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Mass Spectrometry Imaging

Mass Spectrometry, 2022
Mass spectrometry imaging (MSI) is a technique for obtaining information on the distribution of various molecules by performing mass spectrometry directly on the sample surface. The applications range from small molecules such as lipids to large molecules such as proteins.
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Mass spectrometry imaging identifies altered hepatic lipid signatures during experimental Leishmania donovani infection

Frontiers in Immunology, 2022
IntroductionSpatial analysis of lipids in inflammatory microenvironments is key to understand the pathogenesis of infectious disease. Granulomatous inflammation is a hallmark of leishmaniasis and changes in host and parasite lipid metabolism have been ...
Roel Tans, Shoumit Dey, Nidhi Sharma Dey, Jian-Hua Cao, Prasanjit S. Paul, Grant Calder, Peter O’Toole, Paul M. Kaye, Ron M. A. Heeren   +8 more
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A Mass Spectrometry Primer for Mass Spectrometry Imaging [PDF]

, 2010
Mass spectrometry imaging (MSI), a rapidly growing subfield of chemical imaging, employs mass spectrometry (MS) technologies to create single- and multi-dimensional localization maps for a variety of atoms and molecules. Complimentary to other imaging approaches, MSI provides high chemical specificity and broad analyte coverage.
Stanislav S, Rubakhin, Jonathan V, Sweedler   +1 more
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TOF-SIMS Imaging of Biological Tissue Sections and Structural Determination Using Tandem MS

, 2022
Over the past couple of years, imaging mass spectrometry (IMS) has arisen as a powerful tool to answer research questions in the biomedical field. Imaging mass spectrometry allows for label-free chemical imaging by providing full molecular information ...
Brunelle, Alain, Lee, Y.J., Van Nuffel, Sebastiaan   +2 more
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Mass Spectrometry Imaging of Drug Related Crystal-Like Structures in Formalin-Fixed Frozen and Paraffin-Embedded Rabbit Kidney Tissue Sections [PDF]

, 2015
A multimodal mass spectrometry imaging (MSI) based approach was used to characterize the molecular content of crystal-like structures in a frozen and paraffin embedded piece of a formalin-fixed rabbit kidney.
Heerden, M. (Marjolein) van, Cuyckens, Filip, Heeren, Ron M. A., Cuyckens, F., Eijkel, Gert B., Heeren, R.M.A. (Ron), Oevelen, Cateau van, Eijkel, G.B. (Gert), Bruinen, A.L., Van Heerden, Marjolein, van Oevelen, Cateau, Bruinen, Anne L.   +11 more
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Towards a model for road runoff infiltration management

npj Clean Water, 2021
In human society, there is a demand for sustainable solutions for water preservation and efficient treatment systems. An important water reservoir is road runoff defined as rainwater leaching from roads, loading micropollutants and infiltrating the soil.
Loïc Maurer, Julie Zumsteg, Carole Lutz, Marie Pierre Ottermatte, Adrien Wanko, Dimitri Heintz, Claire Villette   +6 more
doaj   +1 more source

Multiomic Mass Spectrometry Imaging to Advance Future Pathological Understanding of Ocular Disease

Metabolites, 2022
Determining the locations of proteins within the eye thought to be involved in ocular pathogenesis is important to determine how best to target them for therapeutic benefits. However, immunohistochemistry is limited by the availability and specificity of
Joshua Millar, Ema Ozaki, Susan Campbell, Catherine Duckett, Sarah Doyle, Laura M. Cole   +5 more
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Prognostic Metabolite Biomarkers for Soft Tissue Sarcomas Discovered by Mass Spectrometry Imaging [PDF]

, 2017
Metabolites can be an important read-out of disease. The identification and validation of biomarkers in the cancer metabolome that can stratify high-risk patients is one of the main current research aspects.
Bovee, J.V.M.G., McDonnell, L.A., Lou, Sha, Lou, S., Cleven, Arjen H. G., Cleven, A.H.G., Balluff, B., Judith V. M. G. Bovée, Bovee, Judith V. M. G., Benjamin Balluff, Liam A. McDonnell, Sha Lou, Balluff, Benjamin, McDonnell, Liam A., Arjen H. G. Cleven   +14 more
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Ion Imaging of Native Protein Complexes Using Orthogonal Time-of-Flight Mass Spectrometry and a Timepix Detector [PDF]

, 2021
Native mass spectrometry (native MS) has emerged as a powerful technique to study the structure and stoichiometry of large protein complexes. Traditionally, native MS has been performed on modified time-of-flight (TOF) systems combined with detectors ...
Heck, A.J.R. (Albert), Heck, A.J.R., Heeren, Ron M A, Spaanderman, D.-J. (Dirk-Jan), Spaanderman, Dirk-Jan, Byelov, D. (Dimitry), Mathew, A., Dyachenko, Andrey, Porta Siegel, Tiffany, Dyachenko, A., Mathew, Anjusha, Spaanderman, D.J., Buijs, R. (Ronald), Heeren, R.M.A. (Ron), Byelov, D., Mathew, A. (Anjusha), van der Horst, J., Heck, Albert J R, Heeren, R.M.A., Siegel, T.P. (Tiffany Porta), Giskes, F.G. (Frans), Buijs, R., Eijkel, Gert B, Ellis, Shane R, Eijkel, G.B. (Gert), Dyachenko, A. (Andrey), Giskes, F., Eijkel, G.B., Siegel, T.P., Giskes, Frans, Horst, J. (Jerre) van der, Ellis, S.R. (Shane), Byelov, Dimitry, van der Horst, Jerre, Ellis, S.R., Buijs, Ronald, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics, Afd Biomol.Mass Spect. and Proteomics, Dimitry Byelov, Dirk-Jan Spaanderman, Anjusha Mathew, Ronald Buijs, Ron M. A. Heeren, Jerre van der Horst, Gert B. Eijkel, Albert J. R. Heck, Frans Giskes, Tiffany Porta Siegel, Shane R. Ellis, Andrey Dyachenko   +50 more
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Single Particle Mass Spectrometry and Inertial Imaging with Nanomechanical Systems [PDF]

, 2013
This thesis work describes the development of a new technology for mass spectrometry using nanoelectromechanical systems (NEMS-MS). Mass spectrometry is a technique used to identify molecules through mass measurement.
Kelber, Scott Ian
core   +1 more source