Results 21 to 30 of about 143,658 (169)
Toxins, 2016 The association of colitis with colorectal cancer has become increasingly clear with mast cells being identified as important inflammatory cells in the process.
Shan Wang +7 more
doaj +1 more source
Isolation and Culture of Bone Marrow-derived Mast Cells
Bio-Protocol, 2014 The generation of mast cells for in vitro studies comes from a variety of sources including mast cell lines (MC/9) (McCurdy et al., 2001), bone marrow-derived mast cells (BMMCs) (Supajatura et al., 2001), skin-derived mast cells (FSMCs) (Matsushima et al.
Krisztina Vukman +3 more
doaj +1 more source
Journal for ImmunoTherapy of Cancer, 2019 Background Mast cells are prominent components of solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, the nature, regulation, function, and clinical relevance of mast cells in human gastric cancer (GC) are ...
Yipin Lv +18 more
doaj +1 more source
The mast cell and mast cell disease
Journal of the American Academy of Dermatology, 1995 Mast cell disease or mastocytosis is a heterogeneous group of clinical disorders characterized by the proliferation and accumulation of mast cells in a variety of tissues, most often the skin. The signs and symptoms of mast cell disease are varied, dependent on the localization of mast cells in different organs and the local and systemic effects of ...
J, Longley, T P, Duffy, S, Kohn
openaire +2 more sources
Mast Cell Activation Disorders [PDF]
Medicina, 2021 Background and Objectives: Mast cell disorders comprise a wide spectrum of syndromes caused by mast cells’ degranulation with acute or chronic clinical manifestations. Materials and Methods: In this review article we reviewed the latest findings in scientific papers about mast cell disorders with a particular focus on mast cell activation syndrome and ...
Arianna Giannetti +4 more
openaire +5 more sources
Relationship between numerous mast cells and early follicular development in neonatal MRL/MpJ mouse ovaries. [PDF]
PLoS ONE, 2013 In the neonatal mouse ovary, clusters of oocytes called nests break into smaller cysts and subsequently form individual follicles. During this period, we found numerous mast cells in the ovary of MRL/MpJ mice and investigated their appearance and ...
Teppei Nakamura +6 more
doaj +1 more source
Mast Cells and Skin and Breast Cancers: A Complicated and Microenvironment-Dependent Role
Cells, 2021 Mast cells are important sentinel cells in host defense against infection and major effector cells in allergic disease. The role of these cells in cancer settings has been widely debated.
Mark R. Hanes +2 more
doaj +1 more source
BMC Immunology, 2010 Background Mast cells have recently gained new importance as immunoregulatory cells that are involved in numerous pathological processes. One result of these processes is an increase in mast cell numbers at peripheral sites.
Pastor Maria +8 more
doaj +1 more source
Frontiers in Oncology, 2021 Tumor cells require signaling and close interaction with their microenvironment for their survival and proliferation. In the recent years, Mast cells have earned a greater importance for their presence and role in cancers. It is known that mast cells are
Deeksha Mehtani, Niti Puri
doaj +1 more source
Journal of Histochemistry & Cytochemistry, 2012 Mast cells are versatile effector cells of the immune system, contributing to both innate and adaptive immunity toward pathogens but also having profound detrimental activities in the context of inflammatory disease. A hallmark morphological feature of mast cells is their large content of cytoplasmic secretory granules, filled with numerous secretory ...
Elin, Rönnberg +2 more
openaire +2 more sources