Results 21 to 30 of about 4,947 (174)

The extraordinary evolutionary history of the reticuloendotheliosis viruses [PDF]

open access: yes, 2013
The reticuloendotheliosis viruses (REVs) comprise several closely related amphotropic retroviruses isolated from birds. These viruses exhibit several highly unusual characteristics that have not so far been adequately explained, including their extremely
A Katzourakis   +95 more
core   +3 more sources

First molecular detection and characterization of Marek’s disease virus in red-crowned cranes (Grus japonensis): a case report

open access: yesBMC Veterinary Research, 2018
Background Marek’s disease virus (MDV) resides in the genus Mardivirus in the family Herpesviridae. MDV is a highly contagious virus that can cause neurological lesions, lymphocytic proliferation, immune suppression, and death in avian species, including
Xue Lian   +8 more
doaj   +1 more source

Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E2 [PDF]

open access: yes, 2019
Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens. Here, we discovered that MDV activates the fatty acid synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEFs).
Behboudi, Shahriar   +3 more
core   +1 more source

Rho-ROCK and Rac-PAK signaling pathways have opposing effects on the cell-to-cell spread of Marek's Disease Virus. [PDF]

open access: yes, 2012
Marek's Disease Virus (MDV) is an avian alpha-herpesvirus that only spreads from cell-to-cell in cell culture. While its cell-to-cell spread has been shown to be dependent on actin filament dynamics, the mechanisms regulating this spread remain largely ...
Blondeau, C   +5 more
core   +10 more sources

Isolation and molecular characterization of a virulent Marek’s Disease virus serotype-1from Andhra Pradesh, India

open access: yesVeterinaria Italiana, 2021
Marek’s disease (MD) is one of the most significant neoplastic diseases of poultry caused by Marek’s disease virus (MDV), an oncogenic avian herpesvirus which is responsible for great economic losses to the poultry industry worldwide.
Prathiba Yanamala   +3 more
doaj   +1 more source

Immunological basis of differences in disease resistance in the chicken [PDF]

open access: yes, 2002
Genetic resistance to diseases is a multigenic trait governed mainly by the immune system and its interactions with many physiologic and environmental factors.
Gruys, E.   +5 more
core   +2 more sources

Role of Virus-Encoded microRNAs in Avian Viral Diseases

open access: yesViruses, 2014
With total dependence on the host cell, several viruses have adopted strategies to modulate the host cellular environment, including the modulation of microRNA (miRNA) pathway through virus-encoded miRNAs.
Yongxiu Yao, Venugopal Nair
doaj   +1 more source

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding. [PDF]

open access: yes, 2015
Highly polymorphic major histocompatibility complex (MHC) molecules are at the heart of adaptive immune responses, playing crucial roles in many kinds of disease and in vaccination. We report that breadth of peptide presentation and level of cell surface
A Madrigal (7759361)   +19 more
core   +6 more sources

Isolation and Molecular Detection of Marek’s Disease Virus from Outbreak Cases in Chicken in South Western Ethiopia

open access: yesVeterinary Medicine: Research and Reports, 2022
Abdela Bulbula,1 Bizunesh Borena,2 Biniam Tadesse,1 Abde Aliy,1 Demessa Negessu1 1Department of Bacterial Serology, Animal Health Institute (AHI), Sebeta, Oromia, Ethiopia; 2Department of Veterinary Laboratory Technology, Ambo University, Ambo, Oromia ...
Bulbula A   +4 more
doaj  

The dominantly expressed class II molecule from a resistant MHC haplotype presents only a few Marek's disease virus peptides by using an unprecedented binding motif.

open access: yesPLoS Biology, 2021
Viral diseases pose major threats to humans and other animals, including the billions of chickens that are an important food source as well as a public health concern due to zoonotic pathogens.
Samer Halabi   +9 more
doaj   +1 more source

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