Results 21 to 30 of about 174,791 (258)

Imaging Mass Spectrometry in Neuroscience [PDF]

ACS Chemical Neuroscience, 2013
Imaging mass spectrometry is an emerging technique of great potential for investigating the chemical architecture in biological matrices. Although the potential for studying neurobiological systems is evident, the relevance of the technique for application in neuroscience is still in its infancy.
Jörg Hanrieder, Nhu T. N. Phan, Michael E. Kurczy, Andrew G. Ewing   +3 more
openaire   +2 more sources

Towards a model for road runoff infiltration management

npj Clean Water, 2021
In human society, there is a demand for sustainable solutions for water preservation and efficient treatment systems. An important water reservoir is road runoff defined as rainwater leaching from roads, loading micropollutants and infiltrating the soil.
Loïc Maurer, Julie Zumsteg, Carole Lutz, Marie Pierre Ottermatte, Adrien Wanko, Dimitri Heintz, Claire Villette   +6 more
doaj   +1 more source

Imaging mass spectrometry: Hype or hope? [PDF]

Journal of the American Society for Mass Spectrometry, 2009
Imaging mass spectrometry is currently receiving a significant amount of attention in the mass spectrometric community. It offers the potential of direct examination of biomolecular patterns from cells and tissue. This makes it a seemingly ideal tool for biomedical diagnostics and molecular histology.
R.M.A. Heeren (Ron), D.F. Smith (Donald), J. Stauber, B. Kükrer-Kaletas, L. MacAleese (Luke)   +4 more
openaire   +4 more sources

Mass spectrometry imaging for biosolids characterization to assess ecological or health risks before reuse

Nature Communications, 2023
Biosolids are byproducts of wastewater treatment. With the increasing global population, the amounts of wastewater to be treated are expanding, along with the amounts of biosolids generated.
Claire Villette, Loïc Maurer, Julie Zumsteg, Jérôme Mutterer, Adrien Wanko, Dimitri Heintz   +5 more
doaj   +1 more source

Lipid Analysis of Fracture Hematoma With MALDI-MSI: Specific Lipids are Associated to Bone Fracture Healing Over Time

Frontiers in Chemistry, 2022
Background: Fracture healing is a complex process, involving cell-cell interactions, various cytokines, and growth factors. Although fracture treatment improved over the last decades, a substantial part of all fractures shows delayed or absent healing ...
Rald V. M. Groven, Rald V. M. Groven, Sylvia P. Nauta, Sylvia P. Nauta, Jane Gruisen, Jane Gruisen, Britt S. R. Claes, Johannes Greven, Martijn van Griensven, Martijn Poeze, Martijn Poeze, Ron M. A. Heeren, Tiffany Porta Siegel, Berta Cillero-Pastor, Taco J. Blokhuis, Taco J. Blokhuis   +15 more
doaj   +1 more source

Matrix-assisted ionisation in vacuum mass spectrometry and imaging on a modified quadrupole-quadrupole-time-of-flight mass spectrometer

Journal of Spectral Imaging, 2019
Matrix-Assisted Ionisation in Vacuum (MAIV) is a new ionisation technique which ionises non-volatile compounds producing electrospray ionisation-like spectra.
Alex James Harding, James Hough, Charlotte Curtis, Daniel Kinsman, Malcolm R. Clench   +4 more
doaj   +1 more source

Emerging technologies in mass spectrometry imaging [PDF]

Journal of Proteomics, 2012
Mass spectrometry imaging (MSI) as an analytical tool for bio-molecular and bio-medical research targets, accurate compound localization and identification. In terms of dedicated instrumentation, this translates into the demand for more detail in the image dimension (spatial resolution) and in the spectral dimension (mass resolution and accuracy ...
Jungmann, Julia H., Heeren, Ron M. A.
openaire   +3 more sources

Rapid brain structure and tumour margin detection on whole frozen tissue sections by fast multiphotometric mid-infrared scanning

Scientific Reports, 2021
Frozen section analysis is a frequently used method for examination of tissue samples, especially for tumour detection. In the majority of cases, the aim is to identify characteristic tissue morphologies or tumour margins. Depending on the type of tissue,
Tim Kümmel, Björn van Marwick, Miriam Rittel, Carina Ramallo Guevara, Felix Wühler, Tobias Teumer, Björn Wängler, Carsten Hopf, Matthias Rädle   +8 more
doaj   +1 more source

Imaging Mass Spectrometry: A Perspective [PDF]

Journal of Biomolecular Techniques : JBT, 2019
Imaging mass spectrometry (IMS) has emerged as an important imaging modality because of its broad non-specific nature for molecular detection from highly complex samples. Within this broad field, new sub-categories of technologies have been developed incorporating many different molecular ionization processes.
openaire   +2 more sources

Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents

Nature Communications, 2023
Prosaposin (PSAP) modulates glycosphingolipid metabolism and variants have been linked to Parkinson’s disease (PD). Here, we find altered PSAP levels in the plasma, CSF and post-mortem brain of PD patients.
Yachao He, Ibrahim Kaya, Reza Shariatgorji, Johan Lundkvist, Lars U. Wahlberg, Anna Nilsson, Dejan Mamula, Jan Kehr, Justyna Zareba-Paslawska, Henrik Biverstål, Karima Chergui, Xiaoqun Zhang, Per E. Andren, Per Svenningsson   +13 more
doaj   +1 more source