Pathology and Molecular Diagnosis of Marek’s Disease Virus in Chickens in Nigeria [PDF]
ScientificaMarek’s disease caused by Marek’s disease virus (MDV) serotype 1 is an economically important neoplastic disease of poultry. Diagnosis of this disease is usually based on clinical signs, postmortem lesions, and diagnostic tests like cytology ...
Olusegun Adesina Fagbohun +11 more
doaj +2 more sources
Integrated analysis of methylation profiles and transcriptome of Marek's disease virus-infected chicken spleens reveal hypomethylation of CD4 and HMGB1 genes might promote Marek's disease tumorigenesis [PDF]
Poultry Science, 2023 : Marek's disease (MD) is a lymphoproliferative neoplastic disease caused by Marek's disease virus (MDV). Previous studies have showed that DNA methylation was involved in MD development, but systematic studies are still lacking.
Yiming Yuan +11 more
doaj +2 more sources
Amino acid insertion in the Meq protein of Marek’s disease virus, an avian oncogenic herpesvirus, accelerates tumorigenesis [PDF]
Microbiology SpectrumMarek’s disease virus (MDV) causes lymphomas (Marek’s disease) in chickens. Despite vaccination, MDV field strains exhibit increased virulence, and sporadic outbreaks are still reported.
Jumpei Sato +9 more
doaj +2 more sources
Application of lentinan in suppression of Marek's disease virus infection [PDF]
Poultry ScienceMarek's disease virus (MDV) is an extremely widespread avian immunosuppressive virus. In recent years, many reports have shown that there are still cases of MDV infection and immunosuppression after immunization with the vaccine. Consequently, there is a
Qiming Gao +6 more
doaj +2 more sources
Temperature-induced reactivation of Marek's disease virus-transformed T cells ex vivo [PDF]
Frontiers in Veterinary Science, 2023 Marek's disease virus (MDV) establishes latency in chicken T lymphocytes that can lead to T cell transformation and cancer. Transformed Marek's disease chicken cell lines (MDCCs) can be expanded ex vivo and provide a valuable model to study latency ...
Yung-Tien Tien +2 more
doaj +2 more sources
Viral miRNA delivered by exosomes from Marek's disease virus-transformed lymphoma cell line exerts regulatory function in internalized primary chicken embryo fibroblast cells [PDF]
Tumour Virus ResearchIn the past decade, research has demonstrated that viral miRNAs encoded by a number of viral genomes, particularly by most of the herpesvirus including Marek's disease virus (MDV), play important regulatory roles in viral infection, replication, and ...
Man Teng +6 more
doaj +2 more sources
Occurrence of Marek's disease in vaccinated Algerian broiler breeder flocks: A histopathological survey [PDF]
Veterinary World, 2021 Background and Aim: Marek's disease (MD) is a lymphoproliferative disease that occurs in chickens. In the absence of control measures, MD causes devastating losses to commercial poultry flocks.
Abdelaziz Lounas +3 more
doaj +1 more source
Analysis of DNA methylation of CD79B in MDV-infected chicken spleen
Journal of Integrative Agriculture, 2021 Marek's disease (MD), an immunosuppressive disease induced by Marek's disease virus (MDV), provides an ideal model for studying diseases caused by a carcinogenic virus. CD79B is a B-cell antigen receptor complex-associated protein β-chain precursor which
Lu-lu WANG +4 more
doaj +1 more source
Outbreak of Marek’s Disease in Chicken Flocks with Uncommon Pattern of Gross Lesions [PDF]
Journal of Veterinary and Animal Sciences, 2023 Marek’s disease is one of the highly contagious and oncogenic diseases of poultry that remains as a threat to the fast-growing poultry sector, even after proper vaccination.
R. Geethanjali +4 more
doaj +1 more source
Animals, 2022 Marek’s disease is an infectious disease in poultry that usually appears in neural and visceral tumors. This disease is caused by Gallid alphaherpesvirus 2 infection in lymphocytes, and its meq gene is commonly used in virulent studies for coding the key
Baolin Song +9 more
doaj +1 more source