Results 211 to 220 of about 12,201,289 (252)
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American Journal of Clinical Pathology, 1975
Autopsy of a patient with well-documented myelofibrosis revealed marked proliferation of mast cells associated with areas of bone-marrow and splenic fibrosis. The findings suggest that the local fibrosis represents the healed phase of an inflammatory reaction mediated by mast cells via the release of histamine into the tissue spaces.
W C, Udoji, S A, Razavi
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Autopsy of a patient with well-documented myelofibrosis revealed marked proliferation of mast cells associated with areas of bone-marrow and splenic fibrosis. The findings suggest that the local fibrosis represents the healed phase of an inflammatory reaction mediated by mast cells via the release of histamine into the tissue spaces.
W C, Udoji, S A, Razavi
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Immunological Reviews, 2018
SummaryMast cells are a part of the innate immune system implicated in allergic reactions and the regulation of host‐pathogen interactions. The distribution, morphology and biochemical composition of mast cells has been studied in detail in vitro and on tissue sections both at the light microscopic and ultrastructural level.
Shweta Tikoo +6 more
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SummaryMast cells are a part of the innate immune system implicated in allergic reactions and the regulation of host‐pathogen interactions. The distribution, morphology and biochemical composition of mast cells has been studied in detail in vitro and on tissue sections both at the light microscopic and ultrastructural level.
Shweta Tikoo +6 more
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Science, 1966
Subcutaneous injections of normally well tolerated amounts of hypertonic NaCl or urea solutions produce extensive topical necroses in rats systemically treated with various mast-cell dischargers and mast-cell products. This response is considered to be closely related to mast-cell function, for it cannot be duplicated by systemic treatment with a ...
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Subcutaneous injections of normally well tolerated amounts of hypertonic NaCl or urea solutions produce extensive topical necroses in rats systemically treated with various mast-cell dischargers and mast-cell products. This response is considered to be closely related to mast-cell function, for it cannot be duplicated by systemic treatment with a ...
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Digestive Diseases, 2009
Mast cells (MCs) typically reside at barrier sites of the body, including the intestinal mucosa, and play a vital role in innate host defence. Activated MCs release a wide variety of bioactive mediators. These include preformed mediators stored in the granules (e.g. histamine and tryptase) and newly synthesised mediators (e.g.
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Mast cells (MCs) typically reside at barrier sites of the body, including the intestinal mucosa, and play a vital role in innate host defence. Activated MCs release a wide variety of bioactive mediators. These include preformed mediators stored in the granules (e.g. histamine and tryptase) and newly synthesised mediators (e.g.
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Molecular Immunology, 1982
Mast cells secrete histamine, glycosaminoglycans, arachidonic acid derivatives, enzymes, and possibly whole granules. Physiologic stimuli include the bridging of membrane-bound IgE molecules by antigen, the anaphylatoxins C5a and C3a, and the neurotransmitter acetylcholine.
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Mast cells secrete histamine, glycosaminoglycans, arachidonic acid derivatives, enzymes, and possibly whole granules. Physiologic stimuli include the bridging of membrane-bound IgE molecules by antigen, the anaphylatoxins C5a and C3a, and the neurotransmitter acetylcholine.
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2005
Apoptosis is a physiological form of cell death. Cells undergoing apoptosis execute a genetically controlled program that leads to organized breakdown of cellular structures and ends in phagocytosis of their remains. In mast cells, several mechanisms regulating apoptosis have been identified including growth factors, tumor necrosis factor-alpha ...
Alexander, Gerbaulet +2 more
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Apoptosis is a physiological form of cell death. Cells undergoing apoptosis execute a genetically controlled program that leads to organized breakdown of cellular structures and ends in phagocytosis of their remains. In mast cells, several mechanisms regulating apoptosis have been identified including growth factors, tumor necrosis factor-alpha ...
Alexander, Gerbaulet +2 more
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1963
Publisher Summary This chapter highlights the tissue mast cell. The mast cells are the ubiquitous element of the connective tissue. Carefully made whole mounts of mesentery and skin or spreads of connective tissue afford visualization of the entire mast cell and its environment.
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Publisher Summary This chapter highlights the tissue mast cell. The mast cells are the ubiquitous element of the connective tissue. Carefully made whole mounts of mesentery and skin or spreads of connective tissue afford visualization of the entire mast cell and its environment.
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Otolaryngology–Head and Neck Surgery, 1992
The precise mode of action of the well‐studied cromolyn sodium and the newer nedocromil sodium has not been completely elucidated. Because the drugs do not pass the cell membrane and enter the cell, they are virtually not metabolized, do not exert a systemic action, and therefore are associated with only minimal systemic toxicity.
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The precise mode of action of the well‐studied cromolyn sodium and the newer nedocromil sodium has not been completely elucidated. Because the drugs do not pass the cell membrane and enter the cell, they are virtually not metabolized, do not exert a systemic action, and therefore are associated with only minimal systemic toxicity.
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2018
This chapter persuades the reader that many, if not all mast cells are innervated, that is, mast cells are closely apposed to varicose axons and that the interchange of chemical messengers occurs at these sites. It demonstrates an intimate microanatomical association of the presumably bone-marrow-derived mucosal mast cell with subepithelial nerves in ...
Stead R. H. +5 more
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This chapter persuades the reader that many, if not all mast cells are innervated, that is, mast cells are closely apposed to varicose axons and that the interchange of chemical messengers occurs at these sites. It demonstrates an intimate microanatomical association of the presumably bone-marrow-derived mucosal mast cell with subepithelial nerves in ...
Stead R. H. +5 more
openaire +3 more sources