Results 11 to 20 of about 174,791 (258)

Gene Profiling of the Ascorbate Oxidase Family Genes under Osmotic and Cold Stress Reveals the Role of AnAO5 in Cold Adaptation in Ammopiptanthus nanus

Plants, 2023
The uplift of the Qinghai Tibet Plateau has led to a drastic change in the climate in Central Asia, from warm and rainy, to dry and less rainfall. Ammopiptanthus nanus, a rare evergreen broad-leaved shrub distributed in the temperate desert region of ...
Ming Zhu, Qi Liu, Fuyu Liu, Lamei Zheng, Jie Bing, Yijun Zhou, Fei Gao   +6 more
doaj   +1 more source

Mass Spectrometry Imaging of Biomaterials

Materials, 2023
The science related to biomaterials and tissue engineering accounts for a growing part of our knowledge. Surface modifications of biomaterials, their performance in vitro, and the interaction between them and surrounding tissues are gaining more and more attention. It is because we are interested in finding sophisticated materials that help us to treat
Paulina Kret, Anna Bodzon-Kulakowska, Anna Drabik, Joanna Ner-Kluza, Piotr Suder, Marek Smoluch   +5 more
openaire   +2 more sources

The Characterization of R2R3-MYB Genes in Ammopiptanthus nanus Uncovers That the miR858-AnaMYB87 Module Mediates the Accumulation of Anthocyanin under Osmotic Stress

Biomolecules, 2023
R2R3-MYB transcription factors (TFs) participate in the modulation of plant development, secondary metabolism, and responses to environmental stresses.
Batu Sumbur, Fei Gao, Qi Liu, Dandan Feng, Jie Bing, Tashi Dorjee, Xuting Li, Huigai Sun, Yijun Zhou   +8 more
doaj   +1 more source

Adaptation of the Kirkstall QV600 LLI Microfluidics System for the Study of Gastrointestinal Absorption by Mass Spectrometry Imaging and LC-MS/MS

Pharmaceutics, 2022
Absorption studies on oral drugs can be difficult due to the challenge of replicating the complex structure and environment of the GI tract. Drug absorption studies can be conducted using in vivo and ex vivo animal tissue or animal-free techniques. These
Chloe E. Spencer, Stephen Rumbelow, Steve Mellor, Catherine J. Duckett, Malcolm R. Clench   +4 more
doaj   +1 more source

Imaging Mass Spectrometry

YAKUGAKU ZASSHI, 2012
Matrix-assisted laser desorption/ionization (MALDI)-imaging mass spectrometry (IMS) enables the visualization of the distribution of a range of biomolecules that have varied structures in the cells and tissue sections. This emerging imaging technique was initially developed as a tool for protein imaging, but recently it is increasingly being used for ...
Kamlesh Shrivas, Mitsutoshi Setou
openaire   +4 more sources

Multi-Modal Mass Spectrometric Imaging of Uveal Melanoma

Metabolites, 2021
Matrix assisted laser desorption ionisation mass spectrometry imaging (MALDI-MSI), was used to obtain images of lipids and metabolite distribution in formalin fixed and embedded in paraffin (FFPE) whole eye sections containing primary uveal melanomas (UM)
Laura M. Cole, Joshua Handley, Emmanuelle Claude, Catherine J. Duckett, Hardeep S. Mudhar, Karen Sisley, Malcolm R. Clench   +6 more
doaj   +1 more source

Mass Spectrometry Imaging

Mass Spectrometry, 2022
Mass spectrometry imaging (MSI) is a technique for obtaining information on the distribution of various molecules by performing mass spectrometry directly on the sample surface. The applications range from small molecules such as lipids to large molecules such as proteins.
openaire   +3 more sources

Mass spectrometry imaging identifies altered hepatic lipid signatures during experimental Leishmania donovani infection

Frontiers in Immunology, 2022
IntroductionSpatial analysis of lipids in inflammatory microenvironments is key to understand the pathogenesis of infectious disease. Granulomatous inflammation is a hallmark of leishmaniasis and changes in host and parasite lipid metabolism have been ...
Roel Tans, Shoumit Dey, Nidhi Sharma Dey, Jian-Hua Cao, Prasanjit S. Paul, Grant Calder, Peter O’Toole, Paul M. Kaye, Ron M. A. Heeren   +8 more
doaj   +1 more source

A Mass Spectrometry Primer for Mass Spectrometry Imaging [PDF]

, 2010
Mass spectrometry imaging (MSI), a rapidly growing subfield of chemical imaging, employs mass spectrometry (MS) technologies to create single- and multi-dimensional localization maps for a variety of atoms and molecules. Complimentary to other imaging approaches, MSI provides high chemical specificity and broad analyte coverage.
Stanislav S, Rubakhin, Jonathan V, Sweedler   +1 more
openaire   +2 more sources

Multiomic Mass Spectrometry Imaging to Advance Future Pathological Understanding of Ocular Disease

Metabolites, 2022
Determining the locations of proteins within the eye thought to be involved in ocular pathogenesis is important to determine how best to target them for therapeutic benefits. However, immunohistochemistry is limited by the availability and specificity of
Joshua Millar, Ema Ozaki, Susan Campbell, Catherine Duckett, Sarah Doyle, Laura M. Cole   +5 more
doaj   +1 more source