Results 51 to 60 of about 2,392 (131)

Decoding the Black Box of Fish Vaccines Efficacy in Basic and Applied Contexts

Reviews in Aquaculture, Volume 18, Issue 4, September 2026.
ABSTRACT Vaccines are the frontline defense in aquaculture, yet predicting their real‐world performance remains a tricky puzzle. Unlike terrestrial veterinary vaccines, fish vaccines largely operate through “Black Box” processes, where we observe the outcomes but rarely understand the underlying immune mechanisms. Laboratory trials, though informative,
Jiří Kyslík, Mikolaj Adamek, Tomáš Korytář   +2 more
wiley   +1 more source

Naturally Occurring Co-infection of Avian Leukosis Virus (subgroups A-E) and Reticuloendotheliosis Virus in Green Peafowls (Pavo muticus)

Brazilian Journal of Poultry Science
Most of the neoplastic diseases affecting poultry have a viral etiology, such as Marek’s disease, avian leukosis/sarcoma and reticuloendotheliosis. In the present paper, histopathology and molecular methods were performed, in addition of necropsy and ...
M Khordadmehr, M Firouzamandi, M Zehtab-Najafi, R Shahbazi   +3 more
doaj   +1 more source

First‐line treatment with epcoritamab in combination with bendamustine plus rituximab induces sustained remissions beyond 3 years in patients with follicular lymphoma

HemaSphere, Volume 10, Issue 8, August 2026.
Abstract First‐line (1L) bendamustine plus rituximab (BR) leads to high response rates in follicular lymphoma (FL), but maintaining durable remissions remains challenging. We report the 3‐year follow‐up from arm 3 of the phase 1b/2 EPCORE NHL‐2 trial (NCT04663347) of epcoritamab, a subcutaneously administered CD3×CD20 bispecific antibody, combined with
Umberto Vitolo, Lorenzo Falchi, Per‐Ola Andersson, Marcel Nijland, Fritz Offner, Sylvia Snauwaert, Jacob H. Christensen, Michael R. Clausen, Alexander Fosså, Pilar G. Prieto, Eliza A. Hawkes, Judit M. Jørgensen, Yasmin H. Karimi, Catharina Lewerin, Joost S. P. Vermaat, Björn E. Wahlin, Poliana Patah, Christopher Morehouse, Malene Risum, Zhu Li, Jennifer Marek, Joshua D. Brody   +21 more
wiley   +1 more source

Suspected lymphoid leukosis visceral lymphoma with intestinal and ovarian involvement in a chicken

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract An adult hen from a small poultry flock was submitted for diagnostic investigation because of nonspecific clinical disease and suspected neoplasia. At necropsy, the bird had ascites, splenomegaly, severe intestinal adhesions, nodular intestinal lesions and ovarian masses. Histopathology revealed extensive infiltration of the intestinal mucosa,
Thomas Salles Dias, Taís da Silva Lopes Chagas, Davi Lemos Monteiro, Carlos Henrique Campello Costa, Aniesse Siva Aguiar, Dayse Lima da Costa Abreu   +5 more
wiley   +1 more source

Instance of a Heteroplasmic Mitogenome in Alvinocaridid Shrimp Mirocaris fortunata (Martin & Christiansen 1995) Found at the Moytirra Deep‐Sea High‐Temperature Hydrothermal Vent Field

Ecology and Evolution, Volume 16, Issue 7, July 2026.
First complete mitochondrial genome of the deep‐sea hydrothermal vent shrimp Mirocaris fortunata (Alvinocarididae) from shotgun sequencing data on an individual tail tissue. The 15,923‐bp‐long sequence displays 98.72% pairwise identity with its closest relative, Mirocaris indica.
Paola E. Campos, Patrick C. Collins, Aoife Ruane, Jeanette E. Carlsson, Jens Carlsson   +4 more
wiley   +1 more source

Viral miRNA delivered by exosomes from Marek's disease virus-transformed lymphoma cell line exerts regulatory function in internalized primary chicken embryo fibroblast cells

Tumour Virus Research
In the past decade, research has demonstrated that viral miRNAs encoded by a number of viral genomes, particularly by most of the herpesvirus including Marek's disease virus (MDV), play important regulatory roles in viral infection, replication, and ...
Man Teng, Jun Luo, Yaoyao Zhang, Vishwanatha R.A.P. Reddy, Priya Samuel, Yongxiu Yao, Venugopal Nair   +6 more
doaj   +1 more source

Use o fDulbecco's modified eagle's medium DMEM/F12 HAM for Marek's disease virus cultivation in chicken embryo fibroblasts

Ветеринария сегодня, 2018
The opportunity of using Dulbecco's Modified Eagle's Medium DMEM/F12 Ham for Marek's disease cultivation in chicken embryo fibroblasts was studied. It was determined that if appropriate virus cultivation parameters are chosen the abovementioned medium ...
Ye. Yu. Khanyukova, M. A. Shustova, H. Ye. Kamalova   +2 more
doaj  

Marek’s Disease Virus Infection of Natural Killer Cells

Microorganisms, 2019
Natural killer (NK) cells are key players in the innate immune response. They kill virus-infected cells and are crucial for the induction of adaptive immune responses. Marek's disease virus (MDV) is a highly contagious alphaherpesvirus that causes deadly
Luca D. Bertzbach, Daphne A. van Haarlem, Sonja Härtle, Benedikt B. Kaufer, Christine A. Jansen   +4 more
doaj   +1 more source

A novel protein-coding ORF72.2 gene was identified from Marek's disease virus strain CVI988

Virology Journal, 2010
Marek's disease is a highly contagious disease of poultry characterized by rapid-on set of T-cell lymphomas, which is caused by Marek's disease virus (MDV), but its pathogenic mechanism is still not very clear.
Liu Ping, Zou Nianli, Lin Yan, Shi Min, Zhao Yang, Tian Mingxing, Wen Xintian, Cao Sanjie, Huang Yong   +8 more
doaj   +1 more source

Protection study of the Labio-Marek vaccine against the JM strain challenge in SPF chickens

VacciMonitor, 2014
Marek's disease is a lymphomatous and neuropathic disease of the domestic chickens caused by herpesvirus. Currently the acute form of the disease, with extended visceral lymphomas, is the most common with an incidence of 10-30%.
Mayelin Paneque-Sayas, Digna Contreras-González, Anniet Fresneda, Gladys Proenza, Tania Irene Tabares- Beltrán, Eloy Diaz-Fernández   +5 more
doaj