Journal of Spectral Imaging, 2019 Matrix-Assisted Ionisation in Vacuum (MAIV) is a new ionisation technique which ionises non-volatile compounds producing electrospray ionisation-like spectra.
Alex James Harding +4 more
doaj +1 more source
Scientific Reports, 2021 Frozen section analysis is a frequently used method for examination of tissue samples, especially for tumour detection. In the majority of cases, the aim is to identify characteristic tissue morphologies or tumour margins. Depending on the type of tissue,
Tim Kümmel +8 more
doaj +1 more source
Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level. [PDF]
, 2018 ‘A picture is worth a thousand words’ is an idiom from the English language (‘borrowed’ from on old Chinese proverb) that conveys the notion that a complex idea can be succinctly and fully described by a single image. Never has this expression been truer
Andrén, PE +11 more
core +3 more sources
Mass spectrometry imaging identifies palmitoylcarnitine as an immunological mediator during Salmonella Typhimurium infection [PDF]
, 2017 Salmonella Typhimurium causes a self-limiting gastroenteritis that may lead to systemic disease. Bacteria invade the small intestine, crossing the intestinal epithelium from where they are transported to the mesenteric lymph nodes (MLNs) within migrating
A Perez-Lopez +57 more
core +1 more source
Emerging technologies in mass spectrometry imaging [PDF]
Journal of Proteomics, 2012 Mass spectrometry imaging (MSI) as an analytical tool for bio-molecular and bio-medical research targets, accurate compound localization and identification. In terms of dedicated instrumentation, this translates into the demand for more detail in the image dimension (spatial resolution) and in the spectral dimension (mass resolution and accuracy ...
Jungmann, Julia H., Heeren, Ron M. A.
openaire +3 more sources
Imaging Mass Spectrometry: A Perspective [PDF]
Journal of Biomolecular Techniques : JBT, 2019 Imaging mass spectrometry (IMS) has emerged as an important imaging modality because of its broad non-specific nature for molecular detection from highly complex samples. Within this broad field, new sub-categories of technologies have been developed incorporating many different molecular ionization processes.
openaire +2 more sources
Mass spectrometry imaging of cassette-dosed drugs for higher throughput pharmacokinetic and biodistribution analysis [PDF]
, 2014 Cassette dosing of compounds for preclinical drug plasma pharmacokinetic analysis has been shown to be a powerful strategy within the pharmaceutical industry for increasing throughput while decreasing the number of animals used.
Andren, Per E. +10 more
core +1 more source
Rapid deconvolution of low-resolution time-of-flight data using Bayesian inference [PDF]
, 2019 The deconvolution of low-resolution time-of-flight data has numerous advantages, including the ability to extract additional information from the experimental data.
Bernardo J. M. +7 more
core +2 more sources
Enzymatic transhalogenation of dendritic RGD peptide constructs with the fluorinase [PDF]
, 2016 We thank EPSRC and the Scottish Imaging Network (SINAPSE) for grants. DO’H thanks the Royal Society for a Wolfson Research Merit Award and ST is grateful to the John and Kathleen Watson Scholarship for financial support.
Fleming, Ian N. +2 more
core +1 more source
Probing Coherent Vibrations of Organic Phosphonate Radical Cations with Femtosecond Time-Resolved Mass Spectrometry [PDF]
, 2019 Organic phosphates and phosphonates are present in a number of cellular components that can be damaged by exposure to ionizing radiation. This work reports femtosecond time-resolved mass spectrometry (FTRMS) studies of three organic phosphonate radical ...
Ampadu Boateng, Derrick +2 more
core +3 more sources