Results 161 to 170 of about 2,647 (192)

Evaluation of location tracking methods to understand human-wildlife contact and pathogen spillover risks

open access: yes
Lim RN   +15 more
europepmc   +1 more source

Ebolavirus and Marburgvirus: Insight the Filoviridae family [PDF]

open access: yesMolecular Aspects of Medicine, 2008
Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins. No significant homology is observed between filovirus proteins and any known macromolecule.
Maria Rosaria Capobianchi   +2 more
exaly   +9 more sources

Budding of Marburgvirus is associated with filopodia [PDF]

open access: yesCellular Microbiology, 2007
Viruses exploit the cytoskeleton of host cells to transport their components and spread to neighbouring cells. Here we show that the actin cytoskeleton is involved in the release of Marburgvirus (MARV) particles. We found that peripherally located nucleocapsids and envelope precursors of MARV are located either at the tip or at the side of filopodial ...
Stephan Becker, Richard E Cheney
exaly   +3 more sources
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Immunoinformatic screening of Marburgvirus epitopes and computational investigations of epitope-allele complexes

International Immunopharmacology, 2022
Marburgvirus (MARV), a member of the Filovirus family, causes severe hemorrhagic fever in humans. Currently, there are no approved vaccines or post exposure treatment methods available against MARV. With the aim of identifying vaccine candidates against MARV, we employ different sequence-based computational methods to predict the MHC-I and MHC-II T ...
Elumalai Pavadai   +2 more
exaly   +3 more sources

Pseudotyped Viruses for Marburgvirus and Ebolavirus

2023
Marburg virus (MARV) and Ebola virus (EBOV) of the Filoviridae family are the most lethal viruses in terms of mortality rate. However, the development of antiviral treatment is hampered by the requirement for biosafety level-4 (BSL-4) containment. The establishment of BSL-2 pseudotyped viruses can provide important tools for the study of filoviruses ...
Li, Zhang, Shou, Liu, Youchun, Wang
openaire   +2 more sources

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