Results 41 to 50 of about 2,397 (132)

Marek Disease Virus in Serbia: Detection and Molecular Characterization (2015 – 2022)

open access: yesActa Veterinaria
Out of 236 samples collected from clinically suspected farms and yards, the genome of Marek’s disease virus was detected in 84 (35.59 %) samples. Results showed the significant prevalence of the virus in intensive production/commercial farms (92.86 % of ...
Maletić Jelena   +6 more
doaj   +1 more source

Rapid, Sensitive, and Species-Specific Detection of Conventional and Recombinant Herpesvirus of Turkeys Vaccines Using Loop-Mediated Isothermal Amplification Coupled With a Lateral Flow Device Readout

open access: yesFrontiers in Veterinary Science, 2022
Marek's disease, an economically important disease of chickens caused by virulent serotype 1 strains of the Mardivirus Marek's disease virus (MDV-1), is effectively controlled in the field by live attenuated vaccine viruses including herpesvirus of ...
Giulia Mescolini   +3 more
doaj   +1 more source

Unraveling Oral Dysbiosis: Microbial Complexity in Common Oral Diseases

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
The oral microbiome undergoes dynamic establishment from birth, maturing into a resilient ecosystem. Perturbation of this homeostasis—driven by dietary, immunological, and anatomical factors—triggers dysbiosis, which underpins the pathogenesis of major oral diseases, including dental caries, periodontal disease, salivary gland disorders, oral mucosal ...
Zixi Kang   +8 more
wiley   +1 more source

Farmed Escapees Threaten MHC Diversity in Wild Atlantic Salmon

open access: yesEvolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Wild Atlantic salmon populations in Norway and elsewhere are experiencing long‐term declines driven by reduced marine survival, climate change, impacts from aquaculture, introduction of alien species, and environmental degradation. Understanding how immune diversity is affected by these declines, and thus the ability of Atlantic salmon to ...
Morten Lukacs   +9 more
wiley   +1 more source

A Common Live-Attenuated Avian Herpesvirus Vaccine Expresses a Very Potent Oncogene

open access: yesmSphere, 2019
Vaccines play a crucial role in the protection of animals and humans from deadly pathogens. The first vaccine that also protected against cancer was developed against the highly oncogenic herpesvirus Marek’s disease virus (MDV).
Andelé M. Conradie   +4 more
doaj   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

open access: yesJPGN Reports, Volume 7, Issue 2, Page 266-270, May 2026.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source

DIAGNOSTIC VALUE OF AGAR GEL PRECIPITATION TEST WITH FEATHER TIPS IN DIAGNOSIS OF MAREK'S DISEASE

open access: yesAssiut Veterinary Medical Journal, 2006
  In most cases, diagnosis of Marek's disease "MD" can be made on the basis of history, clinical signs and the presence of gross and microscopic lesions (Payne and Venugopal., 2000; Witter and Schat., 2003). However, in certain cases, additional tests e.
A.M.E. ASWAY
doaj   +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

open access: yesMovement Disorders, Volume 41, Issue 5, Page 1128-1140, May 2026.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step   +680 more
wiley   +1 more source

Discordance of Dopaminergic Dysfunction and Subcortical Atrophy by α‐Synuclein Status in Sporadic and Genetic Parkinson's Disease

open access: yesMovement Disorders, Volume 41, Issue 5, Page 1101-1113, May 2026.
Abstract Background Parkinson's disease (PD) is characterized by predominantly neuronal α‐synuclein pathology and dopaminergic dysfunction. Cerebrospinal fluid (CSF) seeding amplification assays (SAA) detect α‐synuclein aggregates in vivo, but not all patients with PD have a positive SAA.
Michael Tran Duong   +186 more
wiley   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab‐binding domain

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska   +6 more
wiley   +1 more source

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