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The immune cell landscape and response of Marek’s disease resistant and susceptible chickens infected with Marek’s disease virus [PDF]
Scientific Reports, 2023 Genetically resistant or susceptible chickens to Marek’s disease (MD) have been widely used models to identify the molecular determinants of these phenotypes.
Wesley C. Warren +8 more
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Animals, 2022 Marek’s disease is an infectious disease in poultry that usually appears in neural and visceral tumors. This disease is caused by Gallid alphaherpesvirus 2 infection in lymphocytes, and its meq gene is commonly used in virulent studies for coding the key
Baolin Song +9 more
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PLoS Biology, 2021 Viral diseases pose major threats to humans and other animals, including the billions of chickens that are an important food source as well as a public health concern due to zoonotic pathogens.
Samer Halabi +9 more
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Pathology and Molecular Diagnosis of Marek’s Disease Virus in Chickens in Nigeria [PDF]
ScientificaMarek’s disease caused by Marek’s disease virus (MDV) serotype 1 is an economically important neoplastic disease of poultry. Diagnosis of this disease is usually based on clinical signs, postmortem lesions, and diagnostic tests like cytology ...
Olusegun Adesina Fagbohun +11 more
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Frontiers in Immunology, 2022 Marek’s disease virus (MDV), the etiologic agent for Marek’s disease (MD), causes a deadly lymphoproliferative disease in chickens. Causes of the well-documented association between genetically defined lines of chicken and resistance to MD remain unknown.
Nitish Boodhoo +2 more
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Amino acid insertion in the Meq protein of Marek’s disease virus, an avian oncogenic herpesvirus, accelerates tumorigenesis [PDF]
Microbiology SpectrumMarek’s disease virus (MDV) causes lymphomas (Marek’s disease) in chickens. Despite vaccination, MDV field strains exhibit increased virulence, and sporadic outbreaks are still reported.
Jumpei Sato +9 more
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Animals, 2020 Marek’s disease is widely controlled by vaccination programs; however, chickens are not totally protected, especially immediately after the vaccination when a strong challenge could interfere with the effectiveness of vaccination in the absence of proper
Alessandro Stamilla +8 more
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Integrated analysis of methylation profiles and transcriptome of Marek's disease virus-infected chicken spleens reveal hypomethylation of CD4 and HMGB1 genes might promote Marek's disease tumorigenesis [PDF]
Poultry Science, 2023 : Marek's disease (MD) is a lymphoproliferative neoplastic disease caused by Marek's disease virus (MDV). Previous studies have showed that DNA methylation was involved in MD development, but systematic studies are still lacking.
Yiming Yuan +11 more
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Marek's disease herpesvirus serotype 1 in broiler breeder and layer chickens in Malaysia [PDF]
Veterinary World, 2019 Aim: This study aimed to investigate the occurrence of Marek's disease (MD) in five poultry farms in Malaysia using postmortem examination, histopathology, and polymerase chain reaction (PCR).
Iryanti Othman, Erkihun Aklilu
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Application of lentinan in suppression of Marek's disease virus infection [PDF]
Poultry ScienceMarek's disease virus (MDV) is an extremely widespread avian immunosuppressive virus. In recent years, many reports have shown that there are still cases of MDV infection and immunosuppression after immunization with the vaccine. Consequently, there is a
Qiming Gao +6 more
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