Results 41 to 50 of about 45,545 (290)

Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla

, 2010
AIMS: Angiotensin(1-7) (Ang1-7) acting at the level of the rostral ventrolateral medulla (RVLM) affects arterial pressure. The cellular substrate of Ang1-7 remains unknown.
Tang, F, Fang Guo, Feige Tang, Samantha Lane, Souslova, E A, Ekaterina A. Souslova, Paton, JFR, Lane, S, Sergey Kasparov, Dmitriy M. Chudakov, Kasparov, S, Guo, F, Chudakov, D M, Liu, B, Beihui Liu, Julian F.R. Paton   +15 more
core   +1 more source

Angiotensin-(1-7) Mas-receptor deficiency decreases peroxisome proliferator-activated receptor gamma expression in adipocytes

, 2012
The renin-angiotensin system is an important link between metabolic syndrome and cardiovascular diseases. Besides angiotensin II, other angiotensin peptides such as angiotensin-(1-7), have important biological activities.
Ferreira, A.V.M., Botion, L.M., Mario, E.G., Santos, S.H.S., Santos, R.A.S., Bader, M.   +5 more
core   +2 more sources

Lisinopril prevents bullous pemphigoid induced by dipeptidyl peptidase 4 inhibitors via the Mas receptor pathway

Frontiers in Immunology, 2023
Recent studies have suggested that dipeptidyl peptidase 4 (DPP4) inhibitors increase the risk of development of bullous pemphigoid (BP), which is the most common autoimmune blistering skin disease; however, the associated mechanisms remain unclear, and ...
Keisuke Nozawa, Keisuke Nozawa, Takahide Suzuki, Gen Kayanuma, Hiroki Yamamoto, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko   +7 more
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

The Mas Receptor as a Future Perspective in Parkinson's Disease [PDF]

Journal of Neurology & Neuromedicine, 2018
تلقي المراجعة الحالية الضوء على أهمية نظام أنجيوتنسين الرينين الدماغي (RAS) في مرض باركنسون (PD)، كاضطراب تنكسي عصبي. تم تحديد RAS الموضعي في المسار الأسود المخطط ويلعب دورًا محوريًا في تطور مرض باركنسون عن طريق الارتباط بمستقبل أنجيوتنسين II من النوع 1 (AT -1R).
openaire   +1 more source

Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction

, 2009
IL (interleukin)-4 and IL-13 are key cytokines in the pathogenesis of allergic inflammatory disease. IL-4 and IL-13 share many functional properties as a result of their utilization of a common receptor complex comprising IL-13Ralpha1 (IL-13 receptor ...
Donna E. Davies, Holgate, Stephen T, Isabelle Kirby, Ida Karin Nordgren, Tavassoli, Ali, Davies, Donna E, Holloway, John W, Andrews, Allison-Lynn, Stephen T. Holgate, Nordgren, Ida Karin, John W. Holloway, Kirby, Isabelle, Allison-Lynn Andrews, Ali Tavassoli   +13 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

G-Protein–Coupled Receptor Mas Is a Physiological Antagonist of the Angiotensin II Type 1 Receptor [PDF]

Circulation, 2005
Background— We previously identified the G-protein–coupled receptor Mas, encoded by the Mas proto-oncogene, as an endogenous receptor for the heptapeptide angiotensin-(1-7); however, the receptor is also suggested to be involved in actions of angiotensin II.
Kostenis, Evi, Milligan, Graeme, Christopoulos, Arthur, Sanchez-Ferrer, Carlos F, Heringer-Walther, Silvia, Sexton, Patrick M, Gembardt, Florian, Kellett, Elaine, Martini, Lene, Vanderheyden, Patrick, Schultheiss, Heinz-Peter, Walther, Thomas   +11 more
openaire   +3 more sources

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Plasma and cardiac Ang 1–7 and cardiac mas receptor.

, 2013
Plasma Ang 1–7, cardiac Ang 1–7 and mas receptor expression were determined in left ventricles of sham-operated and oophorectomized female mRen2.Lewis rats treated with vehicle or estradiol for 4 weeks.
Marina Lin (476967), Leanne Groban (360082), Zhuo Zhao (476965), Jaqueline Da Silva (476966), Jewell A. Jessup (360080), Mark C. Chappell (337543), Lindsay M. MacNamara (476968), Sarfaraz Ahmad (154725), Carlos M. Ferrario (154728), Hao Wang (39217)   +9 more
core   +1 more source