Results 51 to 60 of about 606 (121)
Spironolactone Attenuates Experimental Uremic Cardiomyopathy by Antagonizing Marinobufagenin
, 2009 Spironolactone has been noted to attenuate cardiac fibrosis. We have observed that the cardiotonic steroid marinobufagenin plays an important role in the diastolic dysfunction and cardiac fibrosis seen with experimental renal failure.
Gupta, Shalini +14 more
core
, 2019 Purpose of Review This review synthesizes recent findings in humans pertaining to the relationships between marinobufagenin (MBG), a steroidal Na+/K+-ATPase inhibitor and salt-sensitivity biomarker, and early cardiovascular risk markers.
Strauss, M +3 more
core +1 more source
The role of Angiotensin converting Enzyme 2 and Marinobufagenin in Leptin induced Hypertension and Proteinuria during Pregnancy in Sprague Dawley Rats / Maryam Jameelah Md Hassan [PDF]
, 2019 Leptin administration to pregnant rats increases systolic blood pressure (SBP), urinary protein excretion and markers of endothelial activation. Although the precise mechanism for this remains unclear, marinobufagenin (MBG) has been implicated in some ...
Md Hassan, Maryam Jameelah
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Large artery stiffness is associated with marinobufagenin in young adults: the African-PREDICT study
, 2018 Objectives: The cardiotonic steroid, marinobufagenin (MBG), has been shown to play a physiological natriuretic role in response to salt intake. However, recent studies in clinical and animal models demonstrated possible links between elevated levels of ...
Wei, Wen +4 more
core +2 more sources
Analytical aspects of marinobufagenin and its applications in the diagnostic of preeclampsia
, 2012 Analytical aspects of marinobufagenin and its applications in the diagnostic of preeclampsia C. Lenaerts1, B. Blankert1 1 Laboratory of Pharmaceutical Analysis, Faculty of medicine and pharmacy, University of Mons, place du parc 20, 7000 Mons, Belgium.
Blankert, Bertrand, Lenaerts, Charline
core +1 more source
, 2017 Aim. Study of the influence of sodium chloride overconsumption by pregnant rats with induced diabetes mellitus on the synthesis of marinobufagenin and Na/K-ATPase activity. Methods. The study was performed on 72 female Sprague Dawley rats.
A Ya Bagrov +3 more
core +1 more source
Reduction of Na/K-ATPase Potentiates Marinobufagenin-induced Cardiac Dysfunction and Myocyte Apoptosis [PDF]
, 2012 Decreases in cardiac Na/K-ATPase have been documented in patients with heart failure. Reduction of Na/K-ATPase alpha 1 also contributes to the deficiency in cardiac contractility in animal models.
Wang, Yu +15 more
core +1 more source
Marinobufagenin : a new diagnosis target for preeclampsia syndrome?
, 2013 The bufadienolides, belonging to the cardiac glycosides class are present in humans as well as in some plants and animals. But the major source for these compounds is located in the parotid and skin gland secretions of some toad species, notably Bufo ...
Blankert, Bertrand, Lenaerts, Charline
core +1 more source
Analytical aspects of marinobufagenin and its applications in the diagnosis of preeclampsia [PDF]
, 2013 Introduction Marinobufagenin (MBG), a bufadienolide cardiac inotrope, enjoys a growing interest in the early diagnosis of volume expansion-mediated hypertensive states such as preeclampsia (PE).
Blankert, Bertrand +2 more
core +1 more source