We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan +9 more
wiley +1 more source
Spatial Phenotype of the Mast Cell Population in Endometritis of Various Severities. [PDF]
Mikhalev S +14 more
europepmc +1 more source
Current state of biology and diagnosis of clonal mast cell diseases in adults [PDF]
Iván Álvarez‐Twöse +6 more
openalex +1 more source
Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv +5 more
wiley +1 more source
Modulation of Mast Cell Activation via MRGPRX2 by Natural Oat Extract. [PDF]
Kaesler S +14 more
europepmc +1 more source
A Detailed Mathematical Model Predicts That Serial Engagement of IgE–FcεRI Complexes Can Enhance Syk Activation in Mast Cells [PDF]
Ambarish Nag +3 more
openalex +1 more source
Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq +2 more
wiley +1 more source
IL-33-mediated mast cell and eosinophil function requires isoprenylation. [PDF]
Burchett JR +11 more
europepmc +1 more source
CellOntologyMapper: Consensus mapping of cell type annotation
CellOntologyMapper automates the standardization of cell type annotations in single‐cell RNA‐seq by mapping user‐defined names to the Cell Ontology (CL) and Cell Taxonomy (CT). The framework constructs a comprehensive embedding database of 19,381 curated cell types using sentence transformers, large language models, and synonym expansion.
Zehua Zeng +3 more
wiley +1 more source
Expanding the Diagnostic Lens: Mast Cell Activation Syndromes and the Hidden Spectrum of Angioedema Associated Mortality in COVID-19. [PDF]
Sison EL, Aban JL.
europepmc +2 more sources

