Results 41 to 50 of about 5,051 (176)

Genotype-Dependent Tumor Regression in Marek’s Disease Mediated at the Level of Tumor Immunity [PDF]

, 2008
Research Article published by SpringerMarek’s disease (MD) of chickens is a unique natural model of Hodgkin’s and Non Hodgkin’s lymphomas in which the neoplastically-transformed cells over-express CD30 (CD30hi) antigen.
Shyamesh Kumar, Joram J. Buza, Shane C. Burgess, A Jemal, SC Burgess, JJ Buza, LA Shack, SC Burgess, AS Abdelrazeq, SC Burgess, SC Burgess, A O’Garra, W Hansen, AG Jarnicki, S Pfoertner, D Kabelitz, H Liu, T Mizobuchi, S Dominitzki, L Rothwell, MG Kaiser, P Kaiser, I Eldaghayes, FM McCarthy, KA Schat, Z Xing, Z Xing, MF Abdul-Careem, P Quere, PA Antony, AM Levy, LF Lu, K Miyazono, YP Rubtsov, J Marx, GL Hold, T Okamoto, R Horie, B Herreros, BF Skinnider, O Cochet, K Jurianz, T Alvaro, T Alvaro, BE Wahlin, K Chamoto   +45 more
core   +1 more source

Modeling Marek's disease virus transmission: A framework for evaluating the impact of farming practices and evolution

Epidemics, 2018
Marek's disease virus (MDV) is a pathogen of chickens whose control has twice been undermined by pathogen evolution. Disease ecology is believed to be the main driver of this evolution, yet mathematical models of MDV disease ecology have never been ...
David A. Kennedy, Patricia A. Dunn, Andrew F. Read   +2 more
doaj   +1 more source

Assessment of the dynamics of microparasite infections in genetically homogeneous and heterogeneous populations using a stochastic epidemic model [PDF]

, 2008
The aim of this paper was to explore the effect of genetic heterogeneity in host resistance to infection on the population-level risks and outcomes of epidemics.
Bishop, S. C., Nath, M., Woolliams, J. A.   +2 more
core   +1 more source

Coinfection in the host can result in functional complementation between live vaccines and virulent virus

Virulence, 2022
One of the greatest achievements of the last century is the development of vaccines against viral diseases. Vaccines are essential for battling infectious diseases and many different formulations are available, including live attenuated vaccines. However,
Huai Xu, Andrea L. Krieter, Nagendraprabhu Ponnuraj, Yvette (Yung-Tien) Tien, Taejoong Kim, Keith W. Jarosinski   +5 more
doaj   +1 more source

Integrated Genomic Approaches to Enhance Genetic Resistance in Chickens [PDF]

, 2013
The chicken has led the way among agricultural animal species in infectious disease control and, in particular, selection for genetic resistance. The generation of the chicken genome sequence and the availability of other empowering tools and resources ...
Cheng, Hans, Kaiser, Pete, Lamont, Susan, Lamont, Susan   +3 more
core   +3 more sources

Rho-ROCK and Rac-PAK signaling pathways have opposing effects on the cell-to-cell spread of Marek's Disease Virus. [PDF]

, 2012
Marek's Disease Virus (MDV) is an avian alpha-herpesvirus that only spreads from cell-to-cell in cell culture. While its cell-to-cell spread has been shown to be dependent on actin filament dynamics, the mechanisms regulating this spread remain largely ...
Blondeau, C, Denesvre, C, Richerioux, N, Rémy, S, Vautherot, JF, Wiedemann, A   +5 more
core   +10 more sources

A novel method for genome-wide profiling of dynamic host-pathogen interactions using 3′ end enriched RNA-seq

Scientific Reports, 2017
Marek’s disease is a contagious lymphoproliferative disease of chickens and typical model of viral oncogenesis. Mapping changes or different states over the course of infection for both host and pathogen would provide important insights into dynamic host-
Jie Li, Liangliang He, Yun Zhang, Chunyi Xue, Yongchang Cao   +4 more
doaj   +1 more source

Modulation of Functional Activities of Chicken Heterophils by Recombinant Chicken IFN-γ [PDF]

, 2001
The objective of the present studies was to examine the in vitro effects of recombinant chicken interferon-γ (rChIFN-γ) on shape change, phagocytosis, and the oxidative/nonoxidative killing activities of day-old chicken heterophils.
B. Kaspers, E.J. Pishko, HARMON B.G., K.C. Weining, KLEIN J.B., KOGUT M.H., KOGUT M.H., LEINO L., M.H. Kogut, MERRILL G.A., SETO F., STICKLE J.F., WEINING K.C.   +12 more
core   +1 more source

An Overview on Marek’s Disease Virus Evolution and Evidence for Increased Virulence in Brazil

Brazilian Journal of Poultry Science, 2019
Marek’s disease virus (MDV) has been shown to be evolving to higher virulence. One of the genetic sites involved in virulence which enables such characterization is the 339-amino acid Meq protein encoding gene (meq).
ACD Torres, SY Marin, CS Costa, NRS Martins   +3 more
doaj   +1 more source

Comparative genetic resistance to Ascaridia galli infections of 4 different commercial layer-lines [PDF]

, 2003
1. The objective of the study was to compare the establishment and effect of Ascaridia galli infections in 4 different layer-lines. 2. A total of 160 birds comprising 4 different commercial layer-lines, ISA Brown, New Hampshire, Skalborg and a cross of ...
Kjaer, J., Permin, A., Roepstorff, A., Schou, T., Sorensen, P.   +4 more
core   +1 more source