Results 1 to 10 of about 45,545 (290)
Angiotensin-(1-7) and Mas receptor in the brain [PDF]
Exploration of Medicine, 2021 The renin-angiotensin system (RAS) is a key regulator of blood pressure and electrolyte homeostasis. Besides its importance as regulator of the cardiovascular function, the RAS has also been associated to the modulation of higher brain functions ...
Natalia L. Rukavina Mikusic +2 more
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Tubular Mas receptor mediates lipid-induced kidney injury [PDF]
Cell Death and Disease, 2021 Obesity-related kidney diseases are becoming serious health problems worldwide, yet the mechanism by which obesity causes kidney injury is not fully understood.
Yonglun Kong +10 more
doaj +3 more sources
Angiotensin-II type 2 receptor-mediated renoprotection is independent of receptor Mas in obese Zucker rats fed high-sodium diet [PDF]
Frontiers in PharmacologyThe consumption of a high-sodium diet (HSD) is injurious and known to elevate blood pressure (BP), especially in obesity. Acute infusion studies depict a functional interdependency between angiotensin-II type 2 receptor (AT2R) and receptor Mas (MasR ...
Sanket N. Patel +3 more
doaj +2 more sources
Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas [PDF]
Disease Models & Mechanisms, 2016 Immobilization is a form of disuse characterized by a loss of strength and muscle mass. Among the main features are decreased IGF-1/Akt signalling and increased ubiquitin-proteasome pathway signalling, which induce greater myosin heavy chain degradation.
María Gabriela Morales +9 more
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Angiotensin II Type 2 Receptor and Receptor Mas Are Colocalized and Functionally Interdependent in Obese Zucker Rat Kidney. [PDF]
Hypertension, 2017 Patel SN +4 more
europepmc +2 more sources
Experimental Physiology, 2023 This study investigated the action of angiotensin 1–7 (Ang (1–7)) on renal haemodynamic and excretory function in the two‐kidney one‐clip (2K1C) and deoxycorticosterone acetate (DOCA)‐salt rat models of hypertension, in which the endogenous renin ...
Elaine F. Barry +6 more
doaj +1 more source
Journal of Pharmacological Sciences, 2021 Roles of the renin-angiotensin system in autophagy and ischemia/reperfusion (I/R) injury in the kidney have not been fully characterized. Here we examined the hypothesis that modest activation of the angiotensin II (Ang II) receptor upregulates autophagy
Hirohito Sugawara +10 more
doaj +1 more source
Pharmacology Research & Perspectives, 2020 Angiotensin‐(1‐7), an endogenous agonist for the MasR, has been shown to interact with ang‐II AT1R and AT2R. Earlier we showed a physical and functional interaction between MasR and AT2R in response to their respective agonists ang‐(1‐7) and C21 ...
Sanket Patel, Tahir Hussain
doaj +1 more source
Emerging Microbes and Infections, 2021 Since December 2019, coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has changed our lives.
Serge Camelo +6 more
doaj +1 more source
Transactivation of ErbB Family of Receptor Tyrosine Kinases Is Inhibited by Angiotensin-(1-7) via Its Mas Receptor. [PDF]
PLoS ONE, 2015 Transactivation of the epidermal growth factor receptor (EGFR or ErbB) family members, namely EGFR and ErbB2, appears important in the development of diabetes-induced vascular dysfunction.
Saghir Akhtar +5 more
doaj +1 more source