Results 101 to 110 of about 46,299 (322)

Counter-regulatory RAS peptides: new therapy targets for inflammation and fibrotic diseases?

Frontiers in Pharmacology
The renin-angiotensin system (RAS) is an important cascade of enzymes and peptides that regulates blood pressure, volume, and electrolytes. Within this complex system of reactions, its counter-regulatory axis has attracted attention, which has been ...
Diana V. Ávila-Martínez, Diana V. Ávila-Martínez, Wendy K. Mixtega-Ruiz, Wendy K. Mixtega-Ruiz, José M. Hurtado-Capetillo, Oscar Lopez-Franco, Oscar Lopez-Franco, Mónica Flores-Muñoz, Mónica Flores-Muñoz   +8 more
doaj   +1 more source

The Novel Angiotensin-(1–7) Analog, A-1317, Improves Insulin Resistance by Restoring Pancreatic β-Cell Functionality in Rats With Metabolic Syndrome

Frontiers in Pharmacology, 2020
In previous studies we have shown that oral Ang-(1–7) has a beneficial therapeutic effect on cardiometabolic disturbances present in metabolic syndrome (MetS).
Maria Andréa Barbosa, Claudiane Maria Barbosa, Taynara Carolina Lima, Robson Augusto Souza dos Santos, Andréia Carvalho Alzamora, Andréia Carvalho Alzamora   +5 more
doaj   +1 more source

Hydronephrosis alters cardiac ACE2 and Mas receptor expression in mice

Journal of the Renin-Angiotensin-Aldosterone System, 2015
Introduction: Hydronephrosis is characterized by substantial loss of tubules and affects renin secretion in the kidney. However, whether alterations of angiotensin-converting enzyme (ACE), ACE2 and Mas receptor in the heart are observed in hydronephrosis is unknown.
Yanling, Zhang, Lulu, Ma, Junyan, Wu, Tingting, Chen   +3 more
openaire   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Papel do receptor ativado por proteinases-2 (par-2) no comportamento de coçar em camundongos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pos-Graduação em Farmacologia, Florianópolis, 2009.O objetivo do presente estudo foi investigar os possíveis mecanismos e mediadores envolvidos no
Costa, Robson da
core  

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Modulation of ACE2/Ang1-7/Mas and ACE/AngII/AT1 axes affects anticancer properties of sertraline in MCF-7 breast cancer cells

Biochemistry and Biophysics Reports
The renin–angiotensin system (RAS) is best known for playing a major role in maintaining the physiology of the cardiovascular system. Dysregulation of the RAS pathway has been proposed as a link to some malignancies and contributes to cancer metastasis ...
Reihaneh Fatehi, Mohammad Nouraei, Morteza Panahiyan, Marzieh Rashedinia, Negar Firouzabadi   +4 more
doaj   +1 more source

The interferon alpha receptor utilises T-cell receptor-associated proteins for signalling [PDF]

, 2009
The interferon alpha receptor (IFNAR) and T-cell receptor (TCR) are expressed upon the T-cell surface. The dimeric Class I interferon receptor is a cytokine receptor that recognises interferons such as IFNα.
Stevens, C.N., Stevens, C N
core  

Role of Angiotensin-(1-7) via MAS receptor in human sperm motility and acrosome reaction

, 2020
Rennin-angiotensin system (RAS) has been involved in sperm function, even so, little is known about the implication of one of the RAS axis formed by Ang-(1-7) (angiotensin-(1-7)) and MAS receptor. Hence, in the present work, we focused on elucidating the
Casis Sáenz, Luis, Aguirregoitia Marcos, Ekaitz, Beitia, Maider, Totorikaguena Iturriaga, Lide, Valdivia Palacin, Asier, Cortés Meler, Lorea, Matorras Weinig, José Roberto, Aguirregoitia Marcos, Naiara, Irazusta Astiazaran, Jon, Corcóstegui, Beatriz   +9 more
core   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source