Results 21 to 30 of about 7,454,476 (197)

Characterization of Mast Cell Activation Syndrome. [PDF]

open access: yesAm J Med Sci, 2017
Afrin LB, Self S, Menk J, Lazarchick J.
europepmc   +2 more sources

Pathogenic Mechanisms of Vaccine-Induced Immune Thrombotic Thrombocytopenia in People Receiving Anti-COVID-19 Adenoviral-Based Vaccines: A Proposal

open access: yesFrontiers in Immunology, 2021
VITT is a rare, life-threatening syndrome characterized by thrombotic symptoms in combination with thrombocytopenia, which may occur in individuals receiving the first administration of adenoviral non replicating vectors (AVV) anti Covid19 vaccines ...
Bruno Azzarone   +3 more
doaj   +1 more source

A Puzzling Mast Cell Trilogy: Anaphylaxis, MCAS, and Mastocytosis

open access: yesDiagnostics, 2023
Our knowledge of biology and mast cell (MC) function, as well as disorders associated with the pathologic activation of MCs, has evolved over the last few decades.
Theo Gülen
doaj   +1 more source

Role of phosphoinositide 3-kinases in mast cell activation [PDF]

open access: yes, 2009
Mast cells are primary effector cells in allergy and chronic inflammation. Class IB (PI3Kγ) and class IA (PI3Kδ) PI3K have been shown to play major roles in mast cell activation: antigen/IgE stimulation triggers autocrine/paracrine activation of mast ...
Collmann, Emilie
core   +1 more source

Evaluation of Mast Cell Activation Syndromes: Impact of Pathology and Immunohistology [PDF]

open access: yes, 2012
Mast cell activation syndromes (MCAS) are clinically defined disease states with a largely unknown morphological background. Since mastocytosis may be associated with MCAS, it is crucial in every patient to document or exclude mastocytosis by appropriate
Horny, H. -P., Valent, P., Sotlar, K.
core   +1 more source

High FODMAP diet causes barrier loss via lipopolysaccharide-mediated mast cell activation

open access: yesJCI Insight, 2021
Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) are carbohydrates thought to contribute to the symptoms of IBS.
Prashant Singh   +5 more
doaj   +1 more source

Kounis Syndrome: Dexketoprofen-Associated ST-Elevation Myocardial Infarction

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2021
Allergic angina and allergic myocardial infarction are common diseases associated with acute coronary syndromes and encompass a wide spectrum of mast cell activation disorders termed "Kounis Syndrome".
Aytekin Aksakal   +3 more
doaj   +1 more source

Idiopathic Mast Cell Activation Syndrome With Associated Salicylate Intolerance [PDF]

open access: yes, 2020
Idiopathic mast cell activation syndrome can be a rare cause for chronic abdominal pain in children. It remains a diagnosis by exclusion that can be particularly challenging due to the vast variety of possible clinical manifestations.
Rechenauer, Tobias   +8 more
core   +1 more source

MiR-146a: a key microRNA involved in regulating mast cell survival and T lymphocyte differentiation [PDF]

open access: yes, 2013
Mast cells are long-lived, tissue-resident cells of the innate immune system. Since the identification of mechanisms that regulate mast cell proliferation, survival and overall homeostasis in the tissues may have important implications for the treatment ...
Rusca, Nicole-Lily
core   +1 more source

Case Report: Treatment of systemic mastocytosis with sunitinib [version 1; referees: 2 approved]

open access: yesF1000Research, 2017
Mast cell activation disease typically presents as chronic multisystem polymorbidity of generally inflammatory ± allergic theme.  Presently, treatment of the rare, cytoproliferative variant systemic mastocytosis employs empirically selected therapies to ...
Gerhard J. Molderings   +3 more
doaj   +1 more source

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