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Latest Insights into Marek’s Disease Virus Pathogenesis and Tumorigenesis

Cancers, 2020
Marek’s disease virus (MDV) infects chickens and causes one of the most frequent cancers in animals. Over 100 years of research on this oncogenic alphaherpesvirus has led to a profound understanding of virus-induced tumor development.
L. D. Bertzbach, Andelé M. Conradie, Yu-qin You, B. Kaufer   +3 more
semanticscholar   +1 more source

Occurrence of Marek’s disease in Poland on the basis of diagnostic examination in 2015–2018

Journal of Veterinary Research, 2020
Marek’s disease (MD) is a tumourous disease caused by Marek’s disease virus (MDV) and most commonly described in poultry. The aim of the study was to determine the occurrence of Marek’s disease virus infections in Poland and analyse clinical cases in the
Kozdruń Wojciech, Styś-Fijoł Natalia, Czekaj Hanna, Piekarska Karolina, Niczyporuk Jowita Samanta, Stolarek Agnieszka   +5 more
doaj   +1 more source

Marek’s disease in the holland white crested chickens [PDF]

Veterinarski Glasnik, 2016
Marek’s disease is a viral lymphoproliferative disease of poultry characterized by the creation of lymphoma in muscle, skin, eye or internal organs.
Spalević Ljiljana, Maslić-Strižak Danka, Kureljušić Branislav, Milićević Vesna, Radanović Oliver, Jezdimirović Nemanja   +5 more
doaj   +1 more source

B cells do not play a role in vaccine-mediated immunity against Marek’s disease

Vaccine: X, 2022
Background: Marek’s disease virus (MDV), a highly oncogenic α-herpesvirus, is the etiological agent of Marek’s disease (MD) in chickens. The antiviral activity of vaccine-induced immunity against MD reduces the level of early cytolytic infection ...
Mohammad Heidari, Huanmin Zhang, Cari Hearn, Lakshmi Sunkara   +3 more
doaj   +1 more source

Morphological and Immunohistochemical Examination of Lymphoproliferative Lesions Caused by Marek’s Disease Virus in Breeder Chickens

Animals, 2020
Marek’s disease is widely controlled by vaccination programs; however, chickens are not totally protected, especially immediately after the vaccination when a strong challenge could interfere with the effectiveness of vaccination in the absence of proper
Alessandro Stamilla, Antonino Messina, Lucia Condorelli, Francesca Licitra, Francesco Antoci, Massimiliano Lanza, Guido Ruggero Loria, Giuseppe Cascone, Roberto Puleio   +8 more
doaj   +1 more source

IFNα and IFNγ Impede Marek’s Disease Progression [PDF]

, 2019
Marek’s disease virus (MDV) is an alphaherpesvirus that causes Marek’s disease, a malignant lymphoproliferative disease of domestic chickens. While MDV vaccines protect animals from clinical disease, they do not provide sterilizing immunity and allow ...
Bertzbach, Luca D., Fehler, Frank, Harlin, Olof, Härtle, Sonja, Kaspers, Bernd, Kaufer, Benedikt B., Vychodil, Tereza   +6 more
core   +1 more source

The Meq Gene Molecular Profile of Marek’s Disease Virus Serotype 1 From Kampung and Arabic Chicken Farms in Sukabumi, West Java, Indonesia

Hayati Journal of Biosciences, 2016
There is an increasing trend to use molecular approaches to the study of Marek’s disease virus serotype 1 (MDV-1), the causative agent for the neoplastic syndrome of chickens known as Marek’s disease.
Risza Hartawan, Ni Luh Putu Indi Dharmayanti   +1 more
doaj   +1 more source

Differential cytokine responses following Marek's disease virus infection in chicken genotypes differing in resistance to Marek's disease [PDF]

, 2003
The production of cytokine mRNAs, in addition to viral DNA, was quantified by real-time quantitative reverse transcription-PCR (RT-PCR) (cytokines) or PCR (virus) in splenocytes during the course of Marek's disease virus (MDV) infection in four inbred ...
Davison, T F, Kaiser, Pete, Underwood, G
core   +1 more source

The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes [PDF]

, 2019
Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs.
Bertzbach, Luca D., Härtle, Sonja, Höper, Dirk, Karger, Axel, Kaufer, Benedikt B., Kheimar, Ahmed M., Pauker, Viktoria I., Pfaff, Florian   +7 more
core   +2 more sources

The extraordinary evolutionary history of the reticuloendotheliosis viruses [PDF]

, 2013
The reticuloendotheliosis viruses (REVs) comprise several closely related amphotropic retroviruses isolated from birds. These viruses exhibit several highly unusual characteristics that have not so far been adequately explained, including their extremely
A Katzourakis, A Katzourakis, A Stamatakis, AC van der Kuyl, AD Yoder, AL Hughes, AM Awad, AM Fadly, Anna Maria Niewiadomska, Bill Sugden, BR Burmester, C Feschotte, C Hertig, CG Ludford, CG Ludford, CN Dren, CN Dren, CN Dren, CR Parrish, CY Kang, CY Lin, DC Nickle, DH Huson, DH Ley, DJ McGeoch, DS Arathy, DW Trampel, E Prukner-Radovcic, EH Dearborn, F Abascal, F Rodriguez, FR Robinson, H Koyama, HC Carlson, HG Purchase, HM Koo, I Davidson, IS Diallo, IS Diallo, J Hanson, J Li, J Martin, JJ Solomon, JP Stoye, JP Vanderberg, JS McDougall, K Nyakatura, KA Schat, KM Moore, LA Terzian, LE Hayes, LJ Yu, LT Coggeshall, M Barbacid, M Garcia, MJ Peterson, MK Cook, ML Drew, MR Patel, MW Dimmic, MX Motha, N Ratnamohan, N Yuasa, P Singh, PE Miller, PS Paul, PS Sarma, Q Liu, R Crespo, R Gifford, R Isfort, RA Weiss, RB Franklin, RB Franklin, RJ Isfort, RL Witter, RL Witter, RL Witter, RM Corwin, Robert J. Gifford, SB Hitchner, SK Biswas, SL Kosakovsky Pond, T Barbosa, T Tadese, TJ Kim, TM Grimes, VN Kewalramani, W Trager, WG Conway, WH Cheng, Y Wang, Z Cheng, Z Cui, Z Yang, É Brumpt   +95 more
core   +3 more sources