Results 131 to 140 of about 427,345 (355)

Association Mapping for Common Bunt Resistance in Wheat [PDF]

open access: yes, 2013
Common bunt, caused by Tilletia caries and T. foetida, is a fungal disease of wheat world wide. Infection, occurring via seed borne teliospores, is generally controlled by the application of seed treatments prior to sowing.
Backes, Gunter   +3 more
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Precision of genetic parameters and breeding values estimated in marker assisted BLUP genetic evaluation

open access: yesGenetics Selection Evolution, 2009
In practical implementations of marker-assisted selection economic and logistic restrictions frequently lead to incomplete genotypic data for the animals of interest.
Thaller Georg   +4 more
doaj   +1 more source

SSRs for marker assisted selection for blast resistance in rice (Oryza sativa L.). [PDF]

open access: yes, 2012
Rice blast caused by the fungus Magnaporthe oryzae is one of the most devastating diseases of rice in nearly all rice growing areas of the world including Malaysia. To develop cultivars with resistance against different races of M.
Abdullah, Siti Nor Akmar   +6 more
core   +1 more source

Marker assisted selection ‐ an overview

open access: yesAnimal Biotechnology, 1994
Abstract The main force driving gene mapping in domestic animals, is the potential for using gene maps as a means of identifying and mapping the genetic loci responsible for genetic variation in traits of economic importance. The ultimate objective is utilizing this information for marker‐assisted selection (MAS) using DNA level polymorphisms.
openaire   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Association Analysis of SSR Markers with Phenology, Grain, and Stover-Yield Related Traits in Pearl Millet (Pennisetum glaucum (L.) R. Br.)

open access: yesThe Scientific World Journal, 2014
Pearl millet is a staple food crop for millions of people living in the arid and semi-arid tropics. Molecular markers have been used to identify genomic regions linked to traits of interest by conventional QTL mapping and association analysis. Phenotypic
Baskaran Kannan   +6 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

MOLECULAR MARKERS: IMPLEMENTATION IN CROP PLANT BREEDING FOR IDENTIFICATION, INTROGRESSION, AND GENE PYRAMIDING

open access: yesВавиловский журнал генетики и селекции, 2014
Over the past decades, wide theoretical and practical experience has been obtained in application of DNA markers for investigation of plant genetic diversity, construction of molecular genetic maps, mapping of genes and quantitative trait loci, and ...
I. N. Leonova
doaj  

Assessment of 18 Years of Genetic Marker-Assisted Selection and Augmentation of Native Walleye in the Upper New River, Virginia, USA

open access: yesFishes
Walleye Sander vitreus is a valued sportfish in eastern North America, including the upper New River of Virginia, where individuals can grow to a large size (>7 kg).
Sheila Harris   +4 more
doaj   +1 more source

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