Results 171 to 180 of about 5,434,736 (260)

WTAP‐Mediated m6A Modification of TXNDC5 mRNA Promotes Cervical Carcinogenesis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT WT1‐associated protein (WTAP), a core component of the methyltransferase complex, is involved in various tumor pathological processes, but its specific mechanism in cervical cancer (CC) remains unclear. This study, based on single‐cell transcriptomic data (including 3 CC and 2 normal tissues), constructed a CC microenvironment cell atlas ...
Ling Chen   +4 more
wiley   +1 more source

Mechanism of RNA‐Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu   +2 more
wiley   +1 more source

Exploring mast cell phenotype and functions during tumor progression

open access: yes
Introduction Mast cells (MCs) infiltrate both human and mouse colorectal cancer (CRC) lesions but their role in tumor progression is still controversial.
Erisa Putro   +6 more
core  

Cutaneous mast cell tumors in dogs: Association with gonadectomy. [PDF]

open access: yesBraz J Vet Med
Sollier Podestá F   +4 more
europepmc   +1 more source

Disulfidptosis‐ and Ferroptosis‐Related Gene Signatures in Rheumatoid Arthritis: Association Analysis and Diagnostic Model Construction

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint damage. Although ferroptosis has been implicated in RA progression, the role of disulfidptosis and its interaction with ferroptosis remains unclear.
Ting‐Ting Wang   +10 more
wiley   +1 more source

Therapeutic JAK Inhibition in Idiopathic Subglottic Stenosis

open access: yesThe Laryngoscope, EarlyView.
Three patients with idiopathic subglottic stenosis and rheumatoid arthritis began JAK inhibitor therapy, after which the mean surgical‐free interval between endoscopic dilations rose from 317 to 631 days and the annualized dilation rate fell from 1.24 to 0.38 per patient‐year. Figure 2 shows this as a per‐patient timeline.
Riley M. Larkin   +5 more
wiley   +1 more source

Disseminated cutaneous mast cell tumor in a South American coati (Nasua nasua). [PDF]

open access: yesVet Res Commun
Mazaro RD   +6 more
europepmc   +1 more source

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