Marek’s disease virus - Open Access .click

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MOLECULAR CHARACTERIZATION AND HISTOPATHOLOGICAL ANALYSIS OF AVIAN RETICULOENDOTHELIOSIS VIRUS FROM GUINEA FOWL IN TAMIL NADU [PDF]

Exploratory Animal and Medical Research
The present study was carried out to detect the causative agent of sudden death in guinea fowl f lock maintained at organized poultry farm, Orathanadu. On post mortem examination, liver was enlarged and revealed multiple grayish areas.
P. Ponnusamy
doaj +1 more source

DNMT gene expression and methylome in Marek’s disease resistant and susceptible chickens prior to and following infection by MDV [PDF]

, 2013
Marek’s disease (MD) is characterized as a T cell lymphoma induced by a cell-associated α-herpesvirus, Marek’s disease virus type 1 (MDV1). As with many viral infectious diseases, DNA methylation variations were observed in the progression of MD; these ...
Edwards, John R +7 more
core +2 more sources

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

Movement Disorders, Volume 41, Issue 5, Page 1128-1140, May 2026.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step +680 more
wiley +1 more source

Rapid, Sensitive, and Species-Specific Detection of Conventional and Recombinant Herpesvirus of Turkeys Vaccines Using Loop-Mediated Isothermal Amplification Coupled With a Lateral Flow Device Readout

Frontiers in Veterinary Science, 2022
Marek's disease, an economically important disease of chickens caused by virulent serotype 1 strains of the Mardivirus Marek's disease virus (MDV-1), is effectively controlled in the field by live attenuated vaccine viruses including herpesvirus of ...
Giulia Mescolini +3 more
doaj +1 more source

The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV) [PDF]

, 2013
In contrast to typical mammals, the chicken MHC (the BF-BL region of the B locus) has strong genetic associations with resistance and susceptibility to infectious pathogens as well as responses to vaccines.
Butter, Colin +4 more
core +1 more source

Discordance of Dopaminergic Dysfunction and Subcortical Atrophy by α‐Synuclein Status in Sporadic and Genetic Parkinson's Disease

Movement Disorders, Volume 41, Issue 5, Page 1101-1113, May 2026.
Abstract Background Parkinson's disease (PD) is characterized by predominantly neuronal α‐synuclein pathology and dopaminergic dysfunction. Cerebrospinal fluid (CSF) seeding amplification assays (SAA) detect α‐synuclein aggregates in vivo, but not all patients with PD have a positive SAA.
Michael Tran Duong +186 more
wiley +1 more source

Marek Disease Virus in Serbia: Detection and Molecular Characterization (2015 – 2022)

Acta Veterinaria
Out of 236 samples collected from clinically suspected farms and yards, the genome of Marek’s disease virus was detected in 84 (35.59 %) samples. Results showed the significant prevalence of the virus in intensive production/commercial farms (92.86 % of ...
Maletić Jelena +6 more
doaj +1 more source

Early replication in pulmonary B cells after infection with marek's disease herpesvirus by the respiratory route [PDF]

, 2009
Natural infection with Marek's disease virus occurs through the respiratory mucosa after chickens inhale dander shed from infected chickens. The early events in the lung following exposure to the feather and squamous epithelial cell debris containing the
Adldinger H +20 more
core +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab‐binding domain

Protein Science, Volume 35, Issue 5, May 2026.
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska +6 more
wiley +1 more source

Advances in Avian Diagnostic Pathology: Current Trends, Challenges and Future Directions: A Review

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Advances in avian diagnostic pathology integrate histopathology, immunohistochemistry, molecular diagnostics and digital pathology to enhance the detection and management of poultry diseases. Emerging tools, including machine learning and artificial intelligence, further improve diagnostic accuracy, disease surveillance and outbreak prediction.
Gebyaw Menge Getnet +2 more
wiley +1 more source

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