Results 61 to 70 of about 45,545 (290)
Biochemistry and Biophysics ReportsThe renin–angiotensin system (RAS) is best known for playing a major role in maintaining the physiology of the cardiovascular system. Dysregulation of the RAS pathway has been proposed as a link to some malignancies and contributes to cancer metastasis ...
Reihaneh Fatehi +4 more
doaj +1 more source
Sex and salt intake dependent renin-angiotensin plasticity in the liver of the rat
Endocrine Regulations, 2019 Objective. Epidemiological studies confirm that hypertensive patients respond differently to renin-angiotensin system (RAS) inhibition depending on their gender.
Pidikova Paulina +2 more
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Ecdiesteroides y su actividad farmacológica sobre el músculo esquelético
Ars Pharmaceutica, 2023 Resumen Introducción: Los ecdiesteroides presentan cualidades únicas dentro del reino vegetal y animal. Su similitud a esteroides endógenos de mamíferos les otorga actividad biológica sobre el tejido muscular esquelético.
Vicente Otero Egocheaga
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
Endothelin-1 downregulates Mas receptor expression in human cardiomyocytes
Molecular Medicine Reports, 2013 Endothelin-1 (ET-1) and the renin-angiotensin system (RAS) are involved in the pathogenesis of cardiac dysfunction. The Mas receptor is a functional binding site for angiotensin (Ang)‑(1-7), which is now considered a critical component of the RAS and exerts cardioprotective effects.
Zhiheng, Chen +6 more
openaire +3 more sources
Validation of commercial Mas receptor antibodies for utilization in Western Blotting, immunofluorescence and immunohistochemistry studies. [PDF]
PLoS ONE, 2017 Mas receptor (MasR) is a G protein-coupled receptor proposed as a candidate for mediating the angiotensin (Ang)-converting enzyme 2-Ang (1-7) protective axis of renin-angiotensin system.
Valeria Burghi +10 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Renal vascular response to angiotensin 1-7 in rats: the role of Mas receptor
Research in Pharmaceutical Sciences, 2018 Recently a cross talk between angiotensin 1-7 (Ang1-7) receptor (MasR) and angiotensin II receptors types 1 and 2 (AT1R and AT2R) has been highlighted. The effects of MasR antagonist (A779) compared to the vehicle on the renal blood flow (RBF) and renal ...
Mehdi Nematbakhsh, Azam Mansouri
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Frontiers in Pharmacology, 2020 In previous studies we have shown that oral Ang-(1–7) has a beneficial therapeutic effect on cardiometabolic disturbances present in metabolic syndrome (MetS).
Maria Andréa Barbosa +5 more
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Effect of a Selective Mas Receptor Agonist in Cerebral Ischemia In Vitro and In Vivo. [PDF]
PLoS ONE, 2015 Functional modulation of the non-AT1R arm of the renin-angiotensin system, such as via AT2R activation, is known to improve stroke outcome. However, the relevance of the Mas receptor, which along with the AT2R forms the protective arm of the renin ...
Seyoung Lee +6 more
doaj +1 more source