Results 241 to 250 of about 172,226 (310)

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source

IL-33-mediated mast cell and eosinophil function requires isoprenylation. [PDF]

Front Immunol
Burchett JR, Kotha A, Davis DT, Jackson KG, Dailey JM, Maldonado TD, Haque TT, Hussain ZY, Ching JM, Frischmeyer-Guerrerio P, Sebti SM, Ryan JJ.   +11 more
europepmc   +1 more source

Angiogenesis‐associated immune genes as prognostic markers and predictors of immunotherapy response in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang, Qian Wang, Xiumei Jiang, Yongmei Yang, Ailin Qu   +4 more
wiley   +1 more source

Sinus mast cell accumulation and persistence suggest a unique endotype in toxin exposure-associated chronic rhinosinusitis. [PDF]

J Clin Invest
Wang X, Huang YA, Sethi A, Yue C, Brack S, Chattuparambil Binoy A, Crowther L, Yan C, Deconde A, Kushnaryov A, Vahabzadeh-Hagh A, Husseman J, Little M, Strohm A, Jih L, Lyons JJ, Broide DH, Doherty TA.   +17 more
europepmc   +1 more source

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source

Hypokalemic Periodic Paralysis in a Young Woman With Mast Cell Activation Syndrome: A Case Report of an Atypical Presentation Associated With an Ultra-Rare CACNA1S Variant. [PDF]

Clin Case Rep
Moradi A, Aboutaleb Y, Noreen S, Sahyouni A, Sharma H, Oyesanmi O, Kahane IM, Lin Y, Toka HR.   +8 more
europepmc   +1 more source

Mast cell-expressed Mrgprb2/MRGPRX2 mediates gout pain and inflammation via a neuroimmune axis. [PDF]

JCI Insight
Yang L, Liu C, Xiao J, Song Y, Chen H, Li D, Zou C, Hong T, Liu Y, Qi D, Limjunyawong N, Liu W, Qu L.   +12 more
europepmc   +1 more source

Early Intervention With Biologics for Asthma Remission: Promising or Premature?

Respirology, EarlyView.
Santi Nolasco, Jaime Bernaola, Parameswaran Nair   +2 more
wiley   +1 more source