenczka, Hans Dieter, Klenk
openaire   +2 more sources

Wave-like spread of Ebola Zaire [PDF]

open access: yes, 2005
In the past decade the Zaire strain of Ebola virus (ZEBOV) has emerged repeatedly into human populations in central Africa and caused massive die-offs of gorillas and chimpanzees.
Leslie A Real   +3 more
core   +5 more sources

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