Results 21 to 30 of about 4,442 (181)

Characterization of Ravn virus viral shedding dynamics in experimentally infected Egyptian rousette bats (Rousettus aegypticus) [PDF]

Journal of Virology
Marburg virus (MARV) and Ravn virus (RAVV), the only two known members of the species Orthomarburgvirus marburgense (family Filoviridae), are causative agents of Marburg virus disease, a severe viral disease that typically emerges in sub-Saharan Africa ...
Jessica A. Elbert, Amy J. Schuh, Brian R. Amman, Jonathan C. Guito, James C. Graziano, Tara K. Sealy, Elizabeth W. Howerth, Jonathan S. Towner   +7 more
doaj   +2 more sources

Can Marburg virus be sexually transmitted?

Health Science Reports
Background and Aim Marburg virus (MARV) is a highly virulent virus of animal origin and the cause of a lethal infection (known as Marburg virus disease [MVD]) with a case‐fatality ratio ranging from 24% to 90%.
Hassan Karami, Arash Letafati, Somayeh Sadat Hosseini Fakhr   +2 more
doaj   +2 more sources

Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health. [PDF]

Microb Biotechnol
Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Brüssow H.
europepmc   +2 more sources

Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using <i>Drosophila</i> S2 Cells. [PDF]

Eng Life Sci
ABSTRACT Marburg marburgvirus (MARV) is a highly virulent human pathogen with limited therapeutic options. Recombinant MARV glycoprotein (GP) produced in Drosophila Schneider 2 (S2) cells has been extensively investigated as potential vaccine antigen with promising efficacy demonstrated in nonhuman primate models.
Göbel S, Mayerlen L, Eiser IY, Fichtmueller L, Clements D, Reichl U, Genzel Y, Lehrer A.   +7 more
europepmc   +2 more sources

Marburg virus survivor immune responses are Th1 skewed with limited neutralizing antibody responses. [PDF]

, 2017
Until recently, immune responses in filovirus survivors remained poorly understood. Early studies revealed IgM and IgG responses to infection with various filoviruses, but recent outbreaks have greatly expanded our understanding of filovirus immune ...
Cose, S, Dahan, CVA, Dye, JM, Egesa, M, Habibulin, P, Herbert, AS, James, RM, Kuehne, AI, Lobel, L, Lutwama, JJ, Sobarzo, A, Stonier, SW   +11 more
core   +4 more sources

Marburg virus outbreak in Tanzania: A threat to global health security

Public Health Challenges, Volume 2, Issue 4, December 2023., 2023
Abstract The current Marburg virus (MARV) outbreak in Tanzania served as a stark reminder of the ongoing threat posed by emerging infectious diseases and the urgent need for global health security. The Tanzanian Ministry of Health (MoH) officially declared the outbreak on March 21, 2023.
Majani Edward, Godfred Yawson Scott, Withness John, Martha Ernest Rajabu, Elton Mahulu, Shuaibu Saidu Musa, Lucero‐Prisno III Don Eliseo   +6 more
wiley   +1 more source

The neglected continuously emerging Marburg virus disease in Africa: A global public health threat

Health Science Reports, Volume 6, Issue 11, November 2023., 2023
Abstract Background and Aim Severe viral hemorrhagic fever (VHF) is caused by Marburg virus which is a member of the Filoviridae (filovirus) family. Many Marburg virus disease (MVD) outbreaks are reported in five decades. A major notable outbreak with substantial reported cases of infections and deaths was in 2022 in Uganda.
Devang Srivastava, Lakshmi Venkata Simhachalam Kutikuppala, Pooja Shanker, Rudra Narayan Sahoo, Gurudutta Pattnaik, Rasmita Dash, Venkataramana Kandi, Azaj Ansari, Snehasish Mishra, Dhruv N. Desai, Ranjan K. Mohapatra, Ali A. Rabaan, Md. Kudrat‐E‐Zahan   +12 more
wiley   +1 more source

The mortality, modes of infection, diagnostic tests, and treatments of Marburg virus disease: A systematic review

Health Science Reports, Volume 6, Issue 9, September 2023., 2023
Abstract Background and Aims Marburg virus (MARV) has regularly affected people since 1967 causing multiple outbreaks. There are presently no authorized therapies for the fatal Marburg virus disease (MVD), which poses an imminent risk to global public health.
Deekshitha Alla, Sai Sri Hari Paruchuri, Angad Tiwari, Sai Santhosha Mrudula Alla, Rakesh Thulaseedharan Pillai, Sandeep Kumar Reddy Bandakadi, Anju Pradeep, Dhruv Jayeshkumar Shah, Mert Sabıroğlu, Sachi Chavda, Patrick Biziyaremye   +10 more
wiley   +1 more source

Investigation of the Lipid Binding Properties of the Marburg Virus Matrix Protein VP40 [PDF]

, 2015
Marburg virus (MARV), which belongs to the virus family Filoviridae, causes hemorrhagic fever in humans and nonhuman primates that is often fatal. MARV is a lipid-enveloped virus that during the replication process extracts its lipid coat from the plasma
Stahelin, Robert V., Wijesinghe, Kaveesha J.   +1 more
core   +1 more source

Ebola outbreak in DRC and Uganda; an East African public health concern

Health Science Reports, Volume 6, Issue 8, August 2023., 2023
Abstract On August 21, 2022, healthcare authorities in the Democratic Republic of the Congo (DRC) announced an outbreak of Ebola virus disease in North Kivu Province, bringing the total to 15 outbreaks nationwide. On September 20, 2022, Uganda's authorities declared an outbreak of the Sudan strain of the Ebola virus following a confirmed a case in ...
Sospeter Berling Sospeter, Okereke Promise Udohchukwu, Juvenali Ruaichi, Goodluck Nchasi, Innocent Kitandu Paul, Andrew Marvin Kanyike, Rebecca Susan Dewey   +6 more
wiley   +1 more source