Efficacy and toxicity of hydroxyurea in mast cell activation syndrome patients refractory to standard medical therapy: retrospective case series. [PDF]
Naunyn Schmiedebergs Arch Pharmacol, 2022 Weinstock LB, Brook JB, Molderings GJ.
europepmc +1 more source
Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications
Immunology, EarlyView.PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang +9 more
wiley +1 more source
Removal of Polymer Clips From the Gallbladder Fossa in a Patient With Ehlers-Danlos Syndrome (EDS) to Treat Mast Cell Activation Syndrome (MCAS): A Case Report. [PDF]
Cureus, 2023 Xiao Y, Calixte DA, Fry E, Tiesenga F.
europepmc +1 more source
Immunology, EarlyView.This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann +7 more
wiley +1 more source
Management of chronic urticaria: Current status and future prospect
Journal of the European Academy of Dermatology and Venereology, EarlyView.Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman +15 more
wiley +1 more source
Safe administration of chemotherapy in mast cell activation syndrome. [PDF]
J Oncol Pharm Pract, 2021 Lythgoe MP +3 more
europepmc +1 more source
Female genital lichen sclerosus
Journal of the European Academy of Dermatology and Venereology, EarlyView.This review provides a comprehensive overview of clinical presentation and emerging evidence supporting a predominantly immune‐mediated pathogenesis characterized by Th1‐skewed inflammation, epithelial dysfunction and progressive fibrosis. Contributory factors including the emerging role for occlusive exposure of susceptible epithelium to urine are ...
Ashley Spencer, Sandra Jerkovic Gulin
wiley +1 more source
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aim Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling illness that frequently begins in adolescence, yet adolescents with ME/CFS remain an under‐researched population. We aimed to characterise the cognitive and psychosocial wellbeing of adolescents with ME/CFS relative to normative benchmarks and unaffected age‐peers ...
Tracey Chau +8 more
wiley +1 more source
Anesthetic management of mast cell activation syndrome: A journal course review [PDF]
Mast cell activation syndrome (MCAS) is a disorder that has only gained recognition in the past twelve years. Patients that are diagnosed with MCAS are plagued with abnormal acute and/or chronic mild to severe (anaphylaxis) mast cell activation (MCA ...
Glasgow, Candace
core
Mast Cell Activation Syndrome in COVID-19 and Female Reproductive Function: Theoretical Background vs. Accumulating Clinical Evidence. [PDF]
J Immunol Res, 2022 Szukiewicz D +3 more
europepmc +1 more source