Results 221 to 230 of about 172,226 (310)

Spatial Phenotype of the Mast Cell Population in Endometritis of Various Severities. [PDF]

Cells
Mikhalev S, Kostin A, Kurtser M, Radzinsky V, Orazov M, Alekhnovich A, Prikhodko A, Demyashkin G, Klabukov I, Baranovskii D, Elieh-Ali-Komi D, Buchwalow I, Tiemann M, Mikhaleva L, Atiakshin D.   +14 more
europepmc   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Mast Cell Chymase and Human Lung Fibroblast Interaction: Mechanisms and Implications for Asthma. [PDF]

Inflammation
Pejler G, Paivandy A, Rabelo Melo F, Allam VSRR, Öberg A, Wen Q, Bergsten P, Zhao XO.   +7 more
europepmc   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation. [PDF]

Cell Rep
Nagai J, Hastings MM, Nishida A, Majumdar S, Zaleski K, Marshall SA, Lin J, Saliman MAS, Tani Y, Murakami Y, Feng C, Perniss A, Wong C, Bankova LG, Inoue A, Barrett NA, Boyce JA.   +16 more
europepmc   +1 more source

The evaluation of boundary‐layer turbulence in high‐resolution numerical weather prediction simulations using Doppler lidar

Quarterly Journal of the Royal Meteorological Society, EarlyView.
A new method compares both kilometer and sub‐kilometre weather model simulations with Doppler lidar observations to assess the representation of boundary‐layer turbulence. While bulk boundary‐layer properties are well represented, vertical velocity variance is strongly underestimated in both simulations.
Natalie J. Harvey, Helen F. Dacre, Kirsty E. Hanley, Humphrey W. Lean, Christopher J. Walden, Michael Baidu, Steven Boeing, Andrew N. Ross   +7 more
wiley   +1 more source

PBX3 regulates mast cell parthanatos via TOP2A mediated DNA damage in allergic rhinitis. [PDF]

iScience
Wu S, Zhu X, Xie W, Liu J, Li C, Wang M, Peng H.   +6 more
europepmc   +1 more source

Impact of sleep insufficiency and recovery on cancer development

Sleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Mast cell-derived MIF Polarizes Th17 cells to drive lung adenocarcinoma progression. [PDF]

Cancer Immunol Immunother
Peng Q, Ye X, Xu X, Song J, Yang Z, Xiao H.   +5 more
europepmc   +1 more source

Deepening the real options debate: Real options as dynamic optimization

Strategic Management Journal, EarlyView.
Abstract Research Summary Is real option theory useful for management research? This topic was hotly debated two decades ago. Real options were said to be inapplicable to management research and to lack conceptual distinctiveness. Whereas responses to the claim about the non‐distinctiveness of real options were disparate, the concern about the theory's
Arkadiy V. Sakhartov, Joseph T. Mahoney, Jeffrey J. Reuer   +2 more
wiley   +1 more source