Results 71 to 80 of about 5,293,958 (301)

On the importance of color in mass spectrometry imaging

open access: yesJournal of Mass Spectrometry, 2022
AbstractMass spectrometry imaging (MSI) data visualization relies on heatmaps to show the spatial distribution and measured abundances of molecules within a sample. Nonuniform color gradients such as jet are still commonly used to visualize MSI data, increasing the probability of data misinterpretation and false conclusions. Also, the use of nonuniform
Kevan T. Knizner   +5 more
openaire   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Chemical and Transcriptomic Analyses of Leaf Cuticular Wax Metabolism in Ammopiptanthus mongolicus under Osmotic Stress

open access: yesBiomolecules
Plant cuticular wax forms a hydrophobic structure in the cuticle layer covering epidermis as the first barrier between plants and environments. Ammopiptanthus mongolicus, a leguminous desert shrub, exhibits high tolerances to multiple abiotic stress. The
Batu Sumbur   +7 more
doaj   +1 more source

Both age and social environment shape the phenotype of ant workers

open access: yesScientific Reports, 2023
Position within the social group has consequences on individual lifespans in diverse taxa. This is especially obvious in eusocial insects, where workers differ in both the tasks they perform and their aging rates.
Martin Quque   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

The Application of Mass Spectrometry in Molecular Dosimetry: Ethylene Oxide as an Example

open access: yes, 2012
Mass spectrometry plays an increasingly important role in the search for and quantification of novel chemically specific biomarkers. The revolutionary advances in mass spectrometry instrumentation and technology empower scientists to specifically analyze
WU, KUEN-YUH;CHIANG, SU-YIN;SHIH, WEI-CHUNG;HUANG, CHIH-CHUN JEAN;CHEN, MING-FENG   +1 more
core   +1 more source

Spatially Resolved Immunometabolism to Understand Infectious Disease Progression

open access: yesFrontiers in Microbiology, 2021
Infectious diseases, including those of viral, bacterial, fungal, and parasitic origin are often characterized by focal inflammation occurring in one or more distinct tissues.
Roel Tans   +6 more
doaj   +1 more source

Mass spectrometry imaging 2.0 [PDF]

open access: yesAnalytical and Bioanalytical Chemistry, 2021
Tiffany Porta Siegel, Shane R. Ellis
openaire   +3 more sources

Mass Spectrometry Imaging for Glycome in the Brain

open access: yesFrontiers in Neuroanatomy, 2021
Glycans are diverse structured biomolecules that play crucial roles in various biological processes. Glycosylation, an enzymatic system through which various glycans are bound to proteins and lipids, is the most common and functionally crucial post-translational modification process.
Md. Mahmudul Hasan   +11 more
openaire   +3 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy