Results 201 to 210 of about 5,434,736 (260)

Mast cell-driven remodeling of pulmonary immune and stromal landscapes in COVID-19. [PDF]

open access: yesSci Rep
Atiakshin DA   +13 more
europepmc   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri   +5 more
wiley   +1 more source

The evaluation of boundary‐layer turbulence in high‐resolution numerical weather prediction simulations using Doppler lidar

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
A new method compares both kilometer and sub‐kilometre weather model simulations with Doppler lidar observations to assess the representation of boundary‐layer turbulence. While bulk boundary‐layer properties are well represented, vertical velocity variance is strongly underestimated in both simulations.
Natalie J. Harvey   +7 more
wiley   +1 more source

Progressive emergence of canopy gravity waves during the afternoon–evening transition

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
Large‐eddy simulations are used to investigate the afternoon‐to‐evening transition of turbulence over a forest canopy and its coupling with atmospheric boundary‐layer dynamics. As surface cooling strengthens stability and weakens near‐canopy winds, canopy turbulence transitions progressively to internal gravity waves that dominate the evening flow ...
S. Dupont
wiley   +1 more source

Mast cell proteases and their significance in physiology, pathology, and therapeutic approaches. [PDF]

open access: yesPharmacol Rev
Derakhshani A   +9 more
europepmc   +1 more source

Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation

open access: yesRespirology, EarlyView.
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley   +1 more source

Systemic inflammation increases mast cell numbers in coronary arteries in patients who died from myocardial infarction. [PDF]

open access: yesJ Mol Cell Cardiol Plus
Fiet MD   +10 more
europepmc   +1 more source

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