Results 41 to 50 of about 2,253,320 (251)

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Counter-regulatory RAS peptides: new therapy targets for inflammation and fibrotic diseases?

Frontiers in Pharmacology
The renin-angiotensin system (RAS) is an important cascade of enzymes and peptides that regulates blood pressure, volume, and electrolytes. Within this complex system of reactions, its counter-regulatory axis has attracted attention, which has been ...
Diana V. Ávila-Martínez, Diana V. Ávila-Martínez, Wendy K. Mixtega-Ruiz, Wendy K. Mixtega-Ruiz, José M. Hurtado-Capetillo, Oscar Lopez-Franco, Oscar Lopez-Franco, Mónica Flores-Muñoz, Mónica Flores-Muñoz   +8 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Mas‐Related G Protein‐Coupled Receptor Member D Sustains Hypertension

MedComm
Hypertension and its associated complications, including vascular remodeling, pose a major burden on global public health. However, the role of Mas‐related G protein‐coupled receptor member D (MrgD) in hypertension remains incompletely understood.
Kun Zhao, Dongxu Hua, Yukang Mao, Xiaoguang Wu, Min Gao, Shidong Song, Lei Chen, Xiangxiang Zheng, Peng Li   +8 more
doaj   +1 more source

Modulation of ACE2/Ang1-7/Mas and ACE/AngII/AT1 axes affects anticancer properties of sertraline in MCF-7 breast cancer cells

Biochemistry and Biophysics Reports
The renin–angiotensin system (RAS) is best known for playing a major role in maintaining the physiology of the cardiovascular system. Dysregulation of the RAS pathway has been proposed as a link to some malignancies and contributes to cancer metastasis ...
Reihaneh Fatehi, Mohammad Nouraei, Morteza Panahiyan, Marzieh Rashedinia, Negar Firouzabadi   +4 more
doaj   +1 more source

Mas‐related G protein‐coupled receptor type D antagonism improves portal hypertension in cirrhotic rats

Hepatology Communications, 2022
Splanchnic vasodilatation contributes to the development and aggravation of portal hypertension (PHT). We previously demonstrated that in cirrhosis, angiotensin‐ mediates splanchnic vasodilatation through the Mas receptor (MasR).
Lakmie S. Gunarathne, Indu G. Rajapaksha, Stephen Casey, Tawar Qaradakhi, Anthony Zulli, Harinda Rajapaksha, Jonel Trebicka, Peter W. Angus, Chandana B. Herath   +8 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Plasma and cardiac Ang 1–7 and cardiac mas receptor.

, 2013
Plasma Ang 1–7, cardiac Ang 1–7 and mas receptor expression were determined in left ventricles of sham-operated and oophorectomized female mRen2.Lewis rats treated with vehicle or estradiol for 4 weeks.
Marina Lin (476967), Leanne Groban (360082), Zhuo Zhao (476965), Jaqueline Da Silva (476966), Jewell A. Jessup (360080), Mark C. Chappell (337543), Lindsay M. MacNamara (476968), Sarfaraz Ahmad (154725), Carlos M. Ferrario (154728), Hao Wang (39217)   +9 more
core   +1 more source

Angiotensin-(1–7) Mas-receptor deficiency decreases peroxisome proliferator-activated receptor gamma expression in adipocytes [PDF]

, 2012
The renin–angiotensin system is an important link between metabolic syndrome and cardiovascular diseases. Besides angiotensin II, other angiotensin peptides such as angiotensin-(1–7), have important biological activities.
Bader, Michael, Leida Maria Botion, Botion, Leida Maria, Robson Augusto S. Santos, Érica Guilhen Mario, Michael Bader, Ferreira, Adaliene Versiane M., Adaliene Versiane M. Ferreira, Sérgio Henrique S. Santos, Mario, Érica Guilhen, Santos, Sérgio Henrique S., Santos, Robson Augusto S.   +11 more
core   +2 more sources

Sex and salt intake dependent renin-angiotensin plasticity in the liver of the rat

Endocrine Regulations, 2019
Objective. Epidemiological studies confirm that hypertensive patients respond differently to renin-angiotensin system (RAS) inhibition depending on their gender.
Pidikova Paulina, Svitok Pavel, Herichova Iveta   +2 more
doaj   +1 more source