Results 141 to 150 of about 21,237,081 (159)

Association of Low Serum Maresin-1 Levels with Hepatocellular Carcinoma in Cirrhotic Liver

Clinical Laboratory
Maresin-1 (MaR1) is a macrophage-derived antiinflammatory lipid mediator that negatively regulates oxidative and proinflammatory cytokines and also restores integrity in various tissues after inflammation. Non-resolving inflammation is known to have an important role in the pathogenesis of hepatocellular carcinoma (HCC).
Ergül, Bilal, Gül, Özlem, Kisa, Üçler, Erdal, Harun, Tekin, Ercan, Oğuz, Dilek   +5 more
openaire   +3 more sources

Maresin 1 activates brown adipocytes metabolism

2018
Brown adipose tissue (BAT) is the main site for adaptive heat production through non-shivering thermogenesis. BAT has been brought to attention, since it provides a protective mechanism against excessive body weight and fat mass accumulation. Recently, it has been suggested emerging roles of BAT activation in the regulation of metabolism, including ...
Laiglesia, Laura M., Escoté, Xavier, Valverde, Ángela M., Moreno-Aliaga, María Jesús   +3 more
openaire   +1 more source

Maresin 1 mitigates liver steatosis in ob/ob and diet-induced obese mice

International Journal of Obesity, 2017
The aim of this study was to characterize the effects of Maresin 1 (MaR1) in obesity-related liver steatosis and the mechanisms involved.MaR1 effects on fatty liver disease were tested in ob/ob (2-10 μg kg-1 i.p., 20 days) and in diet-induced obese (DIO) mice (2 μg kg-1, i.p., or 50 μg kg-1, oral gavage for 10 days), as well as in cultured hepatocytes ...
L M, Laiglesia, S, Lorente-Cebrián, L, Martínez-Fernández, N, Sáinz, P L, Prieto-Hontoria, M A, Burrell, C M, Rodríguez-Ortigosa, J A, Martínez, M J, Moreno-Aliaga   +8 more
openaire   +2 more sources

1523 Topical maresin-1 impairs wound healing

Journal of Investigative Dermatology, 2023
R. Takayanagi, Y. Sawada, E. Okada
openaire   +1 more source

Maresin-1 and its receptors RORα/LGR6 as potential therapeutic target for respiratory diseases

Pharmacological Research, 2022
Mengmeng Zhao, Zheng Yin, Zihui Zheng
exaly  

Maresin-1 suppresses IL-1β-induced MMP-13 secretion by activating the PI3K/AKT pathway and inhibiting the NF-κB pathway in synovioblasts of an osteoarthritis rat model with treadmill exercise

Connective Tissue Research, 2021
Xinyuan Feng, Yingliang Wei, Lunhao Bai   +2 more
exaly  

ISID1523 - Topical maresin-1 impairs wound healing

2023
Yu Sawada, Reiko Hara
openaire   +1 more source

Maresin-1 improves LPS-induced depressive-like behavior by inhibiting hippocampal microglial activation

Journal of Affective Disorders, 2023
Zhu Xia, Jiamei Guo, Dachuan Qiu
exaly  

[Research progress on the organ-protective effect of Maresin-1 in sepsis].

Zhonghua wei zhong bing ji jiu yi xue
Sepsis is a fatal organ dysfunction caused by the uncontrolled inflammatory response of the host to infection. Excessive inflammatory reaction is the core factor in the occurrence and development of sepsis, the degree of organ dysfunction is directly related to the prognosis of sepsis.
Lili, Tang, Gong, Moxiang, Qiao, Chen, Zhiyong, Su, Xiaoyue, Li   +4 more
openaire   +1 more source

Maresin 1 alleviates sevoflurane-induced neuroinflammation in neonatal rats via JAK2/STAT3/IL-6 pathways

International Immunopharmacology, 2022
Zhipeng Sun
exaly