Results 11 to 20 of about 316,824 (311)
Mast cells in meningiomas [PDF]
Meningioma represents the most frequent tumor of the central nervous system (CNS). Correlations between the presence of mast cells (MCs) and grade or other histological features of meningioma are still debated. Our study aimed to better understand the relationship between mast cells and meningiomas and to compare our results based on specific ...
D'amati A.+4 more
openaire +5 more sources
Mast Cell Regulation of the Immune Response [PDF]
Mast cells are well known as principle effector cells of type I hypersensitivity responses. Beyond this role in allergic disease, these cells are now appreciated as playing an important role in many inflammatory conditions.
Johanna K. Morales+4 more
core +4 more sources
IgE Autoreactivity in Atopic Dermatitis: Paving the Road for Autoimmune Diseases?
Atopic dermatitis (AD) is a common skin disease affecting 20% of the population beginning usually before one year of age. It is associated with the emergence of allergen-specific IgE, but also with autoreactive IgE, whose function remain elusive.
Christophe Pellefigues
doaj +1 more source
Semaphorin-3 Promotes Specific Immunotherapy Effects on Experimental Food Allergy
Sustaining higher frequency of mast cells in the allergic lesion site has been recognized. Factors causing high numbers of mast cells in the local tissues are not fully understood yet.
Huang Huang+11 more
doaj +1 more source
Regulation of osteoclastogenesis by mast cell in rheumatoid arthritis
Background In the pathogenesis of rheumatoid arthritis (RA), the role of mast cells has not been revealed clearly. We aimed to define the inflammatory and tissue-destructive roles of mast cells in rheumatoid arthritis (RA).
Kyoung-Woon Kim+6 more
doaj +1 more source
Mast Cells: A New Frontier for Cancer Immunotherapy
Mast cells are unique tissue-resident immune cells of the myeloid lineage that have long been implicated in the pathogenesis of allergic and autoimmune disorders. More recently, mast cells have been recognized as key orchestrators of anti-tumor immunity,
Jake N. Lichterman, Sangeetha M. Reddy
doaj +1 more source
Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells
Mast cells are tissue-resident cells that contribute to allergic diseases, among others, due to excessive or inappropriate cellular activation and degranulation. Therapeutic approaches to modulate mast cell activation are urgently needed.
Piper A. Robida+15 more
doaj +1 more source
Mast cell-mediated immune regulation in health and disease
Mast cells are important components of the immune system, and they perform pro-inflammatory as well as anti-inflammatory roles in the complex process of immune regulation in health and disease.
Kottarappat N. Dileepan+8 more
doaj +1 more source
Special Glass Structures for First Principles Studies of Bulk Metallic Glasses [PDF]
The atomic-level structure of bulk metallic glasses is a key determinant of their properties. An accurate representation of amorphous systems in computational studies has traditionally required large supercells that are unfortunately computationally demanding to handle using the most accurate ab initio calculations.
arxiv +1 more source
Degranulated mast cells and TNF-α in oral lichen planus and oral lichenoid reactions diseases
Background: The objective of this study was to assess mast cells and TNF-α in oral lichen planus (OLP) and oral lichenoid reactions (OLR) patients as diagnostic marker to the differential diagnosis of OLP and OLR diseases.
Parichehr Ghalayani+2 more
doaj +1 more source