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Marek's Disease Virus Morphogenesis
Avian Diseases, 2013Marek's disease virus (MDV) is a highly contagious virus that induces T-lymphoma in chicken. This viral infection still circulates in poultry flocks despite the use of vaccines. With the emergence of new virulent strains in the field over time, MDV remains a serious threat to the poultry industry.
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Genomics and Marek’s disease virus
Cytogenetic and Genome Research, 2007Marek’s disease virus (MDV), a lymphotrophic alphaherpesvirus of chickens, causes a disease that is characterized by tumor formation, immunosuppression and neurological disorders. Recent developments in chicken genomics have been applied to studies of MDV and have advanced our understanding of both the virus and the disease it causes.
J, Burnside, R W, Morgan
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1985
Publisher Summary Marek's disease (MD)—a malignant lymphomatosis in chickens—is caused by Marek's disease virus (MDV) of the family Herpesviridae. This chapter reviews recent advances in MD research, especially in the field of molecular biology. Various antigens present in MDV virions, MDV-infected cells, or MD lymphoma cells have been suspected as ...
S, Kato, K, Hirai
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Publisher Summary Marek's disease (MD)—a malignant lymphomatosis in chickens—is caused by Marek's disease virus (MDV) of the family Herpesviridae. This chapter reviews recent advances in MD research, especially in the field of molecular biology. Various antigens present in MDV virions, MDV-infected cells, or MD lymphoma cells have been suspected as ...
S, Kato, K, Hirai
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2001
MDV latency is defined as the persistence of the viral genome in the absence of production of infectious virus except during reactivation. A number of systems for studying MDV latency exist, and most involve the use of lymphoblastoid cells or tumors. It has been difficult to divorce latency and transformation.
R W, Morgan +6 more
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MDV latency is defined as the persistence of the viral genome in the absence of production of infectious virus except during reactivation. A number of systems for studying MDV latency exist, and most involve the use of lymphoblastoid cells or tumors. It has been difficult to divorce latency and transformation.
R W, Morgan +6 more
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Immune responses against Marek's disease virus
Animal Health Research Reviews, 2010AbstractIt is more than a century since Marek's disease (MD) was first reported in chickens and since then there have been concerted efforts to better understand this disease, its causative agent and various approaches for control of this disease. Recently, there have been several outbreaks of the disease in various regions, due to the evolving nature ...
Payvand, Parvizi +5 more
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Structural proteins of Marek's disease virus
Virology, 1972Abstract Marek's disease virus (MDV) was propagated in roller-bottle cultures of duck embryo fibroblasts and partially purified by sucrose gradient centrifugation. Analysis of viral protein by polyacrylamide gel electrophoresis revealed that at least eight proteins (designated VPI-VPVIII) were present in MDV. The VPI is the major viral protein.
J H, Chen +3 more
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International Journal of Cancer, 1975
AbstractImmunity against Marek's disease was conferred by the use of non‐infectious materials extracted with non‐ionic detergents from cells infected with the attenuated strain of Marek's disease virus (MDV). Antibody‐free Rhode Island Red chicks were inoculated at 1 week of age with cell extracts emulsified in Freund's complete adjuvant and were given
F, Lesnik, L J, Ross
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AbstractImmunity against Marek's disease was conferred by the use of non‐infectious materials extracted with non‐ionic detergents from cells infected with the attenuated strain of Marek's disease virus (MDV). Antibody‐free Rhode Island Red chicks were inoculated at 1 week of age with cell extracts emulsified in Freund's complete adjuvant and were given
F, Lesnik, L J, Ross
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Marek's Disease Virus in Commercial Turkey Flocks, Iran
Avian Diseases, 2023Marek's disease is a significant illness in chickens and a potential threat to the poultry industry worldwide. Marek's disease virus (MDV) causes immunosuppression and lymphoproliferative disease in chickens, but the turkey is an unusual host for the virus, and tumors caused by MDV in turkeys are unique.
Hossein, Hosseini +5 more
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Marek's disease virus: from miasma to model
Nature Reviews Microbiology, 2006Marek's disease virus (MDV) is an oncogenic herpesvirus that causes various clinical syndromes in its natural host, the chicken. MDV has long been of interest as a model organism, particularly with respect to the pathogenesis and immune control of virus-induced lymphoma in an easily accessible small-animal system.
Osterrieder, Nikolaus +4 more
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A study of vaccination against Marek's disease with an attenuated Marek's disease virus
Avian Pathology, 1974Approximately 2,000 day-old white leghorn chickens were distributed into 10 pens and half the pens vaccinated with the attenuated strain of HPRS-16. At 72 weeks of age, mortality from non-specific death and Marek's disease was 17.6% and 15.6% respectively, in vaccinated chickens compared with 14.2% and 51.7% in unvaccinated chickens.
C A, Jackson +4 more
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