Results 31 to 40 of about 45,545 (290)
Frontiers in Immunology, 2021 ObjectivesRheumatoid arthritis (RA) is a disabling disease with a high incidence that is regularly accompanied by cardiovascular complications. Several studies have suggested that renin–angiotensin–aldosterone system (RAAS) is closely associated with RA.
Zhongjie Wang +9 more
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An ultrasensitive sorting mechanism for EGF receptor endocytosis [PDF]
, 2008 Background The EGF receptor has been shown to internalize via clathrin-independent endocytosis (CIE) in a ligand concentration dependent manner. From a modeling point of view, this resembles an ultrasensitive response, which is the ability of signaling ...
Roland Eils +9 more
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Atypical signaling and functional desensitization response of MAS receptor to peptide ligands. [PDF]
PLoS ONE, 2014 MAS is a G protein-coupled receptor (GPCR) implicated in multiple physiological processes. Several physiological peptide ligands such as angiotensin-(1-7), angiotensin fragments and neuropeptide FF (NPFF) are reported to act on MAS.
Kalyan C Tirupula +3 more
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Participation of Gαi-Adenylate Cyclase and ERK1/2 in Mas Receptor Signaling Pathways
Frontiers in Pharmacology, 2019 The MasR receptor (MasR) is an orphan G protein-coupled receptor proposed as a candidate for mediating the angiotensin (Ang)-converting enzyme 2-Ang-(1–7) protective axis of renin-angiotensin system.
Valeria Burghi +8 more
doaj +1 more source
Saudi Pharmaceutical Journal, 2021 Tourniquet is a well-established model of hind limb ischemia–reperfusion (HLI/R) in rats. Nevertheless, measures should be taken to alleviate the expected injury from ischemia/ reperfusion (I/R).
Azza S. Awad +2 more
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Dimerization of AT2 and Mas Receptors in Control of Blood Pressure
Current Hypertension Reports, 2018 Angiotensin type 2 receptor (AT2R) and receptor Mas (MasR) are part of the "protective arm" of the renin angiotensin system. Gene and pharmacological manipulation studies reveal that AT2R and MasR are involved in natriuretic, vasodilatory, and anti-inflammatory responses and in lowering blood pressure in various animal models under normal and ...
Sanket, Patel, Tahir, Hussain
openaire +3 more sources
An ACE2/Mas-related receptor MrgE axis in dopaminergic neuron mitochondria
Redox Biology, 2021 ACE2 plays a pivotal role in the balance between the pro-oxidative pro-inflammatory and the anti-oxidative anti-inflammatory arms of the renin-angiotensin system. Furthermore, ACE2 is the entry receptor for SARS-CoV-2.
Rita Valenzuela +9 more
doaj +1 more source
Characterization and significance of ACE2 and Mas receptor in human colon adenocarcinoma [PDF]
Journal of the Renin-Angiotensin-Aldosterone System, 2011 Introduction: A new arm of the renin–angiotensin system (RAS) has been recently characterized; this includes angiotensin converting enzyme (ACE)2 and angiotensin (Ang)1-7, a heptapeptide acting through the Mas receptor (MasR). Recent studies show that Ang1-7 has an antiproliferative action on lung adenocarcinoma cells.
BERNARDI, STELLA +12 more
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Journal of Microbiology, Immunology and Infection, 2023 Background: SARS-CoV-2 spike proteins (SP) can bind to the human angiotensin-converting enzyme 2 (ACE2) in human pulmonary alveolar epithelial cells (HPAEpiC) and trigger an inflammatory process.
Yi-Luen Shen +9 more
doaj +1 more source
Correction to: Dimerization of AT2 and Mas Receptors in Control of Blood Pressure [PDF]
Current Hypertension Reports, 2018 In the original publication, the Fig. 1 caption contains an error. The original article has been corrected.
Sanket, Patel, Tahir, Hussain
openaire +2 more sources