Results 131 to 140 of about 2,649 (156)
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Veterinary Record, 1975
In field trials involving over 224,000 fowls in 11 different commercial flocks, three vaccines were used, namely a freeze-dried vaccine prepared from a turkey herpes virus, a cell-associated virus vaccine prepared from the same isolate and a cell-associated vaccine prepared from a strain of Marek's disease virus isolated from a fowl. The mortality from
J D, Blaxland, A J, Macleod, T, Hall
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In field trials involving over 224,000 fowls in 11 different commercial flocks, three vaccines were used, namely a freeze-dried vaccine prepared from a turkey herpes virus, a cell-associated virus vaccine prepared from the same isolate and a cell-associated vaccine prepared from a strain of Marek's disease virus isolated from a fowl. The mortality from
J D, Blaxland, A J, Macleod, T, Hall
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Isolation of Marek's disease virus: revisited
Avian Pathology, 2005Splenocytes from chickens infected with low-passage stocks of Marek's disease virus (MDV) RB-1B, a very virulent (vv) strain and vv+ RK-1 were used to compare the efficacy of chick kidney cells (CKC), chicken embryo fibroblasts (CEF) and chicken embryo kidney cells (CEKC) for virus isolation. CKC were superior to CEF and CEKC.
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The Genomic Structure of Marek’s Disease Virus
2001All herpesviruses contain linear, double-stranded DNA genome surrounded by a 100-nm diameter icosahedral protein capsid core consisting of 162 capsomers. In thin-section electron micrographs, an electron transparent region, termed the tegument, surrounds the capsid, which in turn is surrounded by a lipid-containing envelope.
R F, Silva, L F, Lee, G F, Kutish
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Immune Responses to Marek’s Disease Virus Infection
2001Marek’s disease (MD), a herpesvirus-induced lymphomatous disease in chickens, has attracted the interest of immunologists since MD virus (MDV) was isolated in 1968 and vaccines became available shortly afterwards (Witter 1985,Witter 2000). The pathogenesis of MD has been reviewed extensively (Calnek 1986,Calnek 1998,Calnek 2000; Schat 1987b). Infection
K A, Schat, C J, Markowski-Grimsrud
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Pathogenesis of Marek’s Disease Virus Infection
2001The term pathogenesis is most simply defined as the development of disease. Many uncomplicated infectious diseases proceed in a direct fashion from infection to a specific pathologic expression. However, other diseases are relatively complex in terms of pathogenesis; Marek’s disease (MD) most certainly belongs in this category.
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T-cell transformation by Marek's disease virus
Trends in Microbiology, 1999Marek's disease virus (MDV) is an avian herpesvirus that causes rapid development of T-cell lymphomas in chickens. The MDV genes currently thought to be involved in lymphomagenesis include a bZIP transactivator that is homologous to fos and jun oncogenes but do not appear to have counterparts in other oncogenic herpesviruses.
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Marek's Disease Virus-Induced Transient Cecal Tonsil Atrophy
Avian Diseases, 2014Marek's disease (MD) is a lymphoproliferative disease of domestic chickens that is caused by a highly cell-associated oncogenic alpha-herpesvirus, Marek's disease virus (MDV). MDV replicates in chicken lymphocytes and establishes a latent infection within CD4+ T cells. MD is characterized by bursal and thymic atrophy and rapid onset of T cell lymphomas
Mohammad, Heidari +2 more
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Effect of Phosphonoacetate on Marek's Disease Virus Replication
JNCI: Journal of the National Cancer Institute, 1976Phosphonoacetate (PA), but not any of its analogues tested, effectively inhibited avian herpesvirus replication and viral DNA synthesis in cell cultures. At 100 mug/ml culture medium, PA completely inhibited the replication of Marek's disease virus (MDV), herpesvirus of turkeys, and owl herpesvirus, but had no measurable effect on normal cell growth ...
L F, Lee +4 more
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Polyvalent Recombinant Marek’s Disease Virus Vaccine Against Poultry Diseases
2001In 1982, Mackett et al. (1982) and Panicali and Paoletti (1982) constructed a recombinant vaccinia virus expressing a foreign gene, the thymidine kinase (TK) gene of herpes simplex virus (HSV), which was inserted into the nonessential regions of the virus genome by homologous recombination.
K, Hirai, M, Sakaguchi
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Partial restriction map of Marek's disease virus DNA
Gene, 1982A partial restriction map of Marek's disease virus (MDV) DNA was constructed by digestion with endonucleases BamHI, Bg/I and SmaI and by blotting hybridization. The data suggest that there is a terminal heterogeneous sequence at least on one end of the MDV DNA molecule.
Y S, Lee, A, Tanaka, M, Nonoyama
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