Results 191 to 200 of about 12,201,289 (252)

Human Mast Cell Proteome Reveals Unique Lineage, Putative Functions, and Structural Basis for Cell Ablation

open access: yesImmunity, 2020
Mast cells are rare tissue-resident cells of importance to human allergies. To understand the structural basis of principle mast cell functions, we analyzed the proteome of primary human and mouse mast cells by quantitative mass spectrometry.
Thomas Plum, Xi Wang, Mandy Rettel
exaly   +2 more sources
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Mast cell progenitors: Origin, development and migration to tissues

open access: yesMolecular Immunology, 2015
Mast cells in tissues are developed from mast cell progenitors emerging from the bone marrow in a process highly regulated by transcription factors. Through the advancement of the multicolor flow cytometry technique, the mast cell progenitor population ...
Joakim S Dahlin, Jenny Hallgren
exaly   +2 more sources

Mast cell secretory granules: armed for battle

Nature Reviews Immunology, 2014
Sara Wernersson   +2 more
exaly   +2 more sources

Mast cells

Physiological Reviews, 1997
Mast cells are found resident in tissues throughout the body, particularly in association with structures such as blood vessels and nerves, and in proximity to surfaces that interface the external environment. Mast cells are bone marrow-derived and particularly depend upon stem cell factor for their survival. Mast cells express a variety of phenotypic
van Loveren, H   +5 more
openaire   +5 more sources

TH9 cells are required for tissue mast cell accumulation during allergic inflammation

open access: yesJournal of Allergy and Clinical Immunology, 2015
Background IL-9 is important for the growth and survival of mast cells. IL-9 is produced by T cells, NKT cells, mast cells, eosinophils, and innate lymphoid cells, although the cells required for mast cell accumulation during allergic inflammation remain
Sarita Sehra   +2 more
exaly   +2 more sources

Mast cell-orchestrated immunity to pathogens

open access: yesNature Reviews Immunology, 2010
Although mast cells were discovered more than a century ago, their functions beyond their role in allergic responses remained elusive until recently. However, there is a growing appreciation that an important physiological function of these cells is the ...
Soman N Abraham   +2 more
exaly   +2 more sources

Is a mast cell a mast cell a mast cell?

Journal of Allergy and Clinical Immunology, 1980
The readers of this JOURNAL are all aware that increases in cyclic adenosine monophosphate (cyclic AMP) in mast cells and basophilic leukocytes in vitro are associated with suppression of the immunologically induced release of mediators. The drugs that are the mainstays of therapy in treating bronchial asthma are, for the most part, capable of ...
openaire   +2 more sources

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