Results 11 to 20 of about 2,253,320 (251)

Indoxyl sulfate downregulates expression of Mas receptor via OAT3/AhR/Stat3 pathway in proximal tubular cells. [PDF]

PLoS ONE, 2014
Renin-angiotensin system (RAS) plays a pivotal role in chronic kidney disease (CKD). Angiotensin converting enzyme-related carboxypeptidase 2 (ACE2)/angiotensin (Ang)-(1-7)/Mas receptor axis counteracts the deleterious actions of Ang II.
Hwee-Yeong Ng, Maimaiti Yisireyili, Shinichi Saito, Chien-Te Lee, Yelixiati Adelibieke, Fuyuhiko Nishijima, Toshimitsu Niwa   +6 more
doaj   +2 more sources

Dictamen jurídic en matèria d'urbanisme [PDF]

, 2022
Treballs Finals del Màster d'Advocacia, Facultat de Dret, Universitat de Barcelona, Curs: 2021-2022, Tutor: Tornos Mas ...
Aumatell i Mas, Jordi
core   +6 more sources

Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin Type 2 receptor [PDF]

, 2012
The counter-regulatory axis of the renin angiotensin system peptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a potential therapeutic target in cardiac remodelling, acting via the mas receptor.
Nicklin Stuart A., Almalik Abdulaziz, Bruno M D C Godinho, Flores-Muñoz Monica, Flores-Muñoz, M., Almalik, A., Nicklin, S.A., Monica Flores-Muñoz, Stuart A Nicklin, Abdulaziz Almalik, Godinho, B.M.D.C., Godinho Bruno M. D. C.   +11 more
core   +2 more sources

Human Mas-related G protein-coupled receptors-X1 induce chemokine receptor 2 expression in rat dorsal root ganglia neurons and release of chemokine ligand 2 from the human LAD-2 mast cell line [PDF]

, 2013
Primate-specific Mas-related G protein-coupled receptors-X1 (MRGPR-X1) are highly enriched in dorsal root ganglia (DRG) neurons and induce acute pain. Herein, we analyzed effects of MRGPR-X1 on serum response factors (SRF) or nuclear factors of activated
Kathrin Rothe (386395), Ingrid Boekhoff, Ingrid Boekhoff (180345), Andreas Breit (180329), Solinski Hans Jürgen, Petermann, Franziska, Andreas Breit, Hans Jürgen Solinski (166922), Rothe Kathrin, Thomas Gudermann, Franziska Petermann, Boekhoff, Ingrid, Breit, Andreas, Boekhoff Ingrid, Rothe, Kathrin, Gudermann, Thomas, Gudermann Thomas, Breit Andreas, Thomas Gudermann (77426), Hans Jürgen Solinski, Petermann Franziska, Franziska Petermann (220017), Solinski, Hans Jürgen, Kathrin Rothe   +23 more
core   +2 more sources

Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK1/2and cell proliferationviaGαq-mediated mechanism [PDF]

, 2014
Dimerization of G protein-coupled receptors (GPCRs) is crucial for receptor function including agonist affinity, efficacy, trafficking and specificity of signal transduction, including G protein coupling.
Cai, X, Jiang, Y, Karteris, E, Bai, B, Chen, J, Karteris, Emmanouil, Bai, Bo, Jiang, Yunlu, Cai, Xin, Chen, Jing   +9 more
core   +1 more source

Angiotensina-(1-7) durante o processo inicial na cascata da ovulação em bovinos Angiotensin-(1-7) during the initial process of ovulatory cascade in cattle

Ciência Rural, 2012
O presente estudo teve como objetivo avaliar o efeito da Ang-(1-7) e de seu receptor (MAS) na regulação da ovulação. No experimento I, utilizando um modelo in vitro de cultivo de células foliculares, foi avaliado o efeito do tratamento com Ang-(1-7) ou ...
Joabel Tonellotto dos Santos, Bernardo Garziera Gasperin, Vitor Braga Rissi, Matheus Pedrotti De Cesaro, Alfredo Skrebsky Cezar, João Francisco Coelho de Oliveira, Paulo Bayard Dias Gonçalves   +6 more
doaj   +1 more source

Control of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1L [PDF]

, 2014
Molecular chaperones encompass a group of unrelated proteins that facilitate the correct assembly and disassembly of other macromolecular structures, which they themselves do not remain a part of.
Cato, L., Neeb, A., Brown, Myles, Cato, Andrew C. B., Cato, A. C. B., Neeb, Antje, Brown, M., Cato, Laura   +7 more
core   +1 more source

Blockade of Mas Receptor or Mas-Related G-Protein Coupled Receptor Type D Reduces Portal Pressure in Cirrhotic but Not in Non-cirrhotic Portal Hypertensive Rats

Frontiers in Physiology, 2019
Portal hypertension (PHT) resulting from splanchnic vasodilatation is a major cause of morbidity and mortality in patients with cirrhosis. The renin-angiotensin system (RAS) plays an important role in splanchnic vasodilatation in cirrhosis.
Lakmie S. Gunarathne, Peter W. Angus, Peter W. Angus, Chandana B. Herath   +3 more
doaj   +1 more source

Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla [PDF]

, 2010
AIMS: Angiotensin(1-7) (Ang1-7) acting at the level of the rostral ventrolateral medulla (RVLM) affects arterial pressure. The cellular substrate of Ang1-7 remains unknown.
Tang, F, Fang Guo, Feige Tang, Samantha Lane, Souslova, E A, Ekaterina A. Souslova, Paton, JFR, Lane, S, Sergey Kasparov, Dmitriy M. Chudakov, Kasparov, S, Guo, F, Chudakov, D M, Liu, B, Beihui Liu, Julian F.R. Paton   +15 more
core   +1 more source

Angiotensin Receptors Heterodimerization and Trafficking: How Much Do They Influence Their Biological Function?

Frontiers in Pharmacology, 2020
G-protein–coupled receptors (GPCRs) are targets for around one third of currently approved and clinical prescribed drugs and represent the largest and most structurally diverse family of transmembrane signaling proteins, with almost 1000 members ...
Natalia L. Rukavina Mikusic, Mauro G. Silva, Angélica M. Pineda, Mariela M. Gironacci   +3 more
doaj   +1 more source