Results 51 to 60 of about 2,342 (132)

Naturally Occurring Co-infection of Avian Leukosis Virus (subgroups A-E) and Reticuloendotheliosis Virus in Green Peafowls (Pavo muticus)

open access: yesBrazilian Journal of Poultry Science
Most of the neoplastic diseases affecting poultry have a viral etiology, such as Marek’s disease, avian leukosis/sarcoma and reticuloendotheliosis. In the present paper, histopathology and molecular methods were performed, in addition of necropsy and ...
M Khordadmehr   +3 more
doaj   +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

open access: yesMovement Disorders, Volume 41, Issue 5, Page 1128-1140, May 2026.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step   +680 more
wiley   +1 more source

Discordance of Dopaminergic Dysfunction and Subcortical Atrophy by α‐Synuclein Status in Sporadic and Genetic Parkinson's Disease

open access: yesMovement Disorders, Volume 41, Issue 5, Page 1101-1113, May 2026.
Abstract Background Parkinson's disease (PD) is characterized by predominantly neuronal α‐synuclein pathology and dopaminergic dysfunction. Cerebrospinal fluid (CSF) seeding amplification assays (SAA) detect α‐synuclein aggregates in vivo, but not all patients with PD have a positive SAA.
Michael Tran Duong   +186 more
wiley   +1 more source

Structural and functional insights into TBC1D17 highlight the importance of the previously uncharacterized Rab‐binding domain

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract TBC (Tre2/Bub2/Cdc16) domain‐containing proteins constitute the widespread family of GTPase‐activating proteins (GAPs). They interact with the Rab superfamily of small GTPases, stimulate GTP hydrolysis, and regulate vesicle trafficking. TBC1D17, involved in Shiga toxin trafficking, autophagy and glucose metabolism regulation, constitutes an ...
Dominika Nielipińska   +6 more
wiley   +1 more source

Advances in Avian Diagnostic Pathology: Current Trends, Challenges and Future Directions: A Review

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Advances in avian diagnostic pathology integrate histopathology, immunohistochemistry, molecular diagnostics and digital pathology to enhance the detection and management of poultry diseases. Emerging tools, including machine learning and artificial intelligence, further improve diagnostic accuracy, disease surveillance and outbreak prediction.
Gebyaw Menge Getnet   +2 more
wiley   +1 more source

Silent pressure: Unveiling spinal lymphoma in horses and its parallels to other species

open access: yesEquine Veterinary Education, Volume 38, Issue 5, Page 231-234, May 2026.
Summary Though the nervous system is an uncommon location for lymphoma, the disease should remain a differential diagnosis in some cases of ataxia in equids. Diagnosis of lymphoma can be challenging, although a combination of cytology, histopathology and immunophenotyping can aid in definitive diagnosis and therefore more accurately guide treatment and
H. E. Taylor, D. Luethy
wiley   +1 more source

Viral miRNA delivered by exosomes from Marek's disease virus-transformed lymphoma cell line exerts regulatory function in internalized primary chicken embryo fibroblast cells

open access: yesTumour Virus Research
In the past decade, research has demonstrated that viral miRNAs encoded by a number of viral genomes, particularly by most of the herpesvirus including Marek's disease virus (MDV), play important regulatory roles in viral infection, replication, and ...
Man Teng   +6 more
doaj   +1 more source

Use o fDulbecco's modified eagle's medium DMEM/F12 HAM for Marek's disease virus cultivation in chicken embryo fibroblasts

open access: yesВетеринария сегодня, 2018
The opportunity of using Dulbecco's Modified Eagle's Medium DMEM/F12 Ham for Marek's disease cultivation in chicken embryo fibroblasts was studied. It was determined that if appropriate virus cultivation parameters are chosen the abovementioned medium ...
Ye. Yu. Khanyukova   +2 more
doaj  

Marek’s Disease Virus Infection of Natural Killer Cells

open access: yesMicroorganisms, 2019
Natural killer (NK) cells are key players in the innate immune response. They kill virus-infected cells and are crucial for the induction of adaptive immune responses. Marek's disease virus (MDV) is a highly contagious alphaherpesvirus that causes deadly
Luca D. Bertzbach   +4 more
doaj   +1 more source

A novel protein-coding ORF72.2 gene was identified from Marek's disease virus strain CVI988

open access: yesVirology Journal, 2010
Marek's disease is a highly contagious disease of poultry characterized by rapid-on set of T-cell lymphomas, which is caused by Marek's disease virus (MDV), but its pathogenic mechanism is still not very clear.
Liu Ping   +8 more
doaj   +1 more source

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